Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Yongzhong Du"'
Autor:
Yichao Lu, Zhenyu Luo, Huanli Zhou, Yingying Shi, Ying Zhu, Xuemeng Guo, Jiaxin Huang, Junlei Zhang, Xu Liu, Sijie Wang, Xinyu Shan, Hang Yin, Yongzhong Du, Qingpo Li, Jian You, Lihua Luo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Obesity often leads to severe medical complications. However, existing FDA-approved medications to combat obesity have limited effectiveness in reducing adiposity and often cause side effects. These medications primarily act on the central n
Externí odkaz:
https://doaj.org/article/138fbac84ea047248f3c37f7dc94de99
Autor:
Di Liu, Yanling Song, Hui Chen, Yuchan You, Luwen Zhu, Jucong Zhang, Xinyi Xu, Jiahao Hu, Xiajie Huang, Xiaochuan Wu, Xiaoling Xu, Saiping Jiang, Yongzhong Du
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Poor renal distribution of antibody-based drugs is the key factor contributing to low treatment efficiency for renal diseases and side effects. Here, we prepare F(ab′)2 fragmented vascular endothelial growth factor receptor 2 antibody (ant
Externí odkaz:
https://doaj.org/article/0be0f897c36d40419a5c775825212f5e
Autor:
Jun Wang, Wei Wang, Qingmei Shen, Lan Lan, Cuiping Guan, Xinchang Xu, Weishuo Li, Yongzhong Du
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Calcium (Ca2+) is essential for mitochondrial homeostasis and function coordination, particularly in cancer cells that metabolize frequently to sustain their growth. Photochemistry mediated calcium overload has attracted lots of attention as
Externí odkaz:
https://doaj.org/article/b15be34ba81644f09a613262fd6d257b
Autor:
Yanling Song, Yuchan You, Xinyi Xu, Jingyi Lu, Xiajie Huang, Jucong Zhang, Luwen Zhu, Jiahao Hu, Xiaochuan Wu, Xiaoling Xu, Weiqiang Tan, Yongzhong Du
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds. Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy healing times, risk of immune rejection, and susceptibility t
Externí odkaz:
https://doaj.org/article/f35634eee9864e5c89907dfcf5c74edc
Autor:
Gaofeng Shu, Lin Shen, Jiayi Ding, Junchao Yu, Xiaoxiao Chen, Xiaoju Guo, Enqi Qiao, Yaning Chen, Chenying Lu, Zhongwei Zhao, Yongzhong Du, Minjiang Chen, Jiansong Ji
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 6, Pp 908-923 (2022)
The development of novel theranostic agents with outstanding diagnostic and therapeutic performances is still strongly desired in the treatment of hepatocellular carcinoma (HCC). Here, a fucoidan-modified mesoporous polydopamine nanoparticle dual-loa
Externí odkaz:
https://doaj.org/article/eb714cba943c465fb0493ac43313fea1
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 5, Pp 100846- (2023)
Psoriasis is an inflammatory skin disease that is intricately linked to oxidative stress. Antioxidation and inhibition of abnormal proliferation of keratinocytes are pivotal strategies for psoriasis. Delivering drugs with these effects to the site of
Externí odkaz:
https://doaj.org/article/26b05e5e49554517a9c3ec02a556a0a6
Autor:
Xiaojuan Wang, Xiaoling Xu, Shaojun Zhang, Na Chen, Yunfeng Sun, Kuifen Ma, Dongsheng Hong, Lu Li, Yongzhong Du, Xiaoyang Lu, Saiping Jiang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Overproduction of efflux pumps represents an important mechanism of Klebsiella pneumonia resistance to tigecycline. Here, the authors design TPGS- and S-thanatin functionalized nanorods loaded with tigecycline to increase drug accumulation inside bac
Externí odkaz:
https://doaj.org/article/06e642d04b1a4ebab01fe1b00e216b51
Autor:
Zhenyu Luo, Lihua Luo, Yichao Lu, Chunqi Zhu, Bing Qin, Mengshi Jiang, Xiang Li, Yingying Shi, Junlei Zhang, Yu Liu, Xinyu Shan, Hang Yin, Guannan Guan, Yongzhong Du, Ningtao Cheng, Jian You
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Adoptive cell therapy (ACT) was one of the most promising anti-tumor modalities that has been confirmed to be especially effective in treating hematological malignancies. However, the clinical efficacy of ACT on solid tumor was greatly hinde
Externí odkaz:
https://doaj.org/article/3cfc3ccc0be543669b7268a07f33987d
Autor:
Minjiang Chen, Jie Li, Gaofeng Shu, Lin Shen, Enqi Qiao, Nannan Zhang, Shiji Fang, Xiaoxiao Chen, Zhongwei Zhao, Jianfei Tu, Jingjing Song, Yongzhong Du, Jiansong Ji
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Transcatheter arterial chemoembolization (TACE) is one of the main palliative therapies for advanced hepatocellular carcinoma (HCC), which is also regarded as a promising therapeutic strategy for cancer treatment. However, drug-loaded micros
Externí odkaz:
https://doaj.org/article/0e24203b96bb4e2d8eb6b4032f031dfe
Autor:
Bing Qin, Mengshi Jiang, Xiang Li, Yingying Shi, Junlei Zhang, Zhenyu Luo, Lihua Luo, Yichao Lu, Xu Liu, Sijie Wang, Yongzhong Du, Yunqing Qiu, Yan Lou, Jian You
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Gene therapy shows great promise for a broad array of diseases. However, we found that hypoxic tumor microenvironment (TME) exerted significant inhibitory effects on transfection efficiency of a variety of gene vectors (such as Li
Externí odkaz:
https://doaj.org/article/4d5f9e8be10344e7b8edc597e3ef9d06