Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yong-Mo, Ahn"'
Autor:
R. M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sam
Externí odkaz:
https://doaj.org/article/78179b9a20084b6790bf89a43f40ffbf
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101971- (2023)
Summary: The extent to which a drug accumulates in Mycobacterium tuberculosis (Mtb) and its host cell can affect treatment efficacy. We describe protocols measuring drug accumulation in Mtb, macrophages, and Mtb-infected macrophages. The method lever
Externí odkaz:
https://doaj.org/article/0c7e55d9c5a2436c8042cb9121bdddcb
Autor:
Richard C Lavin, Calvin Johnson, Yong-Mo Ahn, Kyle M Kremiller, Matthew Sherwood, Jimmy S Patel, Yan Pan, Riccardo Russo, Nathan J MacGilvary, David Giacalone, Yuzo L Kevorkian, Matthew D Zimmerman, J Fraser Glickman, Joel S Freundlich, Shumin Tan
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001355 (2021)
Sensing and response to environmental cues, such as pH and chloride (Cl-), is critical in enabling Mycobacterium tuberculosis (Mtb) colonization of its host. Utilizing a fluorescent reporter Mtb strain in a chemical screen, we have identified compoun
Externí odkaz:
https://doaj.org/article/e8e92b4c6c2a4557821d17bd95672572
Autor:
R.M. Naseer Khan, Yong-Mo Ahn, Gwendolyn A. Marriner, Laura E. Via, Francois D’Hooge, Seung Seo Lee, Nan Yang, Falguni Basuli, Alexander G. White, Jaime A. Tomko, L. James Frye, Charles A. Scanga, Danielle M. Weiner, Michelle L. Sutphen, Daniel M. Schimel, Emmanuel Dayao, Michaela K. Piazza, Felipe Gomez, William Dieckmann, Peter Herscovitch, N. Scott Mason, Rolf Swenson, Dale O. Kiesewetter, Keriann M. Backus, Yiqun Geng, Ritu Raj, Daniel C. Anthony, JoAnne L. Flynn, Clifton E. Barry, Benjamin G. Davis
Tuberculosis remains a large global disease burden for which treatment regimens are protracted and monitoring of disease activity difficult. Existing detection methods rely almost exclusively on bacterial culture from sputum which limits sampling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a42fa0baad62a328a1b992d88f506f
https://doi.org/10.1101/2023.04.03.535218
https://doi.org/10.1101/2023.04.03.535218
Autor:
Tian Lan, Uday S. Ganapathy, Sachin Sharma, Yong‐Mo Ahn, Matthew Zimmerman, Vadim Molodtsov, Pooja Hegde, Martin Gengenbacher, Richard H. Ebright, Véronique Dartois, Joel S. Freundlich, Thomas Dick, Courtney C. Aldrich
Publikováno v:
Angewandte Chemie International Edition. 61
Rifamycin antibiotics are a valuable class of antimicrobials for treating infections by mycobacteria and other persistent bacteria owing to their potent bactericidal activity against replicating and non-replicating pathogens. However, the clinical ut
Autor:
Steven Park, Riccardo Russo, Landon Westfall, Riju Shrestha, Matthew Zimmerman, Veronique Dartois, Natalia Kurepina, Barry Kreiswirth, Eric Singleton, Shao-Gang Li, Nisha Mittal, Yong-Mo Ahn, Joseph Bilotta, Kristie L. Connolly, Ann E. Jerse, Joel S. Freundlich, David S. Perlin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 66
Drug-resistant Neisseria gonorrhoeae is a serious global health concern. New drugs are needed that can overcome existing drug resistance and limit the development of new resistances.
Autor:
Alexander Lemenze, Nisha Mittal, Alexander L. Perryman, Samer S. Daher, Sean Ekins, James Occi, Yong-Mo Ahn, Xin Wang, Riccardo Russo, Jimmy S. Patel, Robin M. Daugherty, David O. Wood, Nancy Connell, Joel S. Freundlich
Publikováno v:
ACS Infect Dis
Rickettsia is a genus of Gram-negative bacteria that has for centuries caused large-scale morbidity and mortality. In recent years, the resurgence of rickettsial diseases as a major cause of pyrexias of unknown origin, bioterrorism concerns, vector m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de72eb51dc86b1a2b07680accd692ec0
https://europepmc.org/articles/PMC9912140/
https://europepmc.org/articles/PMC9912140/
Autor:
Melissa D. Chengalroyen, Mandy K. Mason, Alessandro Borsellini, Raffaella Tassoni, Garth L. Abrahams, Sasha Lynch, Yong-Mo Ahn, Jon Ambler, Katherine Young, Brendan M. Crowley, David B. Olsen, Digby F. Warner, Clifton E. Barry III, Helena I. M. Boshoff, Meindert H. Lamers, Valerie Mizrahi
Publikováno v:
ACS Infectious Diseases, 8(3), 612-625. AMER CHEMICAL SOC
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fb2ed0c508f40ee8c1ebeb5a93f63a
https://hdl.handle.net/1887/3514350
https://hdl.handle.net/1887/3514350
Autor:
Melissa D, Chengalroyen, Mandy K, Mason, Alessandro, Borsellini, Raffaella, Tassoni, Garth L, Abrahams, Sasha, Lynch, Yong-Mo, Ahn, Jon, Ambler, Katherine, Young, Brendan M, Crowley, David B, Olsen, Digby F, Warner, Clifton E, Barry Iii, Helena I M, Boshoff, Meindert H, Lamers, Valerie, Mizrahi
Publikováno v:
ACS infectious diseases. 8(3)
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Autor:
Digby F. Warner, Melissa D. Chengalroyen, Sasha L. Lynch, Katherine Young, Mandy K. Mason, Brendan M. Crowley, Raffaella Tassoni, Valerie Mizrahi, David B. Olsen, Clifton E. Barry, Alessandro Borsellini, Garth L. Abrahams, Yong-Mo Ahn, Jon Ambler, Helena I. Boshoff, Meindert H Lamers
SUMMARYNatural products provide a rich source of potential antimicrobials for use in treating infectious diseases for which drug resistance has emerged. Foremost among these is tuberculosis. Assessment of the antimycobacterial activity of nargenicin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2413ae812a6154daa5b1ef262f9a95ec
https://doi.org/10.1101/2021.10.27.466036
https://doi.org/10.1101/2021.10.27.466036