Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yongchang Ouyang"'
Autor:
Bingkun Xie, Wei Yang, Yongchang Ouyang, Lichan Chen, Hesheng Jiang, Yuying Liao, D Joshua Liao
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154855 (2016)
Tens of thousands of chimeric RNAs have been reported. Most of them contain a short homologous sequence (SHS) at the joining site of the two partner genes but are not associated with a fusion gene. We hypothesize that many of these chimeras may be te
Externí odkaz:
https://doaj.org/article/8aa23a0b38f44f71907f2cb485cafda0
Publikováno v:
New Journal of Chemistry. 46:23039-23049
Novel polyhedron was prepared for the high-performance electrocatalysis and detection of doxorubicin, leading to the successful doxorubicin sensing in HeLa cell inhibition.
Autor:
Yuting Zhou, Zhongping Liang, Yingjie Xia, Shuai Li, Jiali Liang, Zhixiang Hu, Chengbin Tang, Qing Zhao, Qing Gong, Yongchang Ouyang
Publikováno v:
Chemico-biological interactions. 369
Programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) interaction exerts a vital role in tumor-associated immune evasion. While strategies disrupting PD-1/PD-L1 axis have shown clinical benefits in various cancers, the limited
Publikováno v:
Analytica Chimica Acta. 1209:339839
The global prevalence of diabetes makes it a significant work to develop flagship sensors in glucose monitoring technology. Particularly, exploring highly active nanocomposites as biomimetic catalysts for the enzymatic reaction of glucose is extremel
Publikováno v:
Current Microbiology. 63:68-74
Geldanamycin belongs to benzoquinone ansamycin antibiotic and has potent antitumor activities. In this study, a bacterial artificial chromosome (BAC) library with an average insert size of up to 150 kb was constructed from genomic DNA of Streptomyces
Autor:
Guanghua Wang, Yongchang Ouyang, Houbo Wu, Shikun Dai, Xiang Li, Keqian Yang, Lianwu Xie, Minjie Chen
Publikováno v:
Antonie van Leeuwenhoek. 99:807-815
Angucyclines are aromatic polyketides with antimicrobial, antitumor, antiviral and enzyme inhibition activities. In this study, a new pair of degenerate primers targeting the cyclase genes that are involved in the aromatization of the first and/or se
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 62:75-79
Herbimycin A, a typically water-insoluble anti-tumor drug and an analog of geldanamycin, was transformed by fungus Eupenicillium sp. SD017. The water solubility and anti-tumor activity of converted products were evaluated after separation, purificati
Exploring and Exploiting Microbial Diversity through Metagenomics for Natural Product Drug Discovery
Publikováno v:
Current Topics in Medicinal Chemistry. 9:1525-1535
Microorganisms of millions species exist in every corner of the Earth, and form a dynamic genetic reservoir that are not clearly revealed and categorized due to barrier in current cultivation technology. Their applications in biomedical and environme
Autor:
Danling Tang, Huimin Sun, Lianwu Xie, Yongchang Ouyang, M. S. Ravi Kumar, Shikun Dai, Wei Sun, Xiang Li
Publikováno v:
Marine Biotechnology. 12:318-325
Metagenomics is a powerful tool for mining the genetic repositories from environmental microorganisms. Bacteria associated with marine sponges (phylum Porifera) are rich sources of biologically active natural products. However, to date, few compounds
Autor:
Xiang Li, Yatao Guo, Danyan Zhou, Wen Chen, Yongchang Ouyang, Hengzhi Zhao, Shikun Dai, Houbo Wu, Guanghua Wang
Publikováno v:
African Journal of Microbiology Research. 6
A total of 110 culturable actinobacteria associated with seagrass (Thalassia hemprichii) were isolated using six different culture media, and their bioactivity potentials were analysed based on their genetic background on polyketide synthetase (PKS)