Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yong-Long Zhao"'
Autor:
Yu-Chan Wang, Wen-Li Zhang, Rong-Hong Zhang, Chun-Hua Liu, Yong-Long Zhao, Guo-Yi Yan, Shang-Gao Liao, Yong-Jun Li, Meng Zhou
Publikováno v:
Molecules, Vol 28, Iss 24, p 8020 (2023)
As an important antiviral target, HIV-1 integrase plays a key role in the viral life cycle, and five integrase strand transfer inhibitors (INSTIs) have been approved for the treatment of HIV-1 infections so far. However, similar to other clinically u
Externí odkaz:
https://doaj.org/article/a18ade77fd9b4a40a49cb3dcbfef6aa6
Autor:
Yu-Chan Wang, Rong-Hong Zhang, Sheng-Cao Hu, Hong Zhang, Dan Yang, Wen-Li Zhang, Yong-Long Zhao, Dong-Bing Cui, Yong-Jun Li, Wei-Dong Pan, Shang-Gao Liao, Meng Zhou
Publikováno v:
Molecules, Vol 27, Iss 13, p 4040 (2022)
As a typical dibenzylisoquinoline alkaloid, tetrandrine (TET) is clinically used for the treatment of silicosis, inflammatory pulmonary, and cardiovascular diseases in China. Recent investigations have demonstrated the outstanding anticancer activity
Externí odkaz:
https://doaj.org/article/5cbc304a38dc42d48c5927a384947217
Autor:
Rong-Hong Zhang, Guo-Qi Chen, Weilin Wang, Yu-Chan Wang, Wen-Li Zhang, Ting Chen, Qian-Qian Xiong, Yong-Long Zhao, Shang-Gao Liao, Yong-Jun Li, Guo-Yi Yan, Meng Zhou
Publikováno v:
RSC Advances; 2024, Vol. 14 Issue 13, p9020-9031, 12p
Publikováno v:
RSC Advances. 13:12982-12990
A rapid and simple method was developed for the synthesis of diarylmethyl thioethers via a DABCO-catalyzed 1,6-conjugate addition reaction of para-quinone methides (p-QMs) with organosulfur reagents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6c6469b3adebe0ff4e165cc7bd430b
https://doi.org/10.1039/d3ra01815f
https://doi.org/10.1039/d3ra01815f
Autor:
Yong‐Long Zhao, Jian‐Xiong An, Fen‐Fen Yang, Xiang Guan, Xiao‐Zhong Fu, Zong‐Qin Li, Da‐Peng Wang, Meng Zhou, Yuan‐Yong Yang, Bin He
Publikováno v:
Advanced Synthesis & Catalysis. 364:1277-1285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044d1dd7cd8179b16fc077886a66fca1
https://doi.org/10.1002/adsc.202101498
https://doi.org/10.1002/adsc.202101498
Autor:
Fen-Fen Yang, Ming-Shan Shuai, Xiang Guan, Mao Zhang, Qing-Qing Zhang, Xiao-Zhong Fu, Zong-Qin Li, Da-Peng Wang, Meng Zhou, Yuan-Yong Yang, Ting Liu, Bin He, Yong-Long Zhao
Publikováno v:
RSC Advances. 12:25068-25080
In this work, based on the unique scaffold of indirubin, we synthesized 29 indirubin-3′-monoximes and preliminarily evaluated their antibacterial activities, especially against S. aureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3332ebef75943f0a7baca6338d072e91
https://doi.org/10.1039/d2ra01035f
https://doi.org/10.1039/d2ra01035f
Autor:
Jian-Xiong An, Fen-Fen Yang, Pan Wang, Zhi-Cheng Gu, Yan Li, Lei Chen, Yong-Long Zhao, Bin He
Publikováno v:
RSC Advances. 12:7040-7045
A simple and novel solid-supported organocatalyst from a 2-chlorotrityl chloride resin-immobilized 4-hydroxyproline was developed, which has been used for the asymmetric Mannich reaction of 2-aryl-3H-indol-3-ones and aldehydes/ketones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160dc2888ebc640df98f74644d857e05
https://doi.org/10.1039/d2ra00456a
https://doi.org/10.1039/d2ra00456a
Autor:
Di Chen, Zhuoxian Cao, Yong-Long Zhao, Jie Wang, Yi Wang, Yan Li, Hening Lin, Shuxian Lin, Zhicheng Gu, Bin He, Yongjun Li, Ting Liu
Publikováno v:
ACS Chemical Biology. 16:2746-2751
Histone deacetylase 6 (HDAC6) is a potential therapeutic target for treating several diseases. A recent study revealed that HDAC6 is important for NLRP3 inflammasome activation, suggesting that targeting HDAC6 could be useful for treating many inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfb58a66622f9a1fc9a10be2a613ed5
https://doi.org/10.1021/acschembio.1c00681
https://doi.org/10.1021/acschembio.1c00681
Publikováno v:
Bioorganicmedicinal chemistry. 76
The overuse of antibiotics will led to the increase of drug resistance. Especially, the multidrug-resistant A. baumannii became the leading cause of nosocomial infections with high rates of morbimortality. The drug resistance of A. baumannii is great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285e80731703cbd5cb525366cae113f7
https://pubmed.ncbi.nlm.nih.gov/36442439
https://pubmed.ncbi.nlm.nih.gov/36442439