Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yonghong P. Yang"'
Autor:
Marina L. H. Honing, Ton J. Rabelink, Paul J. Morrison, Yonghong P. Yang, Robert J. Padley, David E. Ballard, Michel L. Hijmering
Publikováno v:
Journal of the American Society of Nephrology. 11:1498-1504
Endothelin (ET-1) acts as a potent vasoconstrictor in the human kidney, and this vasoconstriction could contribute to the ischemia seen in acute renal failure. In animal studies, the vasoactive properties of ET-1 are known to be ET A receptor-and/or
Autor:
Ton J. Rabelink, Robert J. Padley, Amy Y. Grahn, Anton W. M. Van Weerdt, Marina L. H. Honing, Yonghong P. Yang, Marianne C. Verhaar, Paul J. Morrison
Publikováno v:
British Journal of Clinical Pharmacology. 49:562-573
Aims Endothelins (ETs) may play a role in the pathogenesis of a variety of cardiovascular diseases. The present study was designed to investigate the pharmacokinetic and pharmacodynamic effects of the orally active ETA selective receptor antagonist A