Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Yongxin, Jin"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Antibiotic drug combination therapy is critical for the successful treatment of infections caused by multidrug resistant pathogens. We investigated the efficacy of β-lactam and β-lactam/β-lactamase inhibitor combinations with other antibiotics, ag
Externí odkaz:
https://doaj.org/article/889eb318d7c54984b634a5626c15eed3
Autor:
Xiaoya Wei, Dandan Zhou, Congjuan Xu, Ping Chen, Shuiping Chen, Zhihui Cheng, Yongxin Jin, Shouguang Jin, Weihui Wu
Publikováno v:
Antibiotics, Vol 13, Iss 9, p 810 (2024)
Pseudomonas aeruginosa is a multidrug-resistant Gram-negative pathogen and one of the leading causes of ventilator-associated pneumonia and infections in patients with chronic obstructive pulmonary disease and cystic fibrosis. Murepavadin is a peptid
Externí odkaz:
https://doaj.org/article/7c85eba8fd034aea8f26529847b610e7
Autor:
Liwen Yin, Qi Liu, Xiaolei Pan, Chenjing Lv, Yuxi Bai, Fang Bai, Zhihui Cheng, Weihui Wu, Un-Hwan Ha, Yongxin Jin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Pseudomonas aeruginosa is an opportunistic human pathogen capable of causing a variety of acute and chronic infections. Its type III secretion system (T3SS) plays a critical role in pathogenesis during acute infection. ExsA is a master regulator that
Externí odkaz:
https://doaj.org/article/3584c2b269e840a7862aa394eefcf30f
Autor:
Xiaoya Wei, Jiacong Gao, Congjuan Xu, Xiaolei Pan, Yongxin Jin, Fang Bai, Zhihui Cheng, Iain L. Lamont, Daniel Pletzer, Weihui Wu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can cause a variety of acute and chronic infections. The bacterium is highly resistant to numerous antibiotics. Murepavadin is a peptidomimetic antibiotic that blocks the fun
Externí odkaz:
https://doaj.org/article/31c948b662b64e539d820237b2847c64
Publikováno v:
Engineering Applications of Computational Fluid Mechanics, Vol 16, Iss 1, Pp 501-513 (2022)
Investigating the flow characteristics in the cavity by changing the rotor profile of the rotor-stator system is of considerable significance, this paper simplifies clearance flow to rotor-stator cavity flow. The numerical simulation results are comp
Externí odkaz:
https://doaj.org/article/639c7374ffd640a787b035f6fe9288aa
Autor:
Fan Yang, Yuchen Zhou, Yuxi Bai, Xiaolei Pan, Un-Hwan Ha, Zhihui Cheng, Weihui Wu, Yongxin Jin, Fang Bai
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Polymyxins are currently the last-resort antibiotics for the treatment of multidrug-resistant Gram-negative bacterial infections. To expand the understanding of the intrinsic resistance mechanism against polymyxins, a laboratory strain of Ps
Externí odkaz:
https://doaj.org/article/bfc25eadd7f34cc19ba2efca9edba31f
Autor:
Yuchen Zhou, Jing Qu, Xiaomeng Sun, Zhuo Yue, Yingzi Liu, Keli Zhao, Fan Yang, Jie Feng, Xiaolei Pan, Yongxin Jin, Zhihui Cheng, Liang Yang, Un-Hwan Ha, Weihui Wu, Liang Li, Fang Bai
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
COVID-19 pandemic continues to spread throughout the world with an urgent demand for a safe and protective vaccine to effectuate herd protection and control the spread of SARS-CoV-2. Here, we report the development of a bacterial vector COVID-19 vacc
Externí odkaz:
https://doaj.org/article/b503161cf7174c2a8e4046f3b9a0d7cb
Autor:
Hao Chen, Xuetao Gong, Zheng Fan, Yushan Xia, Yongxin Jin, Fang Bai, Zhihui Cheng, Xiaolei Pan, Weihui Wu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Carbohydrate metabolism plays essential roles in energy generation and providing carbon skeletons for amino acid syntheses. In addition, carbohydrate metabolism has been shown to influence bacterial susceptibility to antibiotics and virulenc
Externí odkaz:
https://doaj.org/article/fa48060666954f9fb35c0c329a4b29aa
Autor:
Qi’an Liang, Jiaqi Yan, Shuwen Zhang, Nan Yang, Meifang Li, Yongxin Jin, Fang Bai, Weihui Wu, Zhihui Cheng
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), is a Gram-negative obligatory intracellular bacterium, which infects and multiplies in human monocytes and macrophages. Host immune cells produce reactive oxygen specie
Externí odkaz:
https://doaj.org/article/13f90630af59424a83c9f3017d64d225
Autor:
Congjuan Xu, Xiaoya Wei, Yongxin Jin, Fang Bai, Zhihui Cheng, Shuiping Chen, Xiaolei Pan, Weihui Wu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT The evolution of bacterial antibiotic resistance is exhausting the list of currently used antibiotics and endangers those in the pipeline. The combination of antibiotics is a promising strategy that may suppress resistance development and/or
Externí odkaz:
https://doaj.org/article/4aa94fdab7164193a973a0b829bd48d1