Výsledky vyhledávání - "Yongmu, Zheng"

Generation of a human urinary bladder smooth muscle cell line

Autor: S. Bruce Malkowicz, Sandra Burkett, Ettickan Boopathi, Shaohua Chang, Samuel Chacko, Yongmu Zheng, Mary John

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 48:84-96

We report a cell line (hBSM) established from human urinary bladder wall smooth muscle that maintains most of the phenotypic characteristics of smooth muscle cells. Cells were dissociated from the muscular layer with collagenase (1 mg/ml) and collect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760e207534e9d0f96baa312aa0c18ae5
https://doi.org/10.1007/s11626-011-9473-9

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Over Expression of Smooth Muscle Specific Caldesmon by Transfection and Intermittent Agonist Induced Contraction Alters Cellular Morphology and Restores Differentiated Smooth Muscle Phenotype

Autor: Aseem R. Shukla, Trang Nguyen, Yongmu Zheng, Stephen A. Zderic, Alan J. Wein, Samuel Chacko, Michael E. DiSanto

Publikováno v: Journal of Urology. 171:1949-1954

The thin filament associated protein h-caldesmon (h-CaD) modulates actin myosin interaction and contraction. Bladder outlet obstruction and detrusor hypertrophy are associated with the over expression of the nonmuscle CaD isoform l-CaD. It implies a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3399ed4b6c8e55cf457d694b36e0bfbb
https://doi.org/10.1097/01.ju.0000123061.87723.e9

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Smooth Muscle Hypertrophy Following Partial Bladder Outlet Obstruction Is Associated with Overexpression of Non-Muscle Caldesmon

Autor: Samuel Chacko, Alan J. Wein, Raimund Stein, Stephen A. Zderic, Shaohua Chang, Yongmu Zheng, Erik Zhang

Publikováno v: The American Journal of Pathology. 164:601-612

Partial bladder outlet obstruction (PBOO) induces remodeling of urinary bladder smooth muscle (detrusor). We demonstrate an increase in bladder wall mass, muscle bundle size, and a threefold increase in the cross-sectional area of detrusor myocytes f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f845f4a8b7750f771bc0f1b1f6cc8b1
https://doi.org/10.1016/s0002-9440(10)63149-5

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Alteration in expression of myosin isoforms in detrusor smooth muscle following bladder outlet obstruction

Autor: Michael E. DiSanto, Yongmu Zheng, Alan J. Wein, Joseph A. Hypolite, Shaohua Chang, Samuel Chacko, Raimund Stein, Stephen A. Zderic

Publikováno v: American Journal of Physiology-Cell Physiology. 285:C1397-C1410

Partial urinary bladder outlet obstruction (PBOO) in men, secondary to benign prostatic hyperplasia, induces detrusor smooth muscle (DSM) hypertrophy. However, despite DSM hypertrophy, some bladders become severely dysfunctional (decompensated). Usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db9fe04516aa6e1aa567e261cca06a0
https://doi.org/10.1152/ajpcell.00513.2002

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The TERE1 protein interacts with mitochondrial TBL2: regulation of trans-membrane potential, ROS/RNS and SXR target genes

Autor: William J, Fredericks, Terry, McGarvey, Huiyi, Wang, Yongmu, Zheng, Nathaniel J, Fredericks, Hankun, Yin, Li-Ping, Wang, Wayland, Hsiao, Rob, Lee, Jayne S, Weiss, Michael L, Nickerson, Howard S, Kruth, Frank J, Rauscher, S Bruce, Malkowicz

Publikováno v: Journal of cellular biochemistry. 114(9)

We originally discovered TERE1 as a potential tumor suppressor protein based upon reduced expression in bladder and prostate cancer specimens and growth inhibition of tumor cell lines/xenografts upon ectopic expression. Analysis of TERE1 (aka UBIAD1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f7cac5854b034f7f5feed776d2f10a7
https://pubmed.ncbi.nlm.nih.gov/23564352

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Both the N- and the C-Terminal Domains of the Nominal Phosphoprotein of Rabies Virus Are Involved in Binding to the Nucleoprotein

Autor: Yongmu Zheng, William H. Wunner, Hilary Koprowski, Bernhard Dietzschold, Zhen Fang Fu

Publikováno v: Virology. 200:590-597

The interaction of the nominal phosphoprotein (NS) and the nucleoprotein (N) of rabies virus (Evelyn Rokitnicki Abelseth strain) was investigated by expressing these proteins in insect cells and in an in vitro coupled transcription-translation system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5dfdf9deee470e27933517b3258bc5
https://doi.org/10.1006/viro.1994.1222

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Generation of a cell line with smooth muscle phenotype from hypertrophied urinary bladder

Autor: Michael E. DiSanto, Shuqin Wang, Samuel Chacko, Wilfried Weber, Yongmu Zheng, Stephen A. Zderic, Alan J. Wein

Publikováno v: American journal of physiology. Cell physiology. 283(1)

We have established a cell line from hypertrophied rabbit urinary bladder smooth muscle (SM) that stably expresses SM myosin (SMM). These cells, termed BSM, are spindle shaped and form swirls, similar to the “hills and valleys” described for cult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477b1f9e91c513fb18ee2cd4ad5191cb
https://pubmed.ncbi.nlm.nih.gov/12055106

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Regional variation in myosin isoforms and phosphorylation at the resting tone in urinary bladder smooth muscle

Autor: Alan J. Wein, Samuel Chacko, Yongmu Zheng, Michael E. DiSanto, Joseph A. Hypolite, Shaohua Chang

Publikováno v: American journal of physiology. Cell physiology. 280(2)

Urinary bladder filling and emptying requires coordinated control of bladder body and urethral smooth muscles. Bladder dome, midbladder, base, and urethra showed significant differences in the percentage of 20-kDa myosin light chain (LC20) phosphoryl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db27783e67beead9c00bf1cec2077052
https://pubmed.ncbi.nlm.nih.gov/11208519

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