Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yongling Zhu"'
Autor:
Andrew Jo, Sercan Deniz, Suraj Cherian, Jian Xu, Daiki Futagi, Steven H. DeVries, Yongling Zhu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Neural computations arise from highly precise connections between specific types of neurons. Retinal ganglion cells (RGCs) with similar stratification patterns are positioned to receive similar inputs but often display different response pro
Externí odkaz:
https://doaj.org/article/130748b45567441cad1eed120b64d759
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A fundamental organizing plan of the retina is that visual information is divided into ON and OFF streams that are processed in separate layers. This functional dichotomy originates in the ON and OFF bipolar cells, which then make excitatory
Externí odkaz:
https://doaj.org/article/fc436c733d154616882b6dfd0dc11e46
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101907- (2022)
Summary: Although it is now known that certain neurons can produce, store, and release multiple neurotransmitters, their locations, abundance, and functions remain elusive. We developed intersectional genetic strategies to identify multi-transmitter
Externí odkaz:
https://doaj.org/article/cf6da2b0ab4e4dccb696d8932ae2eab7
Autor:
Jian Xu, Andrew Jo, Raina P. DeVries, Sercan Deniz, Suraj Cherian, Idris Sunmola, Xingqi Song, John J. Marshall, Katherine A. Gruner, Tanya L. Daigle, Anis Contractor, Talia N. Lerner, Hongkui Zeng, Yongling Zhu
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111036- (2022)
Summary: Recent developments in intersectional strategies have greatly advanced our ability to precisely target brain cell types based on unique co-expression patterns. To accelerate the application of intersectional genetics, we perform a brain-wide
Externí odkaz:
https://doaj.org/article/517262693797456c85fe96bde305a1a9
Autor:
Jian Xu, Yongling Zhu
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background The LoxP site based genetic switch, the FLEX, also known as DIO (Double-Floxed Inverted Open reading frame), was invented to turn on gene expression via Cre-mediated recombination. Since its first publication, numerous FLEX switch
Externí odkaz:
https://doaj.org/article/cacbda2a23e3404abdb8d96af13bcd42
Autor:
Jian Xu, John J. Marshall, Herman B. Fernandes, Toshihiro Nomura, Bryan A. Copits, Daniele Procissi, Susumu Mori, Lei Wang, Yongling Zhu, Geoffrey T. Swanson, Anis Contractor
Publikováno v:
Cell Reports, Vol 18, Iss 8, Pp 1848-1857 (2017)
Kainate receptors are members of the glutamate receptor family that regulate synaptic function in the brain. They modulate synaptic transmission and the excitability of neurons; however, their contributions to neural circuits that underlie behavior a
Externí odkaz:
https://doaj.org/article/7f00d702d31343d6b0ff4c947dde9931
Publikováno v:
Cell Reports, Vol 13, Iss 12, Pp 2663-2670 (2015)
Decades of research have focused on the circuit connectivity between retinal neurons, but only a handful of amacrine cells have been described functionally and placed in the context of a specific retinal circuit. Here, we identify a circuit where inh
Externí odkaz:
https://doaj.org/article/edb8f9c77ce44d9b84ff0233e31e0606
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
The mammalian retina harbors over 100 different cell types. To understand how retinal circuits work, it is essential to systematically access each type. A widely used approach for achieving targeted transgene expression exploits promoter-driven Cre l
Externí odkaz:
https://doaj.org/article/254f195f03ee4c7e916264483221857f
Autor:
Quanke, Su, Yongling, Zhu, Yue, Chen, Lei, Fang, Yu, Yan, Zongxian, Su, de Wit, Hans, Ying, Li
Publikováno v:
In Tunnelling and Underground Space Technology incorporating Trenchless Technology Research March 2022 121
Publikováno v:
IABSE Congress, Nanjing 2022: Bridges and Structures: Connection, Integration and Harmonisation.
The Hong Kong–Zhuhai–Macao Bridge (HZMB) located at the Pearl River Estuary on the south coast of China, links Hong Kong in the east with Zhuhai-Macao in the west with a total length of 55 km; It is the longest sea-crossing made of artificial isl