Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Yongsheng Chang"'
Autor:
Yinliang Zhang, Chunyuan Du, Wei Wang, Wei Qiao, Yuhui Li, Yujie Zhang, Sufang Sheng, Xuenan Zhou, Lei Zhang, Heng Fan, Ying Yu, Yong Chen, Yunfei Liao, Shihong Chen, Yongsheng Chang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The mechanisms underlying glucocorticoid (GC)-induced obesity are poorly understood. Macrophages are the primary targets by which GCs exert pharmacological effects and perform critical functions in adipose tissue homeostasis. Here, we show t
Externí odkaz:
https://doaj.org/article/55509ae258d14b1caa4e019c7d861089
Autor:
Lei Zhang, Jiabing Chen, Xiaoying Yang, Chuangpeng Shen, Jiawen Huang, Dong Zhang, Naihua Liu, Chaonan Liu, Yadi Zhong, Yingjian Chen, Kaijia Tang, Jingyi Guo, Tianqi Cui, Siwei Duan, Jiayu Li, Shangyi Huang, Huafeng Pan, Huabing Zhang, Xiaoqiang Tang, Yongsheng Chang, Yong Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract A lasting imbalance between fatty acid synthesis and consumption leads to non-alcoholic fatty liver disease (NAFLD), coupled with hepatitis and insulin resistance. Yet the details of the underlying mechanisms are not fully understood. Here,
Externí odkaz:
https://doaj.org/article/d8de1c3c1c394317ae7c9862f20a043f
Autor:
Lei Zhang, Qing Zhang, Da Teng, Manyu Guo, Kechao Tang, Zhenglin Wang, Xiang Wei, Li Lin, Xiaomin Zhang, Xiuyun Wang, Dake Huang, Cuiping Ren, Qingsong Yang, Wenjun Zhang, Yong Gao, Wei Chen, Yongsheng Chang, Huabing Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Most nonalcoholic steatohepatitis (NASH) patients develop severe fibrosis through extracellular matrix (ECM) accumulation, which can lead to hepatocellular carcinoma (HCC). Fibroblast growth factor 9 (FGF9) is involved in serial types of can
Externí odkaz:
https://doaj.org/article/a5a76fa84c0e478abbf0d508bd328e5f
Publikováno v:
Separations, Vol 10, Iss 12, p 595 (2023)
Cyanobacterial blooms in freshwater bodies are mainly attributed to the excess loading of nutrients. The microbes in sediments may affect nutrient migration and transformation during the growth of cyanobacteria. This study focused on the role of Para
Externí odkaz:
https://doaj.org/article/cc9974a41dee46eca93183156b5f97c2
Autor:
Tongtong Qiu, Xin Yang, Jingzhou Wang, Chongge Pan, Xiaolong Chu, Jianyu Xiong, Jianxin Xie, Yongsheng Chang, Cuizhe Wang, Jun Zhang
Publikováno v:
Nutrition & Diabetes, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Objective Our previous results have shown that obesity-induced excessive palmitic acid (PA) can promote the expression of KLF7, which plays a vital role in regulation of inflammation, glucose metabolism. But the exact mechanism of PA up-regu
Externí odkaz:
https://doaj.org/article/15629e668e8d48ec86476bd5ece7a5c6
Autor:
Chongge Pan, Menghuan Li, Jingzhou Wang, Xiaolong Chu, Jianyu Xiong, Xin Yang, Yihan Tang, Dingling Ma, Chenggang Yuan, Jiaojiao Zhu, Yongsheng Chang, Jun Zhang, Cuizhe Wang
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 4, Pp 617-627 (2022)
Abstract Aim/Introduction Obesity is considered an important risk factor for many metabolic disorders, especially type 2 diabetes mellitus, and microRNAs (miRNAs) play a vital role in the development of type 2 diabetes mellitus. Therefore, we conduct
Externí odkaz:
https://doaj.org/article/06cb1f19d8024ffba81abc4d35041288
Publikováno v:
Separations, Vol 10, Iss 10, p 535 (2023)
Sediment bacterial communities are a vital component of microbial communities in aquatic and terrestrial ecosystems and they play a critical role in lake wetlands. We aimed to investigate the effect of season, depth and regional environmental factors
Externí odkaz:
https://doaj.org/article/b648c2de117e432b8fd19dce99a98e7c
Autor:
Cuizhe Wang, Xiaolong Chu, Yuchun Deng, Jingzhou Wang, Tongtong Qiu, Jiaojiao Zhu, Xin Yang, Chongge Pan, Jianyu Xiong, Jianxin Xie, Yongsheng Chang, Jun Zhang
Publikováno v:
Nutrition & Metabolism, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Obesity-induced elevated serum free fatty acids (FFAs) levels result in the occurrence of type 2 diabetes mellitus (T2DM). However, the molecular mechanism remains largely enigmatic. This study was to explore the effect and mechan
Externí odkaz:
https://doaj.org/article/10c6f0560c7643fba4fc7c3d18873695
Autor:
Xiaolong Chu, Yanting Hou, Xueting Zhang, Menghuan Li, Dingling Ma, Yihan Tang, Chenggang Yuan, Chaoyue Sun, Maodi Liang, Jie Liu, Qianqian Wei, Yongsheng Chang, Cuizhe Wang, Jun Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2964 (2023)
The present study aimed to explore the molecular mechanism underlying the regulation of glucose metabolism by miR-548ag. For the first time, we found that miR-548ag expression was elevated in the abdominal adipose tissue and serum of subjects with ob
Externí odkaz:
https://doaj.org/article/d3d41dd0a5af40f991c1cacc8226c1da
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Although the fatty liver has been linked to numerous impairments of energy homeostasis, the molecular mechanism responsible for fatty liver development remains largely unknown. In the present study, we show that fibroblast growth factors 9 (FGF9) exp
Externí odkaz:
https://doaj.org/article/79e2a902ef93467cb57975a7c46ddf54