Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Yongwei, Zheng"'
Autor:
Gang Hu, Guangchao Li, Wei Wen, Wen Ding, Zhao Zhou, Yongwei Zheng, Taoyuan Huang, Junnan Ren, Rongyi Chen, Dingheng Zhu, Renliang He, Yunsheng Liang, Min Luo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
B7-H3 is over-expressed in multiple types of solid tumors, making it an ideal target for chimeric antigen receptor (CAR)-T therapy. Here, we first report a case of multiple basal cell carcinoma (BCC) patient treated with humanized monoclonal anti-B7-
Externí odkaz:
https://doaj.org/article/2f81d9adc30d4d80ac305f6ccbc1e5d7
Autor:
Yuhong Chen, Mei Yu, Yongwei Zheng, Guoping Fu, Gang Xin, Wen Zhu, Lan Luo, Robert Burns, Quan-Zhen Li, Alexander L. Dent, Nan Zhu, Weiguo Cui, Laurent Malherbe, Renren Wen, Demin Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
B cell response and antibody production are generally facilitated by CD4+ follicular helper (Tfh) cells. Here the authors identify a subset of CXCR5+PD1+CD8+ Tfh cells that is normally suppressed by STAT5 signaling, so that STAT5 deficiency in mice i
Externí odkaz:
https://doaj.org/article/3b58b83ee76b4ab8925812d290639692
Autor:
Yongwei Zheng, Mei Yu, Yuhong Chen, Liquan Xue, Wen Zhu, Guoping Fu, Stephan W. Morris, Renren Wen, Demin Wang
Publikováno v:
The Journal of Immunology. 210:1222-1235
The caspase recruitment domain family member (CARD)11-Bcl10-Malt1 signalosome controls TGF-β–activated kinase 1 (TAK1) activation and regulates BCR-induced NF-κB activation. In this study, we discovered that CARD19 interacted with TAK1 and inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33cb1599d76e0a6aeb3b787259e2fd92
https://doi.org/10.4049/jimmunol.2200639
https://doi.org/10.4049/jimmunol.2200639
Autor:
Jie Li, Liansheng Zhang, Yongwei Zheng, Rui Shao, Qianqian Liang, Weida Yu, Hongyan Wang, Weiguo Zou, Demin Wang, Jialing Xiang, Anning Lin
Publikováno v:
eLife, Vol 9 (2020)
The resistance of synovial sublining macrophages to apoptosis has a crucial role in joint inflammation and destruction in rheumatoid arthritis (RA). However, the underlying mechanism is incompletely understood. Here we report that inactivation of the
Externí odkaz:
https://doaj.org/article/ac5bc1a261134b02ad49f78bdc3d64de
Publikováno v:
Giant, Vol 2, Iss , Pp 100021- (2020)
Solid polymer electrolytes (SPEs) are promising for the next-generation all-solid-state lithium metal battery (LMB) applications. The effect of semicrystalline structure on ion transport is two-fold: the crystalline domains provide a tortuous diffusi
Externí odkaz:
https://doaj.org/article/1501b72dfb27461a8467c1f44d5add6f
Autor:
Chao Yang, Jason R Siebert, Robert Burns, Yongwei Zheng, Ao Mei, Benedetta Bonacci, Demin Wang, Raul A Urrutia, Matthew J Riese, Sridhar Rao, Karen-Sue Carlson, Monica S Thakar, Subramaniam Malarkannan
Publikováno v:
eLife, Vol 9 (2020)
The transcriptional activation and repression during NK cell ontology are poorly understood. Here, using single-cell RNA-sequencing, we reveal a novel role for T-bet in suppressing the immature gene signature during murine NK cell development. Based
Externí odkaz:
https://doaj.org/article/9738a645226d43e4b9f73828d7f1156b
Autor:
Hui Zhang, Chaoke Bu, Zhiyong Peng, Guangchao Li, Zhao Zhou, Wen Ding, Yongwei Zheng, Yingyi He, Zhengbin Hu, Kunlin Pei, Min Luo, Chunfu Li
Publikováno v:
Leukemia. 36:2596-2604
C-type lectin like molecule-1 (CLL1) is preferentially expressed on acute myeloid leukemia (AML) stem cells and AML blasts, and can be considered as AML-associated antigen. Anti-CLL1-based CAR-T cells exhibited effective tumor killing capacity in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09c55a8eeb5bd3ec1f95f93c471e5c
https://doi.org/10.1038/s41375-022-01703-0
https://doi.org/10.1038/s41375-022-01703-0
Autor:
Mei Yu, Yuhong Chen, Hu Zeng, Yongwei Zheng, Guoping Fu, Wen Zhu, Ulrich Broeckel, Praful Aggarwal, Amy Turner, Geoffrey Neale, Cliff Guy, Nan Zhu, Hongbo Chi, Renren Wen, Demin Wang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
IL-7R activation drives early B cell development, but the signalling is unclear. Here the authors show PLCγ is involved in IL-7R-induced mTOR activation via a DAG/PKC-dependent pathway, and that double deficiency of the two PLCγ isoforms arrests B
Externí odkaz:
https://doaj.org/article/c452dfc952154a9d82178c4541f18fa3
Autor:
Li Wang, Subramaniam Malarkannan, Demin Wang, Marc S. Ernstoff, Kamalakannan Rajasekaran, Michael Olson, Halli E. Miller, Hieu Minh Ta, Ying Yuan, Juan Zhou, Yongwei Zheng, Juan Dong, Wenwen Xu
Immune-checkpoint protein V-domain immunoglobulin suppressor of T-cell activation (VISTA) controls antitumor immunity and is a valuable target for cancer immunotherapy. This study identified a role of VISTA in regulating Toll-like receptor (TLR) sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb7905f2c8e939c86b7a01e640b825e
https://doi.org/10.1158/2326-6066.c.6550056
https://doi.org/10.1158/2326-6066.c.6550056
Autor:
Li Wang, Subramaniam Malarkannan, Demin Wang, Marc S. Ernstoff, Kamalakannan Rajasekaran, Michael Olson, Halli E. Miller, Hieu Minh Ta, Ying Yuan, Juan Zhou, Yongwei Zheng, Juan Dong, Wenwen Xu
Figure S1 S2 and S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190fc45911e9c9fcc32a6acbc8b903c7
https://doi.org/10.1158/2326-6066.22542846
https://doi.org/10.1158/2326-6066.22542846