Zobrazeno 1 - 8
of 8
pro vyhledávání: '"YongTian Liang"'
Autor:
Julia Ring, Jelena Tadic, Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunović, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen, Cornelia Sommer, Mirjana Ninkovic, Sandra Seba, Patrick Rockenfeller, Friederike‐Nora Vögtle, Jörn Dengjel, Chris Meisinger, Adrian Keller, Stephan J Sigrist, Tobias Eisenberg, Frank Madeo
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-26 (2022)
Abstract Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer’s disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic approach using a yeast m
Externí odkaz:
https://doaj.org/article/4c65d2eea54842d29ae6240b593bf7ff
Autor:
YongTian Liang, Chengji Piao, Christine B. Beuschel, David Toppe, Laxmikanth Kollipara, Boris Bogdanow, Marta Maglione, Janine Lützkendorf, Jason Chun Kit See, Sheng Huang, Tim O.F. Conrad, Ulrich Kintscher, Frank Madeo, Fan Liu, Albert Sickmann, Stephan J. Sigrist
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108941- (2021)
Summary: Mitochondrial function declines during brain aging and is suspected to play a key role in age-induced cognitive decline and neurodegeneration. Supplementing levels of spermidine, a body-endogenous metabolite, has been shown to promote mitoch
Externí odkaz:
https://doaj.org/article/973855efe1694596aa789d1da04bdb4d
Autor:
YongTian Liang
Publikováno v:
Cells, Vol 8, Iss 1, p 34 (2019)
Protein homeostasis (proteostasis) is crucial to the maintenance of neuronal integrity and function. As the contact sites between neurons, synapses rely heavily on precisely regulated protein-protein interactions to support synaptic transmission and
Externí odkaz:
https://doaj.org/article/2635a969206c4e478215211173857520
Autor:
Wonyul Jang, Dmytro Puchkov, Paula Samsó, YongTian Liang, Michal Nadler-Holly, Stephan J. Sigrist, Ulrich Kintscher, Fan Liu, Kamel Mamchaoui, Vincent Mouly, Volker Haucke
Publikováno v:
Science. 378
Cells respond to fluctuating nutrient supply by adaptive changes in organelle dynamics and in metabolism. How such changes are orchestrated on a cell-wide scale is unknown. We show that endosomal signaling lipid turnover by MTM1, a phosphatidylinosit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b13276a2da10877b3e14a8639e2efe
https://doi.org/10.1126/science.abq5209
https://doi.org/10.1126/science.abq5209
Autor:
Sebastian J. Hofer, Sabrina Schroeder, YongTian Liang, Tobias Eisenberg, Jörn Dengjel, Frank Madeo, Andreas Zimmermann, Stephan J. Sigrist, Guido Kroemer
Publikováno v:
Autophagy
article-version (VoR) Version of Record
Autophagy, 2021, 17 (8), pp.2037-2039. ⟨10.1080/15548627.2021.1933299⟩
article-version (VoR) Version of Record
Autophagy, 2021, 17 (8), pp.2037-2039. ⟨10.1080/15548627.2021.1933299⟩
International audience; Spermidine is a natural polyamine, central to cellular homeostasis and growth, that promotes macroautophagy/autophagy. The polyamine pathway is highly conserved from bacteria to mammals and spermidine (prominently found in som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe8b6d33d6c5f29fd7c8d5ffbea5e45
https://pubmed.ncbi.nlm.nih.gov/34105442
https://pubmed.ncbi.nlm.nih.gov/34105442
Autor:
YongTian, Liang
Publikováno v:
Histology and histopathology. 36(10)
Complex neural and brain functions are executed through structural and functional alterations of synapses and neurons. Neuronal compartmentalization requires neurons to allocate mitochondria and proteins in a spatiotemporal manner to allow their plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c6390cc731d26e11504fa8e15ea0cc1
https://pubmed.ncbi.nlm.nih.gov/34032272
https://pubmed.ncbi.nlm.nih.gov/34032272
Autor:
Christine B. Beuschel, Fan Liu, Boris Bogdanow, Tim Conrad, Frank Madeo, Ulrich Kintscher, Stephan J. Sigrist, YongTian Liang, Marta Maglione, Janine Lützkendorf, Jason Chun Kit See, David Toppe, Sheng Huang, Albert Sickmann, Laxmikanth Kollipara, Chengji Piao
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108941-(2021)
Summary: Mitochondrial function declines during brain aging and is suspected to play a key role in age-induced cognitive decline and neurodegeneration. Supplementing levels of spermidine, a body-endogenous metabolite, has been shown to promote mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b89487961d5270ec964f941472ab78e
https://pubmed.ncbi.nlm.nih.gov/33852845
https://pubmed.ncbi.nlm.nih.gov/33852845
Autor:
YongTian Liang
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9783319981451
The imbalance of proteostasis has been implicated in brain aging and neurodegenerative diseases. Therefore, clearing dysfunctional proteins and organelles in neurons via macroautophagy opens a new avenue to rejuvenate the protein pools and, thus, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c669211d1d018cd85f69076dc18198fb
https://doi.org/10.1007/978-3-319-98146-8_9
https://doi.org/10.1007/978-3-319-98146-8_9
