Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Yongmei Xie"'
Autor:
Yunxiao Du, Guobin Li, Xinglin Li, Xiaohong Jian, Xiaoling Wang, Yongmei Xie, Zaixin Li, Zhi Zhang
Publikováno v:
International Dental Journal, Vol 74, Iss 6, Pp 1298-1305 (2024)
Objective: The purpose of this work was to develop an anti-CAT-SYI immunoglobulin Y (IgY) antibody that targeted both GtfB (glucosyltransferase B) and GbpB (glucan-binding protein B) and test its anticaries properties in rats. Methods: A new CAT-SYI
Externí odkaz:
https://doaj.org/article/47c6cf8773e04ce69d93ae62f789f0b9
Autor:
Xing Lan, Shugang Qin, Huan Liu, Mengran Guo, Yupei Zhang, Xinyang Jin, Xing Duan, Min Sun, Zhenjun Liu, Wenyan Wang, Qian Zheng, Xuelian Liao, Jinpeng Chen, Yan Kang, Yongmei Xie, Xiangrong Song
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) is a formidable pathogen responsible for severe intracranial infections post-craniotomy, exhibiting a mortality rate as high as 71%. Tigecycline (TGC), a broad-spectrum antibio
Externí odkaz:
https://doaj.org/article/0d9c988c5b3c425da0bc59d4aca7286b
Autor:
Dongping Yao, Ting Li, Lu Yu, Mingxing Hu, Ye He, Ruiming Zhang, Junjie Wu, Shuoyuan Li, Weihong Kuang, Xifei Yang, Gongping Liu, Yongmei Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Alzheimer’s disease (AD) is one of the most common chronic neurodegenerative diseases. Hyperphosphorylated tau plays an indispensable role in neuronal dysfunction and synaptic damage in AD. Proteolysis-targeting chimeras (PROTACs) are a novel type
Externí odkaz:
https://doaj.org/article/9651772fcd3f4f64907ab291d0a521db
Publikováno v:
Medicina, Vol 60, Iss 10, p 1646 (2024)
Background and Objectives: The proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab are recently developed promising drugs used for treatment of familial hypercholesterolemia (FH). This systematic review and meta
Externí odkaz:
https://doaj.org/article/645c168d4fb645fcabf6ef7f9c6e8dad
Autor:
Ruiming Zhang, Chuanyue Gao, Mingxing Hu, Xingxing Wang, Shuoyuan Li, Zhenmei An, Xifei Yang, Yongmei Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Chrysin (5,7-dihydroxyflavone) is a natural flavonoid that has been reported as a potential treatment for non-alcoholic fatty liver disease (NAFLD). However, extensive phase II metabolism and poor aqueous solubility led to a decrease in t
Externí odkaz:
https://doaj.org/article/72d154c123ff4809afe2ebf87ad5ab24
Autor:
Kaiwu He, Lulin Nie, Tahir Ali, Zizhen Liu, Weifen Li, Ruyan Gao, Zena Zhang, Jianjun Liu, Zhongliang Dai, Yongmei Xie, Zaijun Zhang, Gongping Liu, Ming Dong, Zhi-Jian Yu, Shupeng Li, Xifei Yang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background A wide spectrum of changes occurs in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunction is one of the significant factors associated with age. Adiponectin (APN), a
Externí odkaz:
https://doaj.org/article/bef7bd9f1a1e4a68bb8431eaa56116a4
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1530de8d4d1449ef8c827c7993df686e
Autor:
Zi Liu, Mingxing Hu, Yu Yang, Chenghao Du, Haoxuan Zhou, Chengyali Liu, Yuanwei Chen, Lei Fan, Hongqun Ma, Youling Gong, Yongmei Xie
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-26 (2022)
Abstract Proteolysis targeting chimeras (PROTACs) technology has emerged as a novel therapeutic paradigm in recent years. PROTACs are heterobifunctional molecules that degrade target proteins by hijacking the ubiquitin–proteasome system. Currently,
Externí odkaz:
https://doaj.org/article/efe35c610f0c47d9bb039742f40b9e4b
Autor:
Chongyang Chen, Jing Wang, Chao Yang, Haitao Yu, Bingge Zhang, Xiao Yang, Bocheng Xiong, Yongmei Xie, Shupeng Li, Zaijun Zhang, Feiqi Zhu, Jianjun Liu, Gong‐Ping Liu, Xifei Yang
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Sleep insufficiency is associated with various disorders; the molecular basis is unknown until now. Here, 14 males and 18 females were subjected to short‐term (24 h) sleep deprivation, and donated fasting blood samples prior to (day 1) and
Externí odkaz:
https://doaj.org/article/c1e9cd426ecf4061877324d3f5fa0c82
Autor:
Jing Zhou, Rongce Zhao, Haoxuan Zhou, Shuping Yang, Feiyan Tao, Yongmei Xie, Hongli Wang, Jingping Yun
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Colorectal cancer (CRC) is one of the most common malignancies causing the third highest mortality rate in the world. It is particularly urgent to explore effective therapeutic strategies to overcome this disease. We identified a novel be
Externí odkaz:
https://doaj.org/article/c4d01aec8c77432eaa657e7dfd78b046