Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yongli KONG"'
Autor:
Min Xie, John M. Shelton, Nan Jiang, Jessica Medina, Francisco Altamirano, Dan L. Li, Joseph A. Hill, Cyndi R. Morales, Anwarul Ferdous, Gabriele G. Schiattarella, Geoffrey W Cho, Xiang Luo, Herman I. May, Thomas G. Gillette, Yongli Kong
Publikováno v:
Circ Res
Rationale: Reperfusion injury accounts for up to half of myocardial infarct size, and meaningful clinical therapies targeting it do not exist. We have reported previously that autophagy is reduced during reperfusion and that HDAC (histone deacetylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2566bfc9d250636e8abebbe6b1e5b9
https://pubmed.ncbi.nlm.nih.gov/34111934
https://pubmed.ncbi.nlm.nih.gov/34111934
Autor:
Jana S. Burchfield, Jay W. Schneider, Vishy Lanka, Beverly A. Rothermel, Ashley L Paul, Camille McCallister, Thomas G. Gillette, Yongli Kong, Wei Tan, Joseph A. Hill
Publikováno v:
Journal of Investigative Medicine. 64:50-62
Adipose-derived stem cells (ADSCs) have myocardial regeneration potential, and transplantation of these cells following myocardial infarction (MI) in animal models leads to modest improvements in cardiac function. We hypothesized that pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269278ddfa860ea7258a949a8b115ef8
https://doi.org/10.1136/jim-2015-000018
https://doi.org/10.1136/jim-2015-000018
Autor:
Geoffrey Cho, Michael E. Jessen, Wei Tan, Aslan T. Turer, Zhao V. Wang, John J. Warner, Min Xie, Joseph A. Hill, Herman I. May, Thomas G. Gillette, Zully Pedrozo, Sergio Lavandero, Pavan K. Battiprolu, Yongli Kong, Xiang Luo, Nan Jiang, Cyndi Morales
Publikováno v:
CIRCULATION
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Background— Reperfusion accounts for a substantial fraction of the myocardial injury occurring with ischemic heart disease. Yet, no standard therapies are available targeting reperfusion injury. Here, we tested the hypothesis that suberoylanilide h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48979ac24b0f06d33b6e3c795c9056f
https://doi.org/10.1161/circulationaha.113.002416
https://doi.org/10.1161/circulationaha.113.002416
Autor:
Joseph A. Hill, Frank Madeo, Eugenia Morselli, Naoufal Zamzami, Guido Kroemer, Maria Chiara Maiuri, Mireia Niso-Santano, Federico Pietrocola, Aleksandra Andryushkova, Sabrina Schroeder, Oliver Kepp, Álvaro F. Fernández, Guillermo Mariño, Silvère Durand, Christoph Magnes, Shoaib Ahmad Malik, Tobias Pendl, Frank Sinner, David Enot, Isabelle Martins, Carlos López-Otín, Tobias Eisenberg, Patrice Codogno, Marie Scoazec, Jens S. Andersen, Alexandra Harger, Thomas R. Pieber, Chantal Bauvy, Laura Senovilla, Erika Vacchelli, Yongli Kong, Martin V. Bennetzen
Publikováno v:
Mariño, G, Pietrocola, F, Eisenberg, T, Kong, Y, Malik, S A, Andryushkova, A, Schroeder, S, Pendl, T, Harger, A, Niso-Santano, M, Zamzami, N, Scoazec, M, Durand, S, Enot, D P, Fernández, Á F, Martins, I, Kepp, O, Senovilla, L, Bauvy, C, Morselli, E, Vacchelli, E, Bennetzen, M, Magnes, C, Sinner, F, Pieber, T, López-Otín, C, Maiuri, M C, Codogno, P, Andersen, J S, Hill, J A, Madeo, F & Kroemer, G 2014, ' Regulation of autophagy by cytosolic acetyl-coenzyme A ', Molecular Cell, vol. 53, no. 5, pp. 710-725 . https://doi.org/10.1016/j.molcel.2014.01.016
Acetyl-coenzyme A (AcCoA) is a major integrator of the nutritional status at the crossroads of fat, sugar, and protein catabolism. Here we show that nutrient starvation causes rapid depletion of AcCoA. AcCoA depletion entailed the commensurate reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2ec63e8c50697404d3d215b948b184
