Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Yong-Sok Lee"'
Autor:
Pranav Kumar, Tadakimi Tomita, Thomas A. Gerken, Collin J. Ballard, Yong Sok Lee, Louis M. Weiss, Nadine L. Samara
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Infection with the apicomplexan protozoan Toxoplasma gondii can be life-threatening in immunocompromised hosts. Transmission frequently occurs through the oral ingestion of T. gondii bradyzoite cysts, which transition to tachyzoites, dissemi
Externí odkaz:
https://doaj.org/article/38f632452ed54bc1842575fe1d9de860
Publikováno v:
Eur J Inorg Chem
DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid)-based chelates that give only a single isomer in solution when complexed with lanthanide (Ln(3+)) ions is of value for studying protein dynamics and interactions via NMR. Herein, we have
Autor:
Malliga R. Iyer, Resat Cinar, Casey M. Wood, Charles N. Zawatsky, Nathan J. Coffey, Kyu Ah Kim, Ziyi Liu, Alexis Katz, Jasmina Abdalla, Sergio A. Hassan, Yong-Sok Lee
Publikováno v:
Journal of Medicinal Chemistry. 65:2374-2387
Autor:
Meining Wang, Thomas C. Irvin, Christine A. Herdman, Ramsey D. Hanna, Sergio A. Hassan, Yong-Sok Lee, Sophia Kaska, Rachel Saylor Crowley, Thomas E. Prisinzano, Sarah L. Withey, Carol A. Paronis, Jack Bergman, Saadet Inan, Ellen B. Geller, Martin W. Adler, Theresa A. Kopajtic, Jonathan L. Katz, Aaron M. Chadderdon, John R. Traynor, Arthur E. Jacobson, Kenner C. Rice
Publikováno v:
Molecules, Vol 25, Iss 11, p 2640 (2020)
(−)-N-Phenethyl analogs of optically pure N-norhydromorphone were synthesized and pharmacologically evaluated in several in vitro assays (opioid receptor binding, stimulation of [35S]GTPγS binding, forskolin-induced cAMP accumulation assay, and MO
Externí odkaz:
https://doaj.org/article/413521e5240a47c49d66570b815acccf
Autor:
Yong Sok Lee, Nathan J. Coffey, George Kunos, Jie Liu, Sergio A. Hassan, Ziyi Liu, Robert B. Innis, Charles N. Zawatsky, Tony Jourdan, Grzegorz Godlewski, Malliga R. Iyer, Resat Cinar, Jeih-San Liow, Jaroslawna Meister, Jürgen Wess, Henry L. Puhl
Publikováno v:
ACS Pharmacology & Translational Science. 4:1175-1187
Seven-transmembrane receptors signal via G-protein- and β-arrestin-dependent pathways. We describe a peripheral CB1R antagonist (MRI-1891) highly biased toward inhibiting CB1R-induced β-arrestin-2 ...
Publikováno v:
European Journal of Inorganic Chemistry. 2021:1428-1440
Autor:
Madeleine Strickland, Nico Tjandra, Rolf E. Swenson, Ana Christina L. Opina, Olga Vasalatiy, Yong Sok Lee
Publikováno v:
Inorg Chem
Polymethylated lanthanide 4S4R-M4DOTMA complexes bearing the ring methyl groups oriented in the SSSS position and the arm methyl groups in the RRRR configuration, exists exclusively as the SAP [Λ(δδδδ)] isomer in solution throughout the lanthani
Autor:
Michael P. Frankland, Jeih-San Liow, Christer Halldin, Anton Lindberg, Yong Sok Lee, Magnus Schou, Cheryl L. Morse, Shuiyu Lu, Nahid Amini, Charles S. Elmore, Robert B. Innis, Victor W. Pike, Sami S. Zoghbi, Akihiro Takano, Sangram Nag, Robert L. Gladding
Publikováno v:
Nuclear Medicine and Biology. 70:1-13
INTRODUCTION: The serotonin 1B receptor subtype is of interest in the pathophysiology and treatment of depression, anxiety, and migraine. Over recent years 5-HT(1B) receptor binding in human brain has been examined with PET using radio ligands that a
Autor:
Ziyi, Liu, Malliga R, Iyer, Grzegorz, Godlewski, Tony, Jourdan, Jie, Liu, Nathan J, Coffey, Charles N, Zawatsky, Henry L, Puhl, Jürgen, Wess, Jaroslawna, Meister, Jeih-San, Liow, Robert B, Innis, Sergio A, Hassan, Yong Sok, Lee, George, Kunos, Resat, Cinar
Publikováno v:
ACS pharmacologytranslational science. 4(3)
Seven-transmembrane receptors signal via G-protein- and β-arrestin-dependent pathways. We describe a peripheral CB
Autor:
François, Guérard, Yong-Sok, Lee, Raphaël, Tripier, Lawrence P, Szajek, Jeffrey R, Deschamps, Martin W, Brechbiel
Publikováno v:
Chemical communications (Cambridge, England). 56(83)
The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr