Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yongchan Lee"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis is a life-threatening inflammatory condition caused by dysregulated host responses to infection. Extracellular cold-inducible RNA-binding protein (eCIRP) is a recently discovered damage-associated molecular pattern that causes infl
Externí odkaz:
https://doaj.org/article/551535993eab4cc985aff034a9d2aa2b
Autor:
Yongchan Lee, Outi Haapanen, Anton Altmeyer, Werner Kühlbrandt, Vivek Sharma, Volker Zickermann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Many bacteria employ unique membrane transport systems to survive harsh environmental conditions. Here, authors determined the structure of a cation/proton antiporter at high resolution and studied its mechanism by computer simulations.
Externí odkaz:
https://doaj.org/article/88d63ce2ef994b119a7dfc4e00839e90
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-14 (2022)
Abstract Background Neutrophils are the most abundant innate immune cells in the circulating blood, and they act as the first responder against bacterial and fungal infection. However, accumulation of activated neutrophils can cause severe inflammati
Externí odkaz:
https://doaj.org/article/4d0193dc038e4348ab89ff544a812b2c
Autor:
Yongchan Lee, Pattama Wiriyasermkul, Pornparn Kongpracha, Satomi Moriyama, Deryck J. Mills, Werner Kühlbrandt, Shushi Nagamori
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Cystinuria is caused by mutations in heterodimeric amino acid transporter known as system b0,+. Here, authors discover that Ca2+ stabilizes the interface between two system b0,+ regulatory subunits rBAT, leading to super-dimerization of the b0,+AT–
Externí odkaz:
https://doaj.org/article/e598523dc76944279cc21426e1122f3e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern promoting inflammation and tissue injury. During bacterial or viral infection, macrophages release DNA decorated with nuclear and cytoplasmic proteins k
Externí odkaz:
https://doaj.org/article/00763670f66e4dbf807d4df71dc71d5c
Autor:
Kazumasa Oda, Takashi Nomura, Takanori Nakane, Keitaro Yamashita, Keiichi Inoue, Shota Ito, Johannes Vierock, Kunio Hirata, Andrés D Maturana, Kota Katayama, Tatsuya Ikuta, Itsuki Ishigami, Tamaki Izume, Rie Umeda, Ryuun Eguma, Satomi Oishi, Go Kasuya, Takafumi Kato, Tsukasa Kusakizako, Wataru Shihoya, Hiroto Shimada, Tomoyuki Takatsuji, Mizuki Takemoto, Reiya Taniguchi, Atsuhiro Tomita, Ryoki Nakamura, Masahiro Fukuda, Hirotake Miyauchi, Yongchan Lee, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Michihiro Sugahara, Tetsunari Kimura, Tatsuro Shimamura, Takaaki Fujiwara, Yasuaki Yamanaka, Shigeki Owada, Yasumasa Joti, Kensuke Tono, Ryuichiro Ishitani, Shigehiko Hayashi, Hideki Kandori, Peter Hegemann, So Iwata, Minoru Kubo, Tomohiro Nishizawa, Osamu Nureki
Publikováno v:
eLife, Vol 10 (2021)
Channelrhodopsins (ChRs) are microbial light-gated ion channels utilized in optogenetics to control neural activity with light . Light absorption causes retinal chromophore isomerization and subsequent protein conformational changes visualized as opt
Externí odkaz:
https://doaj.org/article/bceebbada3ce47869ff14a50376a93f1
Autor:
Yongchan Lee, Jens C. Hamann, Mark Pellegrino, Joanne Durgan, Marie-Charlotte Domart, Lucy M. Collinson, Cole M. Haynes, Oliver Florey, Michael Overholtzer
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3212-3220.e4 (2019)
Summary: Metazoan cell death mechanisms are diverse and include numerous non-apoptotic programs. One program called entosis involves the invasion of live cells into their neighbors and is known to occur in cancers. Here, we identify a developmental f
Externí odkaz:
https://doaj.org/article/471df9d5812b4a9bb524a4d4f4f846c0
Autor:
Sawako Goto, Akihisa Tsutsumi, Yongchan Lee, Michihiro Hosojima, Hideyuki Kabasawa, Koichi Komochi, Satoru Nagatoishi, Kazuya Takemoto, Kouhei Tsumoto, Tomohiro Nishizawa, Masahide Kikkawa, Akihiko Saito
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/28/2024, Vol. 121 Issue 22, p1-10, 30p
Autor:
Archna Sharma, Ezgi Sari, Yongchan Lee, Shivani Patel, Max Brenner, Philippe Marambaud, Ping Wang
Publikováno v:
Molecular Neurobiology. 60:3311-3328
Autor:
Chuyi Tan, Bridgette Reilly, Alok Jha, Atsushi Murao, Yongchan Lee, Max Brenner, Monowar Aziz, Ping Wang
Publikováno v:
J Immunol
Extracellular cold-inducible RNA binding protein (eCIRP) is an inflammatory mediator that causes inflammation and tissue injury in sepsis. Gasdermin D (GSDMD) is a protein that, when cleaved, forms pores in the cell membrane, releasing intracellular