Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yongchang Xu"'
Autor:
Lin Zhu, Yongchang Xu, Jingpeng Li, Guoping Lin, Xuezhu Han, Jiaming Yi, Thilini Jayaprada, Zhenchao Zhou, Yiqian Ying, Meizhen Wang
Publikováno v:
Environment International, Vol 190, Iss , Pp 108902- (2024)
Persistent microbial contamination commonly occurs in the environment. However, the characteristics and associated risks remain largely unknown. The coexistence of virulence factor genes (VFGs) and “last-resort” antibiotic resistance genes (LARGs
Externí odkaz:
https://doaj.org/article/b9db6664ee434528bb1ce702ad1576ea
Autor:
Gaoqin Teng, Meng Zhang, YingYing Fu, Xiaoqiang Yang, Yanhua Kang, Qiuying Qin, Ye Jin, Man Huang, Yongchang Xu
Publikováno v:
mSystems, Vol 9, Iss 6 (2024)
ABSTRACT The emergence of nosocomial infections caused by hypervirulent and carbapenem-resistant K. pneumoniae (hv-CRKP) has become a significant public health challenge. The genetic traits of virulence and resistance plasmids in hv-CRKP have been ex
Externí odkaz:
https://doaj.org/article/7b3713e5a77049b39dd6c01b4cb5e099
Autor:
Yu Shi, Qin Cao, Jingdu Sun, Xiaofang Hu, Zhi Su, Yongchang Xu, Huimin Zhang, Lefu Lan, Youjun Feng
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011110 (2023)
Pseudomonas aeruginosa is an opportunistic pathogen that predominantly causes nosocomial and community-acquired lung infections. As a member of ESKAPE pathogens, carbapenem-resistant P. aeruginosa (CRPA) compromises the limited therapeutic options, r
Externí odkaz:
https://doaj.org/article/1ea1cc9cebe84f2ab971e34649ac134e
Autor:
Dingjun Wu, Yongchang Xu, Hai Zhou, Xin Feng, Jianqiang Zhang, Xiyan Pan, Zheng Gao, Rui Wang, Guokun Ma, Li Tao, Hanbin Wang, Jinxia Duan, Houzhao Wan, Jun Zhang, Liangping Shen, Hao Wang, Tianyou Zhai
Publikováno v:
InfoMat, Vol 4, Iss 9, Pp n/a-n/a (2022)
Abstract Photodetectors (PDs) based on perovskite nanowires are among the most promising next‐generation photodetection technologies; however, their poor long‐term stability is the biggest challenge limiting their commercial application. Herein,
Externí odkaz:
https://doaj.org/article/24be4777193c4a4d957da19d657a195f
Autor:
Yongchang Xu, Jie Yang, Weihui Li, Shuaijie Song, Yu Shi, Lihan Wu, Jingdu Sun, Mengyun Hou, Jinzi Wang, Xu Jia, Huimin Zhang, Man Huang, Ting Lu, Jianhua Gan, Youjun Feng
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010615 (2022)
Tuberculosis (TB) is one of the leading infectious diseases of global concern, and one quarter of the world's population are TB carriers. Biotin metabolism appears to be an attractive anti-TB drug target. However, the first-stage of mycobacterial bio
Externí odkaz:
https://doaj.org/article/78642712ffbf41faafa17c856c44ec6a
Autor:
Sitao Zhang, Yongchang Xu, Hongxin Guan, Tao Cui, Yuling Liao, Wenhui Wei, Jun Li, Bachar H. Hassan, Huimin Zhang, Xu Jia, Songying Ouyang, Youjun Feng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Biotin is an essential enzyme cofactor and two pathways for the generation of the biotin precursor pimeloyl-ACP are known. Here, the authors identify and characterize a third pathway for biotin precursor synthesis involving BioZ and they also present
Externí odkaz:
https://doaj.org/article/c80e552cb1354f92b240e8c666740d25
Autor:
Lu Feng, Bin Yang, Yongchang Xu, Yingying Xiong, Fang Wang, Bin Liu, Wen Yang, Ting Yao, Lei Wang
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110614- (2022)
Summary: Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important extracellular human pathogen. The initial adherence of EHEC to host cells is a major cue for transcriptional induction of the locus of enterocyte effacement (LEE) genes to pro
Externí odkaz:
https://doaj.org/article/1dde1d62f06349ba896d7adfa015acf3
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 49-56 (2020)
A growing number of tet(X)-type tigecycline resistance determinants [tet(X1) to tet(X5)] constitutes an expanding family of tetracycline-inactivating enzymes, posing a potential risk to global public health. Here, we report the development of an effi
Externí odkaz:
https://doaj.org/article/db9e4eb765a54fa6bb02b807dff7a747
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109135- (2021)
Summary: An evolving family of mobile colistin resistance (MCR) enzymes is threatening public health. However, the molecular mechanism by which the MCR enzyme as a rare member of lipid A-phosphoethanolamine (PEA) transferases gains the ability to con
Externí odkaz:
https://doaj.org/article/311f33d560aa4922bcfd3997257194df
Autor:
Yongchang Xu, Lan-Lan Zhong, Swaminath Srinivas, Jian Sun, Man Huang, David L. Paterson, Sheng Lei, Jingxia Lin, Xin Li, Zichen Tang, Siyuan Feng, Cong Shen, Guo-Bao Tian, Youjun Feng
Publikováno v:
EBioMedicine, Vol 34, Iss , Pp 139-157 (2018)
Background: Mobilized resistance to colistin is evolving rapidly and its global dissemination poses a severe threat to human health and safety. Transferable colistin resistance gene, mcr-3, first identified in Shandong, China, has already been found
Externí odkaz:
https://doaj.org/article/b3fb1f6cf04f49618a3b3700c42bf7da