Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Yongmei, Feng"'
Autor:
Yongmei Feng, Stefan Grotegut, Predrag Jovanovic, Valentina Gandin, Steven H. Olson, Rabi Murad, Anne Beall, Sharon Colayco, Paul De-Jesus, Sumit Chanda, Brian P. English, Robert H. Singer, Michael Jackson, Ivan Topisirovic, Ze’ev A. Ronai
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis. Alterations in eIF4F activity are linked to several diseases, including cancer and infectious diseases. To this end, coronaviruses require eIF4F complex act
Externí odkaz:
https://doaj.org/article/3f5893fb1bab4b94b39dab0daec38624
Autor:
Ali Khateb, Anagha Deshpande, Yongmei Feng, Darren Finlay, Joo Sang Lee, Ikrame Lazar, Bertrand Fabre, Yan Li, Yu Fujita, Tongwu Zhang, Jun Yin, Ian Pass, Ido Livneh, Irmela Jeremias, Carol Burian, James R. Mason, Ronit Almog, Nurit Horesh, Yishai Ofran, Kevin Brown, Kristiina Vuori, Michael Jackson, Eytan Ruppin, Aniruddha J. Deshpande, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Epigenetic changes are implicated in Acute myeloid leukemia (AML) tumorigenesis. Here, the authors show that the ubiquitin ligase RNF5 and its substrate RBBP4 contribute to AML development by regulating epigenetic-controlled transcription which deter
Externí odkaz:
https://doaj.org/article/906878f0ea8448bb9623f72fa90b2362
Autor:
Marzia Scortegagna, Kathryn Hockemeyer, Igor Dolgalev, Joanna Poźniak, Florian Rambow, Yan Li, Yongmei Feng, Roberto Tinoco, Dennis C. Otero, Tongwu Zhang, Kevin Brown, Marcus Bosenberg, Linda M. Bradley, Jean-Christophe Marine, Ioannis Aifantis, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The ubiquitin ligase Siah2 has been implicated in immune responses. Here, the authors show that Siah2 null immune cells have an increased inflammatory response to inoculated melanoma cells, along with a reduced number of infiltrating immunosuppressiv
Externí odkaz:
https://doaj.org/article/b4571c9b4e094486a2056a1668569d65
Autor:
Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
RNF5 is a ubiquitin ligase regulating ER stress response. Here the authors show that Rnf5 deficiency potentiates immune response against melanoma via altered microbiota, and isolate bacterial strains that confer the same phenotype to wild type mice.
Externí odkaz:
https://doaj.org/article/47e63127b17f4776963dab1e5a8faa8f
Autor:
Yan Li, Lisa Elmén, Igor Segota, Yibo Xian, Roberto Tinoco, Yongmei Feng, Yu Fujita, Rafael R. Segura Muñoz, Robert Schmaltz, Linda M. Bradley, Amanda Ramer-Tait, Raphy Zarecki, Tao Long, Scott N. Peterson, Ze’ev A. Ronai
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1753-1766.e6 (2020)
Summary: Growing evidence supports the importance of gut microbiota in the control of tumor growth and response to therapy. Here, we select prebiotics that can enrich bacterial taxa that promote anti-tumor immunity. Addition of the prebiotics inulin
Externí odkaz:
https://doaj.org/article/514aa5afbc774f0dad63305d1537f92d
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Bacteria possess a diverse collection of CRISPR-Cas systems but many do not function in mammalian cells, precluding their use in genome editing. Here the authors show that by manipulating local chromatin structures, inhibited Cas9s can have their act
Externí odkaz:
https://doaj.org/article/ee1963f9ae8643bcaf0eb11a40952e78
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Movie S2 - 3D representation around the X axis of A375 cell nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60119b9cd9051aa56714235d7edefb69
https://doi.org/10.1158/1541-7786.22525869
https://doi.org/10.1158/1541-7786.22525869
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Table S1: Clinical information related to the PDX used in Fig1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f75bcacd37d2cbb759a6ca9388ba6a3
https://doi.org/10.1158/1541-7786.22525866.v1
https://doi.org/10.1158/1541-7786.22525866.v1
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplemental Methods, Figures, Figure legends, Table and Movie Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058efe371d19894180d9514ec84de5fe
https://doi.org/10.1158/1541-7786.22525875
https://doi.org/10.1158/1541-7786.22525875
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Movie S1 - 3D representation around the Y axis of A375 cell nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07124d82b28343054cafa9ec742a937b
https://doi.org/10.1158/1541-7786.22525872.v1
https://doi.org/10.1158/1541-7786.22525872.v1