Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yong-Tao Duan"'
Publikováno v:
Chemical Society Reviews. 51:7752-7778
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of cell death is involved in the development and progression of several di
Autor:
Ya-Lin Qi, Yun-Zhan Li, Ming-Jun Tan, Fang-Fang Yuan, Niren Murthy, Yong-Tao Duan, Hai-Liang Zhu, Sheng-Yu Yang
Publikováno v:
Coordination Chemistry Reviews. 486:215130
Publikováno v:
Biomaterials Science. 9:6501-6509
Recently, hypothermal photothermal therapy (HPTT) seemed essential for the future clinical transformation of cancer optical therapies. However, at a lower working temperature, heat shock proteins (HSPs) seriously affect the anti-tumor effect of HPTT.
Publikováno v:
Journal of Molecular Liquids. 370:121012
Autor:
Song‐Yu Wu, Ya‐Xi Ye, Qing Zhang, Qian‐Jin Kang, Zhu‐Min Xu, Shen‐Zhen Ren, Fan Lin, Yong‐Tao Duan, Hao‐Jun Xu, Zi‐Yi Hu, Sui‐Sui Yang, Hai‐Liang Zhu, Mei‐Juan Zou, Zhong‐Chang Wang
Publikováno v:
Advanced Science. 10:2203742
Photodynamic therapy (PDT) under hypoxic conditions and drug resistance in chemotherapy are perplexing problems in anti-tumor treatment. In addition, central nervous system neoplasm-targeted nanoplatforms are urgently required. To address these issue
Autor:
Yongfang Yao, Akshay Vyas, Rohit R. Koshti, Chetan B. Sangani, Yong-Tao Duan, Pranav S. Shrivastav, A.K. Prajapati, Rohit L. Vekariya, H.N. Patel
Publikováno v:
Journal of Molecular Liquids. 363:119893
Autor:
Yong-Tao Duan, Peng-Wen Chen, Muhammad Abbas, Hai-Liang Zhu, Peng-Cheng Lv, Qi-Xing Liu, Zhong-Chang Wang, Shen-Zhen Ren, Yi Liu, Wu Songyu, Xin Li, Li Zhang
Publikováno v:
European Journal of Medicinal Chemistry. 169:168-184
In this paper, 41 hybrid compounds containing diaryl-1,5-diazole and morpholine structures acting as dual COX-2/5-LOX inhibitors have been designed, synthesized and biologically evaluated. Most of them showed potent antiproliferative activities and C
Autor:
Yun-Jie Xu, Jian-Fei Xu, Xiao-Ming Wang, Qing Yuan, Tian-Tian Wang, Yu-Shun Yang, Hai-Liang Zhu, Yong-Tao Duan, Peng-Cheng Lv
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1509-1516
A series of rhodanine derivatives RB1–RB23 were synthesized through a two-round screening. Their Mycobacterial tuberculosis (Mtb) InhA inhibitory activity and Mtb growth blocking capability were evaluated. The most potent hit compound RB23 indicate
Publikováno v:
Current Topics in Medicinal Chemistry. 18:2395-2419
Epigenetics is defined as the stable and heritable alternations in gene expression without changing the DNA nucleotide sequence. The initiation and progression of cancer result from not only genetic mutation, but also aberrant epigenetic regulation,
Autor:
Yongfang Yao, Hong-Min Liu, Meng-Yu Ba, Moran Sun, Yong-Tao Duan, De-Quan Yu, Yixin Zhang, Jinling Qin
Publikováno v:
Bioorganic chemistry. 113
Here, we report the structural optimization of a hit natural compound, 2-ME2 (2-methoxyestradiol), which exhibited inhibitory activity but low potency on tubulin polymerization, anti- angiogenesis, MCF-7 proliferation and metastasis in vitro and in v