Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Yong-Zhou Hu"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction. By controlling the use of bases, both 6-aza-chromones 5 and 3-(4-oxo-1,4-
Externí odkaz:
https://doaj.org/article/e2290e184752452ab45873be86b563b7
Autor:
Xiao-Chun Yang, Shi-Jing Qian, Li Wang, Si-Da Liao, Ji Cao, Yong-Zhou Hu, Qiao-Jun He, Hong Zhu, Bo Yang
Publikováno v:
Translational Oncology, Vol 6, Iss 1, Pp 75-82 (2013)
A novel VP-16 derivative, 4β-[N -(4‴-acetyloxyl-phenyl-1‴-carbonyl)-4″-aminoanilino]-4′-O-demethyl-4-desoxypodophyllotoxin (GL3), displayed a wide range of cytotoxicity in a panel of human tumor cell lines, with half-maximal inhibitory conce
Externí odkaz:
https://doaj.org/article/a8e7dbe1fef94dbc9bdb59c0dda0d158
Autor:
Bo Yang, Qiao-jun He, Neng-ming Lin, Yong-zhou Hu, Xiao-wu Dong, Hai Jiang, Liu-qing Yang, Hong Zhu, Tian-yu Cai, Chong Zhang
The Bcl-2 antagonist ABT-737 targets Bcl-2/Bcl-xL, but not Mcl-1, which may confer resistance to this agent in various cancers with high levels of Mcl-1. Here, we showed that the combination of gemcitabine and ABT-737 exhibited synergistic cytotoxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc21bba522acfd16e1d4d2120bb3ad8b
https://doi.org/10.1158/1535-7163.c.6535453
https://doi.org/10.1158/1535-7163.c.6535453
Autor:
Bo Yang, Qiao-jun He, Neng-ming Lin, Yong-zhou Hu, Xiao-wu Dong, Hai Jiang, Liu-qing Yang, Hong Zhu, Tian-yu Cai, Chong Zhang
Supplementary Methods, Figures 1-3 from Synergistic Antitumor Activity of Gemcitabine and ABT-737 In Vitro and In Vivo through Disrupting the Interaction of USP9X and Mcl-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d023ea7789211516a9ca9c7faf3744
https://doi.org/10.1158/1535-7163.22496977.v1
https://doi.org/10.1158/1535-7163.22496977.v1
Autor:
Eric M. Miller, Qing Xia, Mariah E. Cella, Austin W. Nenninger, Monica N. Mruzik, Krystina A. Brillos-Monia, Yong Zhou Hu, Rong Sheng, Christina M. Ragain, Philip W. Crawford
Publikováno v:
Molecules, Vol 22, Iss 9, p 1442 (2017)
The electrochemical properties of twenty 3-aryl-quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives with varying degrees of cytotoxic activity were investigated in dimethylformamide (DMF) using cyclic voltammetry and first derivative cyclic voltamm
Externí odkaz:
https://doaj.org/article/bf75389007d14db8b153b79d64e377be
Autor:
Yong Zhou Hu, Quan Jiang, Cheng Kun Wang, Chao Tan, Ying Mei Lu, Xin Li, Xing Guang Liang, Kohji Fukunaga, Juan Cheng, Feng Han
Publikováno v:
Theranostics
Overproduction of H2O2 causes oxidative stress and is the hallmark of vascular diseases. Tracking native H2O2 in the endothelium is therefore indispensable to gain fundamental insights into this pathogenesis. Previous fluorescent probes for H2O2 imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f546858a277b39276955e54c33357ddb
https://doi.org/10.7150/thno.21068
https://doi.org/10.7150/thno.21068
Publikováno v:
RSC advances. 8(20)
CXCR1 and CXCR2 are CXC chemokine receptors (CXCRs), corresponding to cytokines of the CXC chemokine family. CXCR2 was found to be 77% homologous to CXCR1. Antagonism of the chemokine receptor CXCR2 has been proposed as a new strategy for the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ba360de2ed4e00350766e3cffe7a83c
https://pubmed.ncbi.nlm.nih.gov/35541503
https://pubmed.ncbi.nlm.nih.gov/35541503
Autor:
Qing Xia, Christina M. Ragain, Austin W. Nenninger, Krystina A. Brillos-Monia, Mariah E. Cella, Rong Sheng, Monica N. Mruzik, Philip W. Crawford, Yong Zhou Hu, Eric M. Miller
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 9, p 1442 (2017)
Molecules; Volume 22; Issue 9; Pages: 1442
Molecules, Vol 22, Iss 9, p 1442 (2017)
Molecules; Volume 22; Issue 9; Pages: 1442
The electrochemical properties of twenty 3-aryl-quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives with varying degrees of cytotoxic activity were investigated in dimethylformamide (DMF) using cyclic voltammetry and first derivative cyclic voltamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851375dc862949938804b00195fbd749
https://pubmed.ncbi.nlm.nih.gov/28858261
https://pubmed.ncbi.nlm.nih.gov/28858261
Publikováno v:
Autophagy
Tumor hypoxia underlies treatment failure and yields more aggressive and metastatic cancer phenotypes. Although therapeutically targeting these hypoxic environments has been proposed for many years, to date no approaches have shown the therapeutic va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018b17af9d60c0582d9c49748d64c3b1
Autor:
Yong‐Zhou Hu, Wen‐Jie Tang
Publikováno v:
Synthetic Communications. 36:2461-2468
A general and efficient method for the preparation of 2,4‐diaryl‐1,2,3‐triazoles from α‐hydroxyacetophenones and phenylhydrazines is reported. The essential characteristics of this method include mild reaction conditions, a straightforward w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4d31501834969910676e3e7e6f626a
https://doi.org/10.1080/00397910600781216
https://doi.org/10.1080/00397910600781216