Persistent Nonviral Plasmid Vector in Nasal Tissues Causes False-Positive SARS-CoV-2 Diagnostic Nucleic Acid Tests

Autor: Ingrid A. Beck, Sheila Styrchak, Leslie Miller, Fred Mast, Vladimir Vigdorovich, Winnie Yeung, Daisy Ko, Alyssa Oldroyd, Samantha Hardy, Song Li, John Houck, Yonghou Jiang, Nicholas Dambrauskas, Catherine Darcey, Andrew Raappana, William Selman, D. Noah Sather, John D. Aitchison, Whitney E. Harrington, Lisa M. Frenkel

Publikováno v: Microbiology Spectrum, Vol 10, Iss 6 (2022)

ABSTRACT Biomedical personnel can become contaminated with nonhazardous reagents used in the laboratory. We describe molecular studies performed on nasal secretions collected longitudinally from asymptomatic laboratory coworkers to determine if they

Externí odkaz: https://doaj.org/article/cf5e3aaaf69246148f1a08716589f2ef

Rapid decline of neutralizing antibodies is associated with decay of IgM in adults recovered from mild COVID-19

Autor: Whitney E. Harrington, Olesya Trakhimets, Daniela V. Andrade, Nicholas Dambrauskas, Andrew Raappana, Yonghou Jiang, John Houck, William Selman, Ashton Yang, Vladimir Vigdorovich, Winnie Yeung, Micaela Haglund, Jackson Wallner, Alyssa Oldroyd, Samantha Hardy, Samuel W.A. Stewart, Ana Gervassi, Wes Van Voorhis, Lisa Frenkel, D. Noah Sather

Publikováno v: Cell Reports Medicine, Vol 2, Iss 4, Pp 100253- (2021)

Summary: The fate of protective immunity following mild severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection remains ill defined. Here, we characterize antibody responses in a cohort of participants recovered from mild SARS-CoV-2 in

Externí odkaz: https://doaj.org/article/60c45fb8b96640d78d452e501895eabe

In vitro–ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems

Autor: Anna K. Blakney, Adam B. Little, Yonghou Jiang, Kim A. Woodrow

Publikováno v: Drug Delivery, Vol 24, Iss 1, Pp 582-590 (2017)

Composite delivery systems where drugs are electrospun in different layers and vary the drug stacking-order are posited to affect bioavailability. We evaluated how the formulation characteristics of both burst- and sustained-release electrospun fiber

Externí odkaz: https://doaj.org/article/1b4d0d81de814e6c9992a170244b620b

Multiplex gel-based PCR assay for the simultaneous detection of 5 genotypes of porcine astroviruses

Autor: Qiuya Zhang, Qin Liu, Tanja Opriessnig, Dan Wen, Keda Gu, Yonghou Jiang

Publikováno v: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Porcine astrovirus (PAstV) has been associated experimentally with diarrhea in piglets, but much more knowledge is needed about this virus. PAstV has high genetic variability, and 5 genotypes have been identified, namely PAstV1–5. To obtain informa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ede71cfb7354fccf78e4777ce9f1d3
https://pubmed.ncbi.nlm.nih.gov/36573660

Novel universal primer-pentaplex PCR assay based on chimeric primers for simultaneous detection of five common pig viruses associated with diarrhea

Autor: Yonghou Jiang, Pei Nan, Tanja Opriessnig, Xiaoya Yu, Dan Wen, Qiuya Zhang

Publikováno v: Nan, P, Wen, D, Opriessnig, T, Zhang, Q, Yu, X & Jiang, Y 2021, ' Novel universal primer-pentaplex PCR assay based on chimeric primers for simultaneous detection of five common pig viruses associated with diarrhea ', Molecular and Cellular Probes, vol. 58, 101747 . https://doi.org/10.1016/j.mcp.2021.101747

Viral pathogens associated with diarrhea in pigs include porcine circovirus 2 (PCV2), porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus A (RVA) and C (RVC) among others. In this study, a novel unive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad9d4d3a3e9fdf52e9c1e35bf280b46
https://hdl.handle.net/20.500.11820/ce9367bf-1da7-4fb5-9a41-be9d8421afb5