Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yong-kui Jing"'
Publikováno v:
Molecules, Vol 14, Iss 10, Pp 4166-4179 (2009)
A series of novel 2-phenylaminopyrimidine (PAP) derivatives structurally related to STI-571 were designed and synthesized. The abilities of these compounds to inhibit proliferation were tested in human chronic myeloid leukemia K562 cells. (E)-3-(2-br
Externí odkaz:
https://doaj.org/article/61932666a7954473b901348f985eb047
Publikováno v:
Molecules, Vol 13, Iss 7, Pp 1487-1500 (2008)
Twenty-six 5-azacytidine analogues have been synthesized, including 4-amino- 6-alkyl-1-pyranosyl/ribofuranosyl-1,3,5-triazin-2(1H)-ones 1a-j, 6-amino-4-alkyl/aryl-1- pyranosyl/ribofuranosyl-1,3,5-triazin-2(1H)-ones 2a-f and 4-amino-6-alkyl-1,3,5-tria
Externí odkaz:
https://doaj.org/article/a3ce0f5beb494df89193278217355892
Publikováno v:
Molecules, Vol 13, Iss 6, Pp 1427-1440 (2008)
A series of novel substituted 1,2,3-benzotriazines based on the structures of vatalanib succinate (PTK787) and vandetanib (ZD6474) were designed and synthesized. The antiproliferative effects of these compounds were tested on microvascular endothelia
Externí odkaz:
https://doaj.org/article/49b421babb4e438db0ae59b0369774bd
Autor:
Sheng-Ge Li, Xu Hu, Qin Zhang, Yan-Hui Zan, Kai-Bo Wang, Chun-Yu Jiang, Jing-Jing Xue, Yong-Xiang Liu, Bin Lin, Yong-Kui Jing, Da-Hong Li, Hui-Ming Hua
Publikováno v:
Organic & Biomolecular Chemistry. 20:8528-8532
Two pairs of unprecedented β-carboline-phenylpropanoid alkaloids, (±)-pheharmines A–B (1–4), characterized by a morpholino[4,3,2-hi]β-carboline core with two chiral centers, were isolated from the roots of Peganum harmala.
Autor:
Chun-Xue Zhao, Hui Liu, Xin Zhang, Meng-Yue Yang, Yue-Tong Wang, Yi-Jia Xing, Jun-Xin Hua, Qin Zhang, Da-Hong Li, Jiao Bai, Yong-Kui Jing, Hui-Ming Hua
Publikováno v:
Organic & Biomolecular Chemistry. 20:7076-7084
1 is the first nitrogen-oxidized homoerythrina-type alkaloid isolated from Cephalotaxus genus. 31 exhibited a significant antitumor effect in THP-1 and K562 cancer cell lines with GI50 values of 0.24 and 0.29 μM.
Autor:
Meng-Yue Yang, Zhao-Xiang Shao, Yue-Tong Wang, Yong-Lian Hou, Ding-Kang Zhu, Sha Chen, Ya-Hui Zhang, Fei Cao, Yong-Kui Jing, Bin Lin, Zhan-Lin Li, Da-Hong Li, Hui-Ming Hua
Publikováno v:
Phytochemistry. 205
Stilbenes (based on the 1,2-diphenylethylene skeleton) are a class of plant polyphenols with rich structural and bioactive diversity. Twenty-six stilbenes, including five undescribed compounds (7,8-dioxy-4,3',5'-trihydroxystilbene, trans-13'-methoxyg
Autor:
Hui-Ming Hua, Jingjing Xue, Yong-Kui Jing, Yue-Tong Wang, Qin Zhang, Dahong Li, Bin Lin, Kai-Bo Wang, Sheng-Ge Li
Publikováno v:
Organic Letters. 22:7522-7525
Two nonbiaryl axially chiral β-carboline-quinazoline dimers, pegaharmols A (1) and B (2), were isolated from the roots of Peganum harmala. Their planar structures were elucidated by the spectroscopic methods of high-resolution mass spectrometry and
Autor:
Sheng-Ge, Li, Yue-Tong, Wang, Qin, Zhang, Kai-Bo, Wang, Jing-Jing, Xue, Da-Hong, Li, Yong-Kui, Jing, Bin, Lin, Hui-Ming, Hua
Publikováno v:
Organic letters. 22(19)
Two nonbiaryl axially chiral β-carboline-quinazoline dimers, pegaharmols A (
Autor:
Yan-Zhi Li, Chun-Yu Jiang, Yue-Tong Wang, Jiu-Zhi Yuan, Bin Lin, Bing-Qian Li, Yong-Kui Jing, Hui-Ming Hua, Dahong Li, Chun-Xue Zhao, Qinxue Jing
Publikováno v:
Fitoterapia. 155:105037
Eight cephalotaxine-type alkaloids (1–8), including two new compounds cephafortunines A and B (1–2), were isolated from the branches and leaves of Cephalotaxus fortunei var. alpina. Their structures were identified by a series of spectroscopic me
Autor:
Chun-Mei Xue, Jin-Cai Lu, Chun-Mei Sai, Hui-Ming Hua, Tong Han, Yong-Kui Jing, Zhan-Lin Li, Jian-Yong Li, Dahong Li, Kai-Bo Wang
Publikováno v:
Journal of Natural Products. 80:2893-2904
Inspired by the intriguing structures and bioactivities of dimeric alkaloids, 11 new thalifaberine-type aporphine-benzylisoquinoline alkaloids, thalicultratines A-K, a tetrahydroprotoberberine-aporphine alkaloid, thalicultratine L, and five known one