Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yonglie Ma"'
Publikováno v:
Translational Stroke Research
Cerebral collateral circulation and age are critical factors in determining outcome from acute ischemic stroke. Aging may lead to rarefaction of cerebral collaterals, and thereby accelerate ischemic injury by reducing penumbral blood flow. Dynamic ch
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Circulation through cerebral collaterals can maintain tissue viability until reperfusion is achieved. However, collateral circulation is time limited, and failure of collaterals is accelerated in the aged. Remote ischemic perconditioning (RIPerC), wh
Autor:
Frederick Colbourne, Ian R. Winship, Yonglie Ma, Cassandra M. Wilkinson, Anna C J Kalisvaart, Tiffany F. C. Kung
Publikováno v:
Stroke. 51
Background: Raised intracranial pressure (ICP) following severe strokes can impede blood flow to the brain, causing injury or death. There are compensatory mechanisms regulating ICP, but they are often inadequate. Interestingly, our recent observatio
Examining potential side effects of therapeutic hypothermia in experimental intracerebral hemorrhage
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:2975-2986
Studies treating intracerebral hemorrhage (ICH) with therapeutic hypothermia (TH) have shown inconsistent benefits. We hypothesized that TH’s anti-inflammatory effects may be responsible as inflammatory cells are essential for removing degrading er
Publikováno v:
Translational Stroke Research. 4:719-728
Iron chelators, such as the intracellular ferrous chelator 2,2'-bipyridine, are a potential means of ameliorating iron-induced injury after intracerebral hemorrhage (ICH). We evaluated bipyridine against the collagenase and whole-blood ICH models and
Collateral circulation is a key variable determining prognosis and response to recanalization therapy during acute ischemic stroke. Remote ischemic perconditioning (RIPerC) involves inducing peripheral ischemia (typically in the limbs) during stroke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e37fad90dcf1470a0ce80c67698d48a
https://europepmc.org/articles/PMC5536804/
https://europepmc.org/articles/PMC5536804/
Publikováno v:
Therapeutic hypothermia and temperature management. 6(1)
Intracerebral hemorrhage (ICH) is often a devastating stroke, and there are no clinically proven neuroprotective treatments. Considerable research points to iron toxicity as a leading contributor to secondary damage after ICH. Iron, released from deg
Autor:
Lucia Secchia, Yonglie Ma, Gregory D. Funk, Betty Y. Poon, Klaus Ballanyi, Araya Ruangkittisakul, Stephan W. Schwarzacher
Publikováno v:
The Journal of Neuroscience. 26:11870-11880
The pre-Bötzinger complex (PBC) inspiratory center remains active in a transverse brainstem slice. Such slices are studied at high (8–10 mm) superfusate [K+], which could attenuate the sensitivity of the PBC to neuromodulators such as opiates. Fin
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. 41(6)
Background: Brain injury after intracerebral hemorrhage (ICH) arises from numerous contributors, of which some also play essential roles. Notably, thrombin production, needed to stop bleeding, also causes acute cell death and edema. In some rodent mo