Zobrazeno 1 - 10
of 27
pro vyhledávání: '"YongLong, Han"'
Autor:
Lanyi Wei, Jingjing Meng, Danfeng Xiang, Quanjun Yang, Yangyun Zhou, Lingyan Xu, Mengyue Wang, Junjun Chen, Yonglong Han
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract Objective The main objectives of this study were to identify the active components of Tongguanteng injection (TGT) and investigate the preclinical efficacy and mechanism of TGT on osteosarcoma using a combination of network pharmacology and
Externí odkaz:
https://doaj.org/article/f2ba9eeae54944ddb031351d80fca0da
Autor:
Quanjun Yang, Juan Hao, Mengyi Chi, Yaxian Wang, Bo Xin, Jinglu Huang, Jin Lu, Jie Li, Xipeng Sun, Chunyan Li, Yan Huo, Jianping Zhang, Yonglong Han, Cheng Guo
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Accumulated oncometabolites in the tumor microenvironment (TME) suppresses the metabolism, expansion, and function of T cells. Immunosuppressive TME also impeded Chimeric Antigen Receptor (CAR)-T cells mediated cytotoxicity since CAR-T cells had to a
Externí odkaz:
https://doaj.org/article/5793334be3c34154a2e2ba0c6e30a447
Publikováno v:
Annals of Hepatology, Vol 20, Iss , Pp 100259- (2021)
Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S. miltiorrhiza as well as S.
Externí odkaz:
https://doaj.org/article/32665a76363a41438730dc6c164424eb
Autor:
Nan Zhang, Nannan Shi, Siyu Li, Guoxiu Liu, Yonglong Han, Li Liu, Xin Zhang, Xiangwen Kong, Bihua Zhang, Wenpeng Yuan, Yi Liu, Deqiang Deng, Minxia Zheng, Ying Zhang, Lihua Li, Xiaoping Wang, Jiankun Wu, Xiaolan Lin, Hua Nian, Xiaohong Wu, Hua Wang, Fang Liu, Hongli Wang, Hongshun Wang, Ying Liu, Weixin Zeng, Manqin Yang, Yanping Wang, Huaqiang Zhai, Yongyan Wang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Objective: This research aims to analyze the application regularity of Chinese patent medicine during the COVID-19 epidemic by collecting the names of the top three Chinese patent medicines used by 24 hospitals in 14 provinces of China in four time p
Externí odkaz:
https://doaj.org/article/cf39d3aebb464c218baaab7723cd61a2
Autor:
Yangyun Zhou, Jingxian Feng, Qing Li, Doudou Huang, Xiao Chen, Zenan Du, Zongyou Lv, Ying Xiao, Yonglong Han, Junfeng Chen, Wansheng Chen
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Salvia miltiorrhiza Bunge (Lamiaceae) is an economically important medicinal plant as well as an emerging model plant. Our previous studies indicate that SmMYC2b is a positive transcription factor that can affect the biosynthesis of phenolic acids an
Externí odkaz:
https://doaj.org/article/4b4bcb71f2814044a64a6d5b27935c92
Autor:
Junjun Chen PhD, Xiangqi Zhang MS, Xiao Xiao MS, Yawei Ding MS, Wei Zhang MS, Meizhi Shi MS, Jiao Yang MS, Ying Liu MS, Yonglong Han PhD
Publikováno v:
Integrative Cancer Therapies, Vol 19 (2020)
Chemotherapy is an effective treatment for invasive breast cancer. Paradoxically, many recently published findings showed that the first-line chemotherapeutic agent paclitaxel (PTX) showed pro-metastatic effects in the progress of treating breast can
Externí odkaz:
https://doaj.org/article/d6145cda328a463fa44b3b0e6b048cab
Publikováno v:
Gastroenterology Research and Practice, Vol 2020 (2020)
Aims. Fibroblast growth factor receptor 4 (FGFR4) is a key mediator that protects the liver from chronic injury. MicroRNA-7 (miR-7) is a tumor suppressor and associated with lipid homeostasis in the liver. This study was designed to examine the role
Externí odkaz:
https://doaj.org/article/1475306465294abb81210fb169bf175e
Autor:
Jin Lu, Lili Wan, Yuan Zhong, Qi Yu, Yonglong Han, Pengguo Chen, Beiyun Wang, Wei Li, Ya Miao, Cheng Guo
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 188-195 (2015)
The therapeutic response rates of patients to donepezil vary from 20% to 60%, one of the reasons is their genetic differences in donepezil-metabolizing enzymes, which directly influence liver metabolism. However, the mechanism of donepezil metabolism
Externí odkaz:
https://doaj.org/article/f14b10a288104cc8a1d4bfae5c2aa3a4
Autor:
Xipeng Sun, Li Zhou, Yonglong Han, Quanjun Yang, Xingxia Li, Bo Xin, Mengyi Chi, Yaxian Wang, Cheng Guo
Publikováno v:
Chemistry & Biodiversity. 20
The anthracycline antibiotic doxorubicin (DOX) is an effective anticancer agent, but its clinical use is limited by dose-dependent cardiotoxicity. Scutellarin (SCU), a natural polyphenolic flavonoid, is used as a cardioprotective agent for infarction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2766ee49c2f07f918dbdf22e16f5b224
https://doi.org/10.1002/cbdv.202200450
https://doi.org/10.1002/cbdv.202200450
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 82
Studies on doxorubicin (DOX)-induced cardiotoxicity have mainly focused on cardiomyocytes (CMs), but it is unclear whether there are differences in the toxicity degree of DOX to CMs, cardiac fibroblasts (CFs) and endothelial cells (ECs). We used H9c2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5f82c4524a0a494a5347c6fba3a38b
https://pubmed.ncbi.nlm.nih.gov/35470029
https://pubmed.ncbi.nlm.nih.gov/35470029