Zobrazeno 1 - 10
of 221
pro vyhledávání: '"YongGuo Li"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-5 (2024)
Abstract Background The diagnosis and management of fever of unknown origin pose significant challenges in the field of infectious diseases, as it is influenced by various factors. Infectious diseases have long been recognized as the primary etiology
Externí odkaz:
https://doaj.org/article/c8ef67fc096c47b4a5174c925b5ca566
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a predominant liver disease worldwide, lacking approved drugs for clinical intervention at present. The composite dietary antioxidant index (CDAI) is used to ass
Externí odkaz:
https://doaj.org/article/f3158ec6126945d4aaf9fefb4a37b73f
Autor:
Hongrui Chen, Bin Sun, Wei Gao, Yajing Qiu, Wei Wei, Yongguo Li, Wei Ye, Haoliang Song, Chen Hua, Xiaoxi Lin
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110467- (2024)
Summary: Facial infiltrating lipomatosis (FIL) is a congenital disorder. The pathogenesis of FIL is associated with PIK3CA mutations, but the underlying mechanisms remain undetermined. We found that the adipose tissue in FIL demonstrated adipocytes h
Externí odkaz:
https://doaj.org/article/50a4bf4f9b874d99b792658cd78c73fd
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Epigenetic remodeling at effector gene loci has been reported to be critical in regulating T cell differentiation and function. However, efforts to investigate underlying epigenetic mechanisms that control T cell behaviors have be
Externí odkaz:
https://doaj.org/article/f0ae2805cce347a5a9762ff133689a25
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract There is a lack of scoring system to predict the occurrence of cirrhosis in individuals with acute-on-chronic liver failure (ACLF) in the absence of cirrhosis. The goal of this study was to develop a psoas muscle index (PMI)-based nomogram f
Externí odkaz:
https://doaj.org/article/e44ecebfc2eb482bbb3bc3780e597431
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012113 (2024)
Chronic viral infections cause T cell dysfunction in both animal models and human clinical settings, thereby affecting the ability of the host immune system to clear viral pathogens and develop proper virus-specific immune memory. However, the impact
Externí odkaz:
https://doaj.org/article/ca45db4e31f7410ba8a2b507c2046cd2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Background:The mechanical properties of the aorta are particularly important in clinical medicine and forensic science, serving as basic data for further exploration of aortic disease or injury mechanisms.Objective:To study the influence of various f
Externí odkaz:
https://doaj.org/article/77f9d786777a4fbc96e49f36fad16e74
Autor:
Chengyin Yu, Hongjie Qian, Qingqing Wu, Yang Zou, Qicheng Ding, Yuting Cai, Liyu Liang, Juncai Xu, Lei Li, Bin Zan, Yongguo Li, Yun Liu
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract This study aimed to assess the safety, pharmacokinetics, and food impact on sudapyridine (WX‐081), a novel drug designed to inhibit mycobacterium ATP synthase, with clinical applications for drug‐resistant tuberculosis (TB) treatment. Th
Externí odkaz:
https://doaj.org/article/3ef73d703b9444ae8e3596ff07624e4a
Autor:
Hongli Xiong, Zhe Zheng, Congcong Zhao, Minzhu Zhao, Qi Wang, Peng Zhang, Yongguo Li, Ying Zhu, Shisheng Zhu, Jianbo Li
Publikováno v:
Proteome Science, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background DCM is a common cardiomyopathy worldwide, which is characterized by ventricular dilatation and systolic dysfunction. DCM is one of the most widespread diseases contributing to sudden death and heart failure. However, our understan
Externí odkaz:
https://doaj.org/article/8762914b76fe4c2f89234c3d8f5833fc
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionHepatocellular carcinoma (HCC) is the most common type of cancer worldwide and is a major public health problem in the 21st century. Disulfidopathy, a novel cystine-associated programmed cell death, plays complex roles in various tumors.
Externí odkaz:
https://doaj.org/article/4540a3d2a8854b2791e3ab0829035d41