Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Yongxu Jia"'
Autor:
Zhiwei Chang, Yongxu Jia, Ming Gao, Lijie Song, Weijie Zhang, Ruihua Zhao, Dandan Yu, Xiaolei Liu, Jing Li, Yanru Qin
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is the main subtype of esophageal cancer. Current therapeutic effect is far from satisfaction. Hence, identifying susceptible genes and potential targets is necessary for therapy of ESCC p
Externí odkaz:
https://doaj.org/article/90c3d28fbc274f6299ab7a25a3513059
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Gastric cancer (GC) ranks fifth for morbidity and third for mortality worldwide. The N6-methyladenosine (m6A) mRNA methylation is crucial in cancer biology and progression. However, the relationship between m6A methylation and gas
Externí odkaz:
https://doaj.org/article/c8fa980901ff454ca122d9b89790d94f
Autor:
Yongxu Jia, Qian Yan, Yinli Zheng, Lei Li, Baifeng Zhang, Zhiwei Chang, Zehua Wang, Hong Tang, Yanru Qin, Xin-Yuan Guan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Background Lymph node metastasis is one of most common determinants of the stage and prognosis of gastric cancer (GC). However, the key molecular events and mechanisms mediating lymph node metastasis remain elusive. Methods RNA sequencing wa
Externí odkaz:
https://doaj.org/article/34d34eaab4fc4d33aae6358aa75fc38a
Autor:
Yongxu Jia, Baifeng Zhang, Chunyang Zhang, Dora Lai‐Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xinyuan Guan, Yanru Qin
Publikováno v:
Advanced Science, Vol 10, Iss 7, Pp n/a-n/a (2023)
Abstract Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma (ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the transcriptomes of 85 263 single cells are analyzed from four ESCC pa
Externí odkaz:
https://doaj.org/article/3ead2ae655c34a8ca5dbff1b542f5065
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple myeloma (MM) is a malignant plasma cell disorder that remains incurable for most patients, as persistent clonal evolution drives new mutations which confer MM high-risk signatures and resistance to standard care. The past two decades have si
Externí odkaz:
https://doaj.org/article/4d82c555e8194453844e167bbea3b319
Autor:
Zhiwei Chang, Yang Fu, Yongxu Jia, Ming Gao, Lijie Song, Weijie Zhang, Ruihua Zhao, Yanru Qin
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Increasing studies focused on the regulatory roles of circular RNAs (circRNAs) in diverse cancers. This study was to evaluate the function and mechanism of circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) i
Externí odkaz:
https://doaj.org/article/9dd12217b48848f28d80c839fb15b32a
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Megakaryocytic leukemia 1 (MKL1) is a key transcription factor involved in non-small cell lung cancer (NSCLC) growth and metastasis. Yet, its downstream target genes, especially long non-coding RNA (lncRNA) targets, are poorly investigated.
Externí odkaz:
https://doaj.org/article/fbaf541e4567488c98a9f49fac838f4d
Publikováno v:
Translational Oncology, Vol 11, Iss 2, Pp 205-212 (2018)
Glioma is the most common cancer in human brain system and seriously threatens human health. miRNA-320 has been demonstrated to be closely correlated with the development of glioma. However, its effect and molecular mechanism underlying radioresistan
Externí odkaz:
https://doaj.org/article/fc99056908364c5191b1d57accf2a69d
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88918 (2014)
AIM:Esophageal squamous cell carcinoma (ESCC) is one of the most common fatal malignances of the digestive tract. Its prognosis is poor mainly due to the lack of reliable markers for early detection and prognostic prediction. Here we aim to identify
Externí odkaz:
https://doaj.org/article/8756e330988641b391801de906327d18
Autor:
Ka-On Lam, Xin-Yuan Guan, Xiang Lin, Yanru Qin, Yan Li, Krista R. Verhoeft, Ying Tang, Ying Wang, Liang-Zhan Sun, Yu-Zhu Cui, Yongxu Jia, Zhaojie Lv, Feifei Zhang, Jiao Huang, Miao Chen, Shayi Wu
The ubiquitous second messenger Ca2+ has long been recognized as a key regulator in cell migration. Locally confined Ca2+, in particular, is essential for building front-to-rear Ca2+ gradient, which serves to maintain the morphologic polarity require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3250d8b5df552550d26a9a1c629a984
https://doi.org/10.1158/0008-5472.c.6512439
https://doi.org/10.1158/0008-5472.c.6512439