Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yongxia Huo"'
Autor:
Shiwu Li, Changguo Ma, Yifan Li, Rui Chen, Yixing Liu, Li Pear Wan, Qiuxia Xiong, Chuang Wang, Yongxia Huo, Xinglun Dang, Yongfeng Yang, Luxian Lv, Xi Chen, Nengyin Sheng, Wenqiang Li, Xiong-Jian Luo
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The missense variant rs13107325 (C/T, p.Ala391Thr) in SLC39A8 consistently showed robust association with schizophrenia in recent genome-wide association studies (GWASs), suggesting the potential pathogenicity of this non-synonymous risk var
Externí odkaz:
https://doaj.org/article/b00f5596114d497d98229245a2eff30e
Autor:
Rui Chen, Zhihui Yang, Jiewei Liu, Xin Cai, Yongxia Huo, Zhijun Zhang, Ming Li, Hong Chang, Xiong-Jian Luo
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Genome-wide association studies (GWASs) have identified multiple risk loci for bipolar disorder (BD). However, pinpointing functional (or causal) variants in the reported risk loci and elucidating their regulatory mechanisms remai
Externí odkaz:
https://doaj.org/article/6fcb5061bf8d4339b3c40423d845fca3
Autor:
Rui Chen, Jiewei Liu, Shiwu Li, Xiaoyan Li, Yongxia Huo, Yong-Gang Yao, Xiao Xiao, Ming Li, Xiong-Jian Luo
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Genome-wide association studies (GWASs) have identified multiple risk loci for Parkinson’s disease (PD). However, identifying the functional (or potential causal) variants in the reported risk loci and elucidating their roles in
Externí odkaz:
https://doaj.org/article/903a6fb3fbbe4cf59705ec86a9b109a1
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
We know a large number of risk SNPs for schizophrenia, but little about how these SNPs contribute to the disorder. Here, the authors use functional genomics to identify risk SNPs that disrupt transcription factor binding and validate the regulatory e
Externí odkaz:
https://doaj.org/article/84007106e80b429e9d5b74bc356226ca
Autor:
Cui-Ping Yang, Xiaoyan Li, Yong Wu, Qiushuo Shen, Yong Zeng, Qiuxia Xiong, Mengping Wei, Chunhui Chen, Jiewei Liu, Yongxia Huo, Kaiqin Li, Gui Xue, Yong-Gang Yao, Chen Zhang, Ming Li, Yongbin Chen, Xiong-Jian Luo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
More than 100 risk loci for schizophrenia have been identified by genome-wide association studies. Here, the authors apply an integrative genomic approach to prioritize risk genes and validate GLT8D1 and CSNK2B as candidate causal genes by in vitro s
Externí odkaz:
https://doaj.org/article/ba12e6b9e8a940f9954895f9f71b1408
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background The Zika virus (ZIKV) is a mosquito-borne flavivirus that causes microcephaly and Guillain-Barré syndrome in infected individuals. To obtain insights into the mechanism of ZIKV infection and pathogenesis, we analyzed the transcri
Externí odkaz:
https://doaj.org/article/2167d12262e241bb9a28fb0006eab5de
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-1 (2019)
In the original publication of this article [1], two grants from National Science Foundation of China and Yunnan Provincial Government (U1602226) and by National Science Foundation of China (2016YFC1200404) were omitted in the ‘Funding’ section.
Externí odkaz:
https://doaj.org/article/1f9ff4cff6d249a387578654a1526996
Autor:
Cui-Ping Yang, Xiaoyan Li, Yong Wu, Qiushuo Shen, Yong Zeng, Qiuxia Xiong, Mengping Wei, Chunhui Chen, Jiewei Liu, Yongxia Huo, Kaiqin Li, Gui Xue, Yong-Gang Yao, Chen Zhang, Ming Li, Yongbin Chen, Xiong-Jian Luo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, the affiliation details for Qiushuo Shen incorrectly omitted ‘Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, 650204, China’. This has now been corrected in both the PD
Externí odkaz:
https://doaj.org/article/380c3535e334446fb4dc71740f44c73d
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 186:28-39
Schizophrenia is a severe mental disease characterized with positive symptoms, negative symptoms, and cognitive impairments. Although recent genome-wide association studies (GWASs) have identified over 145 risk loci for schizophrenia, pinpointing the
Publikováno v:
Molecular Psychiatry. 26:7102-7104