Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Yonghe Wu"'
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Background Tumorigenicity represents a critical challenge in stem cell-based therapies requiring rigorous monitoring. Conventional approaches for tumorigenicity evaluation are based on animal models and have numerous limitations. Brain organ
Externí odkaz:
https://doaj.org/article/c0a457e8605d4fd786ff0d529ed4176f
Autor:
Changwen Wang, Meng Sun, Chunxuan Shao, Lisa Schlicker, Yue Zhuo, Yassin Harim, Tianping Peng, Weili Tian, Nadja Stöffler, Martin Schneider, Dominic Helm, Youjun Chu, Beibei Fu, Xiaoliang Jin, Jan-Philipp Mallm, Moritz Mall, Yonghe Wu, Almut Schulze, Hai-Kun Liu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-21 (2024)
Abstract Recent advances in the genomics of glioblastoma (GBM) led to the introduction of molecular neuropathology but failed to translate into treatment improvement. This is largely attributed to the genetic and phenotypic heterogeneity of GBM, whic
Externí odkaz:
https://doaj.org/article/d63afc60087d40eba8fc806d9ff1af6b
Autor:
Jinsen Zhang, Yuan Feng, Guanghao Li, Jianhua Zhang, Xin Zhang, Yi Zhang, Zhiyong Qin, Dongxiao Zhuang, Tianming Qiu, Zhifeng Shi, Wei Zhu, Rui Zhang, Yonghe Wu, Haikun Liu, Dandan Cao, Wei Hua, Ying Mao
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Astrocytoma and glioblastoma (GB) are reclassified subtypes of adult diffuse gliomas based on distinct isocitrate dehydrogenase (IDH) mutation in the fifth edition of the WHO Classification of Tumors of the Central Nervous System. The recurr
Externí odkaz:
https://doaj.org/article/a46094dd4ac44daf83aa303bff56891b
Publikováno v:
Educational Technology & Society, Vol 25, Iss 1, Pp 179-192 (2022)
Three-dimensional (3D) design can improve students’ spatial ability, but the research on the differences of spatial ability development after 3D design training for students with different initial spatial ability is not unified. The ability-as-enha
Externí odkaz:
https://doaj.org/article/317fb42eaa124e018e03cf28b85fd46b
Autor:
Jinsen Zhang, Minjie Fu, Jinfeng Wu, Fengfeng Fan, Xin Zhang, Chunjie Li, Hui Yang, Yonghe Wu, Yiming Yin, Wei Hua
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Juglone has been extensively reported as a natural antitumor pigment. However, it is easy to be oxidized due to active hydroxy in the quinone. Here, we designed some new juglone derivatives, as the hydroxy was replaced by methyl (D1), allyl (D2), but
Externí odkaz:
https://doaj.org/article/e7a6ccf5f6d04d5eb5bc4b2a4db20fea
Autor:
Yonghe Wu, Michael Fletcher, Zuguang Gu, Qi Wang, Barbara Costa, Anna Bertoni, Ka-Hou Man, Magdalena Schlotter, Jörg Felsberg, Jasmin Mangei, Martje Barbus, Ann-Christin Gaupel, Wei Wang, Tobias Weiss, Roland Eils, Michael Weller, Haikun Liu, Guido Reifenberger, Andrey Korshunov, Peter Angel, Peter Lichter, Carl Herrmann, Bernhard Radlwimmer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Glioblastoma is divided into four subtypes based on molecular profiling at the methylome and transcriptome level. Here the authors perform an integrative analysis of these subtypes resulting in the identification of SOX10 whose loss induces a mesench
Externí odkaz:
https://doaj.org/article/50c3ca33473a428aa36c9a52cf6638ef
Publikováno v:
Micromachines, Vol 13, Iss 10, p 1696 (2022)
In this work, a promising dual-gated thin film transistor (TFT) structure has been proposed and introduced in the shift register (SR)-integrated circuits to reduce the rising time. The threshold voltage can be simultaneously changed by the top gate a
Externí odkaz:
https://doaj.org/article/33a1078e32984d2188cfd038ed6b23b3
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Regulation of gene expression through multiple epigenetic components is a highly combinatorial process. Alterations in any of these layers, as is commonly found in cancer diseases, can lead to a cascade of downstream effects on tumor suppressor or on
Externí odkaz:
https://doaj.org/article/a5b565adfc6f48f1bedb2b557ea50ab6
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Background: Fusion genes play an important role in the tumorigenesis of many cancers. Next-generation sequencing (NGS) technologies have been successfully applied in fusion gene detection for the last several years, and a number of NGS-based tools ha
Externí odkaz:
https://doaj.org/article/cc1098c5ab7848de9b902a87e74eb0a8
Publikováno v:
IEEE Transactions on Learning Technologies. :1-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dce53dd62e6a189c8224cebe3023f169
https://doi.org/10.1109/tlt.2023.3263568
https://doi.org/10.1109/tlt.2023.3263568