Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Yongan Wang"'
Autor:
Weijie Yang, Xiuxing Lei, Fengying Liu, Xin Sui, Yi Yang, Zhenyu Xiao, Ziqi cui, Yangyang Sun, Jun Yang, Xinyi Yang, Xueyang Lin, Zhenghao Bao, Weidong Li, Yingkai Ma, Yongan Wang, Yuan Luo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Stroke is a globally dangerous disease capable of causing irreversible neuronal damage with limited therapeutic options. Meldonium, an inhibitor of carnitine-dependent metabolism, is considered an anti-ischemic drug. However, the
Externí odkaz:
https://doaj.org/article/3696dff9a8ac4c46b00bdc53c0012fb9
Autor:
Fengying Liu, Huanhuan He, Weijie Yang, Daohui Wang, Xin Sui, Yangyang Sun, Shuai Wang, Yi Yang, Zhenyu Xiao, Jun Yang, Yongan Wang, Yuan Luo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Acute hypobaric hypoxia-induced brain injury has been a challenge in the health management of mountaineers; therefore, new neuroprotective agents are urgently required. Meldonium, a well-known cardioprotective drug, has been repor
Externí odkaz:
https://doaj.org/article/ffd69068ea294941bf9e15ad54a182ac
Autor:
Shuai Guo, Shun Yao, Huanchun Xing, Wenbin Cao, Jianyu Wang, Xinran Zhao, Yajing Wei, Ruizhi Lin, Xin Sui, Yuan Luo, Jun Deng, Jun Yang, Yongan Wang
Publikováno v:
Materials & Design, Vol 246, Iss , Pp 113286- (2024)
Sulfur mustard (2,2′-dichloroethylsulfide; SM) is a bifunctional alkylating agent that can easily penetrate skin and cause persistent pain and damage. Effective biological dressings are required to treat wounds caused or poisoned by SM. Though the
Externí odkaz:
https://doaj.org/article/61fbe6e1255b4b9898c512d15382297f
Autor:
Zinan Zhang, Wenbin Cao, Huanchun Xing, Shuai Guo, Lijuan Huang, Lin Wang, Xin Sui, Kui Lu, Yuan Luo, Yongan Wang, Jun Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1827-1844 (2024)
In the treatment of central nervous system disease, the blood–brain barrier (BBB) is a major obstruction to drug delivery that must be overcome. In this study, we propose a brain-targeted delivery strategy based on selective opening of the BBB. Thi
Externí odkaz:
https://doaj.org/article/468dba1313fe40e2a6c13b385fc8b961
Publikováno v:
Bioactive Materials, Vol 32, Iss , Pp 28-36 (2024)
Considerable efforts have been devoted to treating gastric ulcers. Attempts in this field tend to develop drug delivery systems with prolonged gastric retention time. Herein, we develop novel Chinese herb pollen-derived micromotors as active oral dru
Externí odkaz:
https://doaj.org/article/6654cfa6df5541b8ac94b02919245fbc
Publikováno v:
Drug Delivery, Vol 30, Iss 1, Pp 20-27 (2023)
AbstractOrganophosphorus agents, also known as nerve agents, are very dangerous chemicals that were used as chemical warfare agents. HI-6 is one of the most promising reactivators which is effective in reactivating AChE inhibited by many nerve agents
Externí odkaz:
https://doaj.org/article/1f2b4200001741968f0629a67340a807
Autor:
Xiaoning Wang, Xin Sui, Yangyang Sun, Ziqi Cui, Ning Ma, Shuai Wang, Jun Yang, Fengying Liu, Weijie Yang, Zhenyu Xiao, Tong Zhu, Yuan Luo, Yongan Wang
Publikováno v:
GeoHealth, Vol 8, Iss 4, Pp n/a-n/a (2024)
Abstract The Multi‐Threat Medical Countermeasure (MTMC) technique is crucial for developing common biochemical signaling pathways, molecular mediators, and cellular processes. This study revealed that the Nod‐like receptor 3 (NLRP3) inflammasome
Externí odkaz:
https://doaj.org/article/937cd9088e434fc2b0aca82d7155835e
Autor:
Lina Lin, Mengying Niu, Wei Gao, Chundong Wang, Qiaolin Wu, Fuquan Fang, Yongan Wang, Weijian Wang
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23299- (2024)
Background: Shedding of glycocalyx is relevant to worse prognosis in surgical patients, and elevated levels of serum matrix metalloproteinase-9 (MMP-9) are associated with this phenomenon. This study aimed to investigate the dynamic alterations of se
Externí odkaz:
https://doaj.org/article/d2ab230b392b42f799d3b0840c77cd51
Autor:
Lin Wang, Huanchun Xing, Shuai Guo, Wenbin Cao, Zinan Zhang, Lijuan Huang, Sui Xin, Yuan Luo, Yongan Wang, Jun Yang
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractMessenger RNA (mRNA) has become one of the most potential drugs in recent years. However, efficient and safe delivery of fragile and easily degradable mRNA is a major challenge. Appropriate delivery system (DS) determines the final effect of
Externí odkaz:
https://doaj.org/article/ee9e7a54592246869877ec9a439dfc9f
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 13, Iss 2, Pp 183-192 (2023)
Background and aim: Dachengqi Decoction (DCQD) as a classic traditional Chinese medicine has been reported to be effective in treating asthma, but its mechanism remains unknown. This study aimed to reveal the mechanisms of DCQD on the intestinal comp
Externí odkaz:
https://doaj.org/article/3a24ffc28b144980a2f2b28dcfa71f38