Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Yongyi Ye"'
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1178-1191 (2025)
Microglia, the primary immune cells within the brain, have gained recognition as a promising therapeutic target for managing neurodegenerative diseases within the central nervous system, including Parkinson’s disease. Nanoscale perfluorocarbon drop
Externí odkaz:
https://doaj.org/article/01e121aa553b421db14ca087e187a17f
Autor:
Zhixin Xie, Haobin Zhou, Ziyu Qiu, Zhongxi Fan, Weisheng Yang, Jingbai Zhang, Yezhong Wang, Yongyi Ye
Publikováno v:
Brain and Behavior, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Parkinson's disease (PD) is a common degenerative nervous system disease. At present, there are certain limitations in various treatment options aimed at preventing or delaying the progression of PD. Therefore, the exploration of
Externí odkaz:
https://doaj.org/article/655b1e42c2094423a1ba006f787aeacb
Autor:
Haiyan Wang, Hanqing Lin, Weibiao Kang, Lingfei Huang, Sisi Gong, Tao Zhang, Xiaotong Huang, Feinan He, Yongyi Ye, Yiyang Tang, Haiying Jia, Haidi Yang
Publikováno v:
BMC Pharmacology and Toxicology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Purpose Cisplatin is a widely used and effective chemotherapeutic agent for most solid malignant tumors. However, cisplatin-induced ototoxicity is a common adverse effect that limits the therapeutic efficacy of tumors in the clinic. To date,
Externí odkaz:
https://doaj.org/article/13b353a252794624843c24b52e02def3
Autor:
Chuanfang Wang, Yunxiang Ji, Huabin Zhang, Yongyi Ye, Guilong Zhang, Shizhen Zhang, Chengcheng Zhao, Yezhong Wang
Publikováno v:
Neurobiology of Disease, Vol 179, Iss , Pp 106042- (2023)
Mild hypothermia has been proven to inhibit microglia activation after TBI. Exosomal microRNA derived from microglia played a critical role in promoting neurite outgrowth and synapse recovery. Here, we aimed to investigate the role of microRNAs in mi
Externí odkaz:
https://doaj.org/article/da736a95f80d43e7967682c82edf9fc0
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The intracellular aggregation of α-synuclein in neurons/glia is considered to be a key step in the pathogenesis of synucleinopathy [including Parkinson’s disease (PD), dementia with Lewy body (DLB), multiple system atrophy (MSA), etc.]. Increasing
Externí odkaz:
https://doaj.org/article/65f75dbb11d34aa88f75a6b60461805d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Autophagy dysfunction has been directly linked with the onset and progression of Parkinson’s disease (PD), but the underlying mechanisms are not well understood. High-mobility group A1 (HMGA1), well-known chromatin remodeling proteins, play pivotal
Externí odkaz:
https://doaj.org/article/0053f4ac923141bca0a10496451c20a5
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background Parkinson’s disease (PD) is the most prevalent neurodegenerative disorder that is characterised by selective loss of midbrain dopaminergic (DA) neurons. Chronic inflammation of the central nervous system is mediated by microglia
Externí odkaz:
https://doaj.org/article/7070343d1d1d415582a9d12918838e55
Autor:
Jiaqi Pang, Hao Xiong, Ting Zhan, Gui Cheng, Haiying Jia, Yongyi Ye, Zhongwu Su, Hongyu Chen, Hanqing Lin, Lan Lai, Yongkang Ou, Yaodong Xu, Suijun Chen, Qiuhong Huang, Maojin Liang, Yuexin Cai, Xueyuan Zhang, Xiaoding Xu, Yiqing Zheng, Haidi Yang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2019)
Cisplatin-induced ototoxicity is one of the major adverse effects in cisplatin chemotherapy, and hearing protective approaches are unavailable in clinical practice. Recent work unveiled a critical role of autophagy in cell survival in various types o
Externí odkaz:
https://doaj.org/article/a7cf60cb795d43c7936ab5c6f120acf9
Autor:
Yiqing Zheng, Yongyi Ye, Haidi Yang, Ting Zhan, Wuhui He, Xin Min, Xiaotong Huang, Jiaqi Pang, Hao Xiong, Weijian Zhang, Feinan He, Zhengrong Liang, Bingquan Jian, Yiming Gao
Publikováno v:
Toxicology Letters. 349:115-123
Cisplatin, the most widely used platinum-based anticancer drug, often causes progressive and irreversible sensorineural hearing loss in cancer patients. However, the precise mechanism underlying cisplatin-associated ototoxicity is still unclear. Nico
Publikováno v:
Journal of Architectural Environment & Structural Engineering Research. 4:20-30
It is important to improve residential thermal comfort in the high dense cities, in which wind environment is crucial. Waterside buildings take an advantage of micro-hydrological-climate in summer that should be used to enhance residential thermal co