Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yongliang Fang"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 8, Pp 3255-3262 (2022)
T cells, including both CD4+ and CD8+ T cells, play a pivotal role in mediating various inflammation and immune disorders. A long-standing challenge in T cell-based immunotherapy is to precisely inactivate or delete the pathogenic T cells in inflamma
Externí odkaz:
https://doaj.org/article/91a7270b08924401b1cdcd24a22d9cc6
Autor:
Weixiang Zhong, Yimin Lu, Zhe Ma, Yinjun He, Yongfeng Ding, Gaofeng Yao, Zhenxing Zhou, Jiali Dong, Yongliang Fang, Weiqin Jiang, Weilin Wang, Yanshan Huang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Claudin 18.2 (CLDN18.2), a tight junction (TJ) family protein controlling molecule exchange between cells, is frequently over-expressed in gastric cancer, pancreatic adenocarcinomas and in a fraction of non–small cell lung cancer cases. The tumor p
Externí odkaz:
https://doaj.org/article/d5eec6b91d06499986dfe77b805075dc
Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa
Autor:
Laura Bricio-Moreno, Victoria H. Sheridan, Ian Goodhead, Stuart Armstrong, Janet K.L. Wong, Elaine M. Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E. Griswold, Craig Winstanley, Joanne L. Fothergill, Aras Kadioglu, Daniel R. Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Mutations in gene pmrB are found in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Here, Bricio-Moreno et al. show in a mouse model of respiratory infection that the mutations enhance bacterial adherence to epithelial cells and resist
Externí odkaz:
https://doaj.org/article/dc57b3200e764343a7284314e6587068
Autor:
Bingzheng Shen, Yan Yu, Hui Chen, Xin Cao, Xingzhen Lao, Yongliang Fang, Yun Shi, Jiao Chen, Heng Zheng
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62955 (2013)
New Delhi metallo-β-lactmase-1 (NDM-1) has recently attracted extensive attention for its biological activities to catalyze the hydrolysis of almost all of β-lactam antibiotics. To study the catalytic property of NDM-1, the steady-kinetic parameter
Externí odkaz:
https://doaj.org/article/4d2a33edf2154ec1bc4a2e99cb5063a9
Autor:
Yongliang Fang, Andrew Y. Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R. Davis, Min Dong, Chris Bailey-Kellogg, Karl E. Griswold
Publikováno v:
ACS Synthetic Biology. 12:153-163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::683e8d2e4353ba2456e78c96131b41c2
https://doi.org/10.1021/acssynbio.2c00426
https://doi.org/10.1021/acssynbio.2c00426
Autor:
Yongliang Fang, Ronghua Ye
Publikováno v:
International Conference on Mechanisms and Robotics (ICMAR 2022).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdd443474f24db875c2c4a3ae0b5dbb8
https://doi.org/10.1117/12.2652244
https://doi.org/10.1117/12.2652244
Autor:
Yongliang Fang, Gaofeng Yao, Weixiang Zhong, Wenwen Duan, Zhenxing Zhou, Xiaofang Wen, Yonglu Chen, Jingjin Fang, Yongwei Wang, Weiqin Jiang, Junfang Xu, Yanshan Huang
Publikováno v:
Cancer Research. 82:2857-2857
Claudin 18.2 (CLDN18.2) is aberrantly overexpressed in gastric cancer, pancreatic adenocarcinomas, and a fraction of non-small cell lung cancer. Its tumor specificity allows CLDN18.2 to be an attractive target for developing biotherapeutics for the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44d0234c89304c3601dcf82a673d2bc
https://doi.org/10.1158/1538-7445.am2022-2857
https://doi.org/10.1158/1538-7445.am2022-2857
Autor:
Hongliang Zhao, Yan Q. Xiong, Susan K. Eszterhas, Cynthia Tan, Seth A. Brooks, Karl E. Griswold, Jack R Kirsch, Spencer Heim, Hao D. Cheng, Liang Li, Yongliang Fang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
There is an urgent need for novel agents to treat drug-resistant bacterial infections, such as multidrug-resistant Staphylococcus aureus (MRSA). Desirable properties for new antibiotics include high potency, narrow species selectivity, low propensity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8410da44aa7c0ab6aec56207116012
https://doi.org/10.1128/aac.01707-20
https://doi.org/10.1128/aac.01707-20
Autor:
Yongliang, Fang, Jack R, Kirsch, Liang, Li, Seth A, Brooks, Spencer, Heim, Cynthia, Tan, Susan, Eszterhas, Hao D, Cheng, Hongliang, Zhao, Yan Q, Xiong, Karl E, Griswold
Publikováno v:
Antimicrob Agents Chemother
There is an urgent need for novel agents to treat drug-resistant bacterial infections, such as multidrug-resistant Staphylococcus aureus (MRSA). Desirable properties for new antibiotics include high potency, narrow species selectivity, low propensity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::748b696494034c8542803542c003fc58
https://pubmed.ncbi.nlm.nih.gov/33318001
https://pubmed.ncbi.nlm.nih.gov/33318001
Autor:
Hongliang Zhao, Seth A. Brooks, Yongliang Fang, Jack R Kirsch, Chris Bailey-Kellogg, Yan Q. Xiong, Karl E. Griswold, Deeptak Verma, Susan K. Eszterhas, Spencer Heim, Liang Li
Publikováno v:
Science Advances
A deimmunized lysostaphin biotherapy evades detrimental antidrug immune reactions and has improved efficacy for MRSA infections.
There is a critical need for novel therapies to treat methicillin-resistant Staphylococcus aureus (MRSA) and other d
There is a critical need for novel therapies to treat methicillin-resistant Staphylococcus aureus (MRSA) and other d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c608918fca32c7395d894ff5f3854e6b
https://pubmed.ncbi.nlm.nih.gov/32917596
https://pubmed.ncbi.nlm.nih.gov/32917596