Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Yongbo, Lu"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Family with sequence similarity 20, member A (FAM20A) is a pseudo-kinase in the secretory pathway and is essential for enamel formation in humans. Here we examine if FAM20A is a membrane-associated protein. We show that the full-length FAM20
Externí odkaz:
https://doaj.org/article/28e1358a449c4556ab0f17d8a89ead21
Autor:
Ruiya Yi, Bo Yang, Hongjie Zhu, Yu Sun, Hailan Wu, Zhihao Wang, Yongbo Lu, Ya-Wen He, Jing Tian
Publikováno v:
Nutrients, Vol 16, Iss 11, p 1562 (2024)
The imbalance of gut microbiota is an important factor leading to inflammatory bowel disease (IBD). Diffusible signal factor (DSF) is a novel quorum-sensing signal that regulates bacterial growth, metabolism, pathogenicity, and host immune response.
Externí odkaz:
https://doaj.org/article/56e2d75391b34813badde28df17ba8c3
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Upon endoplasmic reticulum (ER) stress, inositol-requiring enzyme 1 (IRE1) is activated, which subsequently converts an unspliced X-box binding protein 1 (XBP1U) mRNA to a spliced mRNA that encodes a potent XBP1S transcription factor. XBP1S is essent
Externí odkaz:
https://doaj.org/article/1eb9e54e55c342da9f76fc15e2aaa8b0
Autor:
Tian Liang, Charles E. Smith, Yuanyuan Hu, Hong Zhang, Chuhua Zhang, Qian Xu, Yongbo Lu, Ling Qi, Jan C.-C. Hu, James P. Simmer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Dentin sialophosphoprotein (DSPP) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells). Disease-causing DSPP mutations predominantly fall i
Externí odkaz:
https://doaj.org/article/55ab9e745bdb4551b1c1f56ebfdaf75c
Publikováno v:
Cancer Reports, Vol 6, Iss S1, Pp n/a-n/a (2023)
Abstract Background Breast cancer is a widespread disease in women worldwide. Aim We aimed to explore the global epidemiological trends of female breast cancer (FBC) between 1990 and 2044. Methods and Results Disease burden, population, and socio‐d
Externí odkaz:
https://doaj.org/article/d889634205944cb68b623a7553f7818a
Autor:
Tian Liang, Yuanyuan Hu, Hong Zhang, Qian Xu, Charles E. Smith, Chuhua Zhang, Jung-Wook Kim, Shih-Kai Wang, Thomas L. Saunders, Yongbo Lu, Jan C.-C. Hu, James P. Simmer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Non-syndromic inherited defects of tooth dentin are caused by two classes of dominant negative/gain-of-function mutations in dentin sialophosphoprotein (DSPP): 5′ mutations affecting an N-terminal targeting sequence and 3′ mutations that
Externí odkaz:
https://doaj.org/article/8cc6c2e7bcd84aac8371c3b57be3059c
Publikováno v:
Healthcare, Vol 10, Iss 9, p 1611 (2022)
Lip and oral cavity cancer is a common malignancy faced by many developing countries, and the disease burden is high in China. This study explored this cancer burden and its risk factors using data from China in the GBD 2019, along with predicting th
Externí odkaz:
https://doaj.org/article/a3777935f6cd43498a907b1340ef47dc
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7110 (2022)
Bacteria and their eukaryotic hosts have co-evolved for millions of years, and the former can intercept eukaryotic signaling systems for the successful colonization of the host. The diffusible signal factor (DSF) family represents a type of quorum-se
Externí odkaz:
https://doaj.org/article/673b1c0f9e2d45e1b50f2ab5c9f469d8
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract FAM20C mutations in humans cause Raine syndrome and our previous studies showed that global inactivation of mouse Fam20C led to bone and dental defects. By crossbreeding 2.3 kb Col 1a1-Cre mice with Fam20C flox/flox mice, we created 2.3 kb C
Externí odkaz:
https://doaj.org/article/c1d982c6916d4be18fc9de7cc858b32d
Autor:
Lora A. Shiflett, LeAnn M. Tiede-Lewis, Yixia Xie, Yongbo Lu, Eleanor C. Ray, Sarah L. Dallas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Bone formation, remodeling and repair are dynamic processes, involving cell migration, ECM assembly, osteocyte embedding, and bone resorption. Using live-cell imaging, we previously showed that osteoblast assembly of the ECM proteins fibronectin and
Externí odkaz:
https://doaj.org/article/e3593e815eee4f6291791fa2b2a0fafb