Autor:
Guillermo Mariño, Tobias Eisenberg, Yongli Kong, Federico Pietrocola, Frank Madeo, Joseph A. Hill, Guido Kroemer
Publikováno v:
Autophagy. 10:930-932
It has been a longstanding problem to identify specific and efficient pharmacological modulators of autophagy. Recently, we found that depletion of acetyl-coenzyme A (AcCoA) induced autophagic flux, while manipulations designed to increase cytosolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40623cd7ddd2dfd5d453071017265ad9
https://doi.org/10.4161/auto.28235
https://doi.org/10.4161/auto.28235
Autor:
Paul Tannous, Joseph A. Hill, Beverly A. Rothermel, Yongli Kong, Guangrong Lu, Eric N. Olson, Kambeez Berenji
Publikováno v:
Circulation. 113:2579-2588
Background— Recent work has demonstrated the importance of chromatin remodeling, especially histone acetylation, in the control of gene expression in the heart. In cell culture models of cardiac hypertrophy, pharmacological suppression of histone d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d36dadb03dc620973fc6f35ef9a0e7b
https://doi.org/10.1161/circulationaha.106.625467
https://doi.org/10.1161/circulationaha.106.625467
Autor:
Dan Li, Geoffrey W Cho, Joseph A. Hill, Wei Tan, Herman I. May, Thomas G. Gillette, Min Xie, Nan Jiang, Yongli Kong
Publikováno v:
Journal of the American College of Cardiology. 63(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c196f8828e2c02df22c10a669be06a
Autor:
Guo N Huang, Jeffrey E Thatcher, John McAnally, Yongli Kong, Xiaoxia Qi, Wei Tan, J. Michael DiMaio, James F Amatruda, Robert Gerard, Joseph A Hill, Rhonda Bassel-Duby, Eric N Olson
Publikováno v:
Circulation Research. 113
The epicardium encapsulates the heart and functions as a source of multipotent progenitor cells and paracrine factors essential for cardiac development and repair. Injury of the adult heart results in reactivation of epicardial progenitor cells, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b711f3547e20975b3d8b72119dbff2ca
https://doi.org/10.1161/res.113.suppl_1.a011
https://doi.org/10.1161/res.113.suppl_1.a011
Autor:
J. Michael DiMaio, Rhonda Bassel-Duby, Yongli Kong, Guo N. Huang, Joseph A. Hill, James F. Amatruda, Jeffrey E. Thatcher, John McAnally, Wei Tan, Eric N. Olson, Xiaoxia Qi, Robert D. Gerard
Publikováno v:
Science (New York, N.Y.), vol 338, iss 6114
Enhancing Heart Function The epicardium, a protective layer of tissue surrounding the mammalian heart, plays a critical role during embryogenesis because it supplies growth factors and multipotent progenitor cells essential for heart development. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45aef5c68f66b7ea8077f5733dd0e499
https://escholarship.org/uc/item/92p6k3pc
https://escholarship.org/uc/item/92p6k3pc
Autor:
Nan Jiang, Zhao V. Wang, Joseph A. Hill, Beverly A. Rothermel, Pavan K. Battiprolu, Cyndi R. Morales, Yongli Kong, Dian J. Cao, Thomas G. Gillette
Histone deacetylases (HDACs) regulate cardiac plasticity; however, their molecular targets are unknown. As autophagy contributes to pathological cardiac remodeling, we hypothesized that HDAC inhibitors target autophagy. The prototypical HDAC inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cbb2b673a682470f2f71e8bf686c58
https://europepmc.org/articles/PMC3053983/
https://europepmc.org/articles/PMC3053983/