Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Yongzhen Xia"'
Publikováno v:
mLife, Vol 3, Iss 2, Pp 231-239 (2024)
Abstract Members of the multiple antibiotic resistance regulator (MarR) protein family are ubiquitous in bacteria and play critical roles in regulating cellular metabolism and antibiotic resistance. MarR family proteins function as repressors, and th
Externí odkaz:
https://doaj.org/article/daadbcc55ca345f49bfad6c3c61695c0
Autor:
Xiaohui Chen, Meichun Gao, Yongzhen Xia, Xin Wang, Jingbo Qin, Hongying He, Weirong Liu, Xiaowei Zhang, Shuangzhou Peng, Zhiping Zeng, Ying Su, Xiaokun Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1204-1221 (2024)
The orphan nuclear receptor Nur77 is a critical regulator of the survival and death of tumor cells. The pro-death effect of Nur77 can be regulated by its interaction with Bcl-2, resulting in conversion of Bcl-2 from a survival to killer. As Bcl-2 is
Externí odkaz:
https://doaj.org/article/9099f275d897481e906a2e2142a26210
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Methanethiol (MT) is a sulfur-containing compound produced during dimethylsulfoniopropionate (DMSP) degradation by marine bacteria. The C–S bond of MT can be cleaved by methanethiol oxidases (MTOs) to release a sulfur atom. However, the cl
Externí odkaz:
https://doaj.org/article/322083a14d4145fd943d0be2e88f3bff
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 589 (2024)
YCA1, the only metacaspase in Saccharomyces cerevisiae, plays important roles in the regulation of chronological lifespan, apoptosis, and cytokinesis. YCA1 has protein hydrolase activity and functions by cleaving itself and target proteins. However,
Externí odkaz:
https://doaj.org/article/c29c479f4f334947823aac11f3dbe50a
Autor:
Chao Tang, Jingjing Li, Yuemeng Shen, Menghui Liu, Honglei Liu, Huaiwei Liu, Luying Xun, Yongzhen Xia
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
The feather-degrading bacterium Bacillus licheniformis MW3 contains a sulfur-metabolizing gene cluster, in which one sulfide-sensor and one sulfane sulfur-sensor synergistically control gene expression, enabling the bacterium to grow on bird feathers
Externí odkaz:
https://doaj.org/article/51a889f495fb4f0da4ea360a7c7cafa4
Autor:
Honglei Liu, Huiyuan Yu, Rui Gao, Fulin Ge, Rui Zhao, Xia Lu, Tianqi Wang, Huaiwei Liu, Chunyu Yang, Yongzhen Xia, Luying Xun
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 27 (2023)
Podophyllotoxin (PTOX) is naturally produced by the plant Podophyllum species. Some of its derivatives are anticancer drugs, which are produced mainly by using chemical semi-synthesis methods. Recombinant bacteria have great potential in large-scale
Externí odkaz:
https://doaj.org/article/0023de5e67b241ae8c90f16301054ee3
An Optimized Transformation Protocol for Escherichia coli BW3KD with Supreme DNA Assembly Efficiency
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT DNA cloning requires two steps: the assembly of recombinant DNA molecules and the transformation of the product into a host organism for replication. High efficiencies in both processes can increase the success rate. Recently, we developed a
Externí odkaz:
https://doaj.org/article/848b5127b9144d4597e67f1ddccbc732
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Hyperuricemia is the second most prevalent metabolic disease to human health after diabetes. Only a few clinical drugs are available, and most of them have serious side effects. The human body does not have urate oxidase, and uric acid is secreted vi
Externí odkaz:
https://doaj.org/article/4f266c6865904f3ba1757c69e293748e
Autor:
Daixi Liu, Jinyu Chen, Yafei Wang, Yue Meng, Yuanning Li, Ranran Huang, Yongzhen Xia, Huaiwei Liu, Nianzhi Jiao, Luying Xun, Jihua Liu
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Cyanobacteria are a widely distributed group of microorganisms in the ocean, and they often need to cope with the stress of reactive sulfur species, such as sulfide and sulfane sulfur. Sulfane sulfur refers to the various forms of zero-valen
Externí odkaz:
https://doaj.org/article/47e7149944a446cdab70adcdac5afc87
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1127 (2023)
Hydrogen sulfide (H2S) and its oxidation product zero-valent sulfur (S0) play important roles in animals, plants, and bacteria. Inside cells, S0 exists in various forms, including polysulfide and persulfide, which are collectively referred to as sulf
Externí odkaz:
https://doaj.org/article/0da8481de0b14a3d9478d761fab0d6c0