Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Yongli Shan"'
Autor:
Yongli Shan, Yanqi Zhang, Yanxing Wei, Cong Zhang, Huaisong Lin, Jiangping He, Junwei Wang, Wenjing Guo, Heying Li, Qianyu Chen, Tiancheng Zhou, Qi Xing, Yancai Liu, Jiekai Chen, Guangjin Pan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nucleoli are fundamentally essential sites for ribosome biogenesis in cells and formed by liquid-liquid phase separation (LLPS) for a multilayer condensate structure. How the nucleoli integrity is maintained remains poorly understood. Here,
Externí odkaz:
https://doaj.org/article/57e4c749c6af4bab8b295c8b88926ab3
Autor:
Yueli Yang, Wenqi Jia, Zhiwei Luo, Yunpan Li, Hao Liu, Lixin Fu, Jinxiu Li, Yu Jiang, Junjian Lai, Haiwei Li, Babangida Jabir Saeed, Yi Zou, Yuan Lv, Liang Wu, Ting Zhou, Yongli Shan, Chuanyu Liu, Yiwei Lai, Longqi Liu, Andrew P. Hutchins, Miguel A. Esteban, Md. Abdul Mazid, Wenjuan Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract In contrast to rodents, the mechanisms underlying human trophectoderm and early placenta specification are understudied due to ethical barriers and the scarcity of embryos. Recent reports have shown that human pluripotent stem cells (PSCs) c
Externí odkaz:
https://doaj.org/article/08817780a70c41359211caaeee9279c6
Autor:
Ying Jin, Xiaoyu An, Binchen Mao, Ruilin Sun, Rajendra Kumari, Xiaobo Chen, Yongli Shan, Mingfa Zang, Ling Xu, Jan Muntel, Kristina Beeler, Roland Bruderer, Lukas Reiter, Sheng Guo, Demin Zhou, Qi-Xiang Li, Xuesong Ouyang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Cancers are immunologically heterogeneous. A range of immunotherapies target abnormal tumor immunity via different mechanisms of actions (MOAs), particularly various tumor-infiltrate leukocytes (TILs). We modeled loss of function (LOF) in fo
Externí odkaz:
https://doaj.org/article/f458fcf37994447d8b6641e56cd067f3
Autor:
Cong Zhang, Huaisong Lin, Yanqi Zhang, Qi Xing, Jingyuan Zhang, Di Zhang, Yancai Liu, Qianyu Chen, Tiancheng Zhou, Junwei Wang, Yongli Shan, Guangjin Pan
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105939- (2023)
Summary: Post-translational modifications (PTMs) on histones play essential roles in cell fate decisions during development. However, how these PTMs are recognized and coordinated remains to be fully illuminated. Here, we show that BRPF1, a multi-his
Externí odkaz:
https://doaj.org/article/e5abfe432a2f4f08bc0fd2c0ef3495d8
Autor:
Yuan Zhao, Tianyu Wang, Yanqi Zhang, Liang Shi, Cong Zhang, Jingyuan Zhang, Jiao Yao, Qianyu Chen, Xiaofen Zhong, Yanxing Wei, Yongli Shan, Guangjin Pan
Publikováno v:
Cell Regeneration, Vol 10, Iss 1, Pp 1-13 (2021)
Abstract Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this study, by employing an array of diff
Externí odkaz:
https://doaj.org/article/2e8403b28ef746ae845f20e6e16e92b1
Autor:
Yanxing Wei, Lu Xiao, Lishi Ma, Zhijian Wang, Liping Huang, Huiying Li, Guangjin Pan, Stephen J. Lye, Yongli Shan
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101638- (2022)
Summary: Human trophoblast stem cells (hTSCs) are useful for studying human placenta development and diseases, but primed human pluripotent stem cells (hPSCs) routinely cultured in most laboratories do not support hTSC derivation. Here, we present a
Externí odkaz:
https://doaj.org/article/75fae50b255b4a1f94704fd5fdc2f25c
Publikováno v:
Stem Cell Research, Vol 62, Iss , Pp 102803- (2022)
RYBP, a critical component of polycomb repressive complex1 (PRC1), is required for the pluripotency and differentiation of mouse embryonic stem cells(mESCs). However, its function and mechanism to regulate human embryonic stem cells(hESCs) remain unk
Externí odkaz:
https://doaj.org/article/9dc8c1f4d9454835b70abfb8b573969c
Publikováno v:
Stem Cell Research, Vol 62, Iss , Pp 102809- (2022)
RNF1 (RING1A) is a catalytic component of the polycomb repressive complex 1 (PRC1) involved in regulation of, among others, embryonic development and disease progression. However, the exact role of RNF1 in self-renewal and differentiation of human em
Externí odkaz:
https://doaj.org/article/4e5db48b36fe403b83dd45740207abe5
Autor:
Yongli Shan, Yanqi Zhang, Yuan Zhao, Tianyu Wang, Jingyuan Zhang, Jiao Yao, Ning Ma, Zechuan Liang, Wenhao Huang, Ke Huang, Tian Zhang, Zhenghui Su, Qianyu Chen, Yanling Zhu, Chuman Wu, Tiancheng Zhou, Wei Sun, Yanxing Wei, Cong Zhang, Chenxu Li, Shuquan Su, Baojian Liao, Mei Zhong, Xiaofen Zhong, Jinfu Nie, Duanqing Pei, Guangjin Pan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Neurogenesis is an ordered transition from pluriptotent cells to neural precursor cells (NPCs) to neurons. Here the authors show that loss of the lysine demethylases JMJD3 and UTX leads reduced DNA accessibility at neurogenesis loci in human NPCs, an
Externí odkaz:
https://doaj.org/article/80505987d5cf4b679818c2110e0c8333
Autor:
Yongli Shan, Zechuan Liang, Lishi Ma, Cong Zhang, Yanqi Zhang, Jingyuan Zhang, Lu Xiao, Yanxing Wei, Yanhong Yu
Publikováno v:
Stem Cell Research, Vol 57, Iss , Pp 102604- (2021)
Externí odkaz:
https://doaj.org/article/67826980959a42b39e5638206cefeddd