Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yongcheng Ying"'
Autor:
Han Bok Kwak, Sung-Hee Pi, Hyung-Keun You, Yongcheng Ying, Seong Hwan Kim, Su-Ui Lee, Jiyong Hong, Seong Rim Byeon, Hendrik Luesch
Publikováno v:
ACS Medicinal Chemistry Letters. 2:248-251
Due to their capability of modifying chromatin structure and thereby regulating gene transcription, histone deacetylases (HDACs) have been reported to play important roles in osteogenesis and considered a promising potential therapeutic target for bo
Autor:
Brian K. Law, Yongcheng Ying, Lilibeth A. Salvador, Yanxia Liu, Hendrik Luesch, Jason C. Kwan, Jiyong Hong, Seongrim Byeon
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 335:351-361
Histone deacetylases (HDACs) are validated targets for anticancer therapy as attested by the approval of suberoylanilide hydroxamic acid (SAHA) and romidepsin (FK228) for treating cutaneous T cell lymphoma. We recently described the bioassay-guided i
Publikováno v:
Organic Letters. 10:4021-4024
To characterize largazole's structural requirements for histone deacetylase (HDAC) inhibitory and antiproliferative activities, a series of analogues with modifications to the side chain or 16-membered macrocycle were prepared and biologically evalua
Publikováno v:
Journal of the American Chemical Society. 130:8455-8459
Full details of the concise and convergent synthesis (eight steps, 19% overall yield), its extension to the preparation of a series of key analogues, and the molecular target and pharmacophore of largazole are described. Central to the synthesis of l
Autor:
Yongcheng Ying, Jiyong Hong
Publikováno v:
Tetrahedron Letters. 48:8104-8107
A synthesis of brasilibactin A, a cytotoxic siderophore from the actinomycete of Nocardia brasiliensis, and three unnatural diastereomers of the natural product is described. Four possible diastereomers of the β-hydroxy acid fragment were prepared v
Publikováno v:
Journal of Solid State Chemistry. 177:4163-4166
Nanocrystalline silicon carbide has been prepared via reacting magnesium silicide (Mg2Si) with carbon tetrachloride (CCl4) in an autoclave at 450–600°C. X-ray diffraction patterns of the products can be indexed as the cubic cell of SiC with the la
Publikováno v:
Journal of Materials Research. 18:2359-2363
Nanoscale hollow spheres of amorphous phosphorus nitride (P3N5) were synthesized by reacting PCl3 with NaN3 at 150–250 °C. Transmission electron microscope images show that the hollow spheres have a diameter of 150–350 nm, and the thickness of t
Autor:
Xuefeng Jiang, Yongcheng Ying
Publikováno v:
Stereoselective Organocatalysis: Bond Formation Methodologies and Activation Modes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e295d8787eff91ae356ef31b06c537e1
https://doi.org/10.1002/9781118604755.ch17
https://doi.org/10.1002/9781118604755.ch17
Publikováno v:
ChemInform. 42
The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, an
The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db142f84369078ff3c0d40bcdbcf1631
https://europepmc.org/articles/PMC3107004/
https://europepmc.org/articles/PMC3107004/