Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Yongsheng Yuan"'
Autor:
Lina Wang, Huimin Sun, Heng Zhang, Min Ji, Caiting Gan, Aidi Shan, Xingyue Cao, Yongsheng Yuan, Kezhong Zhang
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Addressing levodopa-unresponsive freezing of gait (FOG) in Parkinson’s disease (PD) presents a significant challenge. A randomized double-blinded trial evaluated the effects of repetitive transcranial magnetic stimulation (rTMS) in conjunc
Externí odkaz:
https://doaj.org/article/c05428d1e88847b39ccd5fb2f0e78237
Autor:
Qianling Lu, Zhuang Zhu, Heng Zhang, Caiting Gan, Aidi Shan, Mengxi Gao, Huimin Sun, Xingyue Cao, Yongsheng Yuan, Joseph I. Tracy, Qirui Zhang, Kezhong Zhang
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Neuropsychiatric symptoms (including anxiety, depression, apathy, impulse–compulsive behaviors and hallucinations) are among the most common non-motor features of Parkinson’s disease. Whether these symptoms should be considered as a dire
Externí odkaz:
https://doaj.org/article/cf426b0e32b24d57a54884baa9befd30
Autor:
Xingyue Cao, Caiting Gan, Heng Zhang, Yongsheng Yuan, Huimin Sun, Li Zhang, Lina Wang, Lian Zhang, Kezhong Zhang
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Dilated perivascular spaces (PVS) have emerged as a pathological hallmark in various neurological conditions, including Parkinson’s disease (PD). Levodopa-induced dyskinesia (LID), an intractable motor complication of PD, remains enigmatic
Externí odkaz:
https://doaj.org/article/28340888bcf64e0c83a1111c8784f09f
Autor:
Caiting Gan, Xingyue Cao, Huimin Sun, Shiyi Ye, Jiaxin Shi, Aidi Shan, Mengxi Gao, Chenhui Wan, Kezhong Zhang, Yongsheng Yuan
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106560- (2024)
Background: Impulse control disorders (ICD) in Parkinson's disease (PD) is highly multifactorial in etiology and has intricate neural mechanisms. Our multimodal neuroimaging study aimed to investigate the specific patterns of structure-function-neuro
Externí odkaz:
https://doaj.org/article/4649977ebc414184b6612d2e9201bd82
Autor:
Yangxia Li, Qing Tong, Ye Wang, Yue Cheng, Yao Geng, Tian Tian, Yongsheng Yuan, Yi Fan, Ming Lu, Kezhong Zhang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Despite the significant frequency of autonomic dysfunction (AutD) in Parkinson’s disease (PD) patients, its pathogenesis and diagnosis are challenging. Here, we aimed to further explore the mechanism of phosphorylated α-synuclein (p-α-sy
Externí odkaz:
https://doaj.org/article/cd124dd3b05741169a89e715f04cc45f
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionImpulse control disorders (ICDs) refer to the common neuropsychiatric complication of Parkinson’s disease (PD). The white matter (WM) topological organization and its impact on brain networks remain to be established.MethodsA total of 1
Externí odkaz:
https://doaj.org/article/b43619013bfc4ca68936ac4c7e8ef4ae
Autor:
Caiting Gan, Xingyue Cao, Lina Wang, Huimin Sun, Min Ji, Heng Zhang, Yongsheng Yuan, Kezhong Zhang
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 814-824 (2023)
Abstract Background Mounting research support that cholinergic dysfunction plays a prominent role in freezing of gait (FOG), which commonly occurs in Parkinson's disease (PD). Basal forebrain (BF), especially the cholinergic nuclei 4 (Ch4), provides
Externí odkaz:
https://doaj.org/article/cfebc40d7e9a436f9fe490b5a111fe52
Autor:
Caiting Gan, Min Ji, Huimin Sun, Xingyue Cao, Jiaxin Shi, Lina Wang, Heng Zhang, Yongsheng Yuan, Kezhong Zhang
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106265- (2023)
Background: Freezing of gait (FOG) is an intractable and paroxysmal gait disorder that seriously affects the quality of life of Parkinson's disease (PD) patients. Emerging studies have reported abnormal brain activity of distributed networks in FOG p
Externí odkaz:
https://doaj.org/article/e52c736b8e104c738357aa144c836df9
Autor:
Yue Cheng, Qing Tong, Yongsheng Yuan, Xinna Song, Wenwen Jiang, Yueping Wang, Wenjie Li, Yangxia Li, Kezhong Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Increasing evidence suggests that patients with Parkinson's disease (PD) present with peripheral autonomic dysfunction (AutD) that even precedes motor deficits, through which α-synuclein can spread to the central nervous system.
Externí odkaz:
https://doaj.org/article/2887c478bb27480cba8c28e235d40796
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Impulse control disorders (ICD) in Parkinson’s disease (PD) might be attributed to misestimate of rewards or the failure to curb inappropriate choices. The mechanisms underlying ICD were reported to involve the lateralization of monoamine
Externí odkaz:
https://doaj.org/article/f543fede9cf84311ab2dbc06d1103e78