Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Yong-Kang Zhang"'
Autor:
Kirthana M. V. Sindhe, Wesley Wu, Jenny Legac, Yong-Kang Zhang, Eric E. Easom, Roland A. Cooper, Jacob J. Plattner, Yvonne R. Freund, Joseph L. DeRisi, Philip J. Rosenthal
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT New antimalarial drugs are needed. The benzoxaborole AN13762 showed excellent activity against cultured Plasmodium falciparum, against fresh Ugandan P. falciparum isolates, and in murine malaria models. To gain mechanistic insights, we selec
Externí odkaz:
https://doaj.org/article/f9067457c1d346e893d1e74840fb86f1
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 12, Pp 1791-1797 (2017)
AIM: To investigate whether curcumin suppressed corneal neovascularization (CNV) formation via inhibiting activation of Wnt/β-catenin pathway. METHODS: Suture-induced CNV was established on Sprague-Dawley (SD) rats. Curcumin were daily administrate
Externí odkaz:
https://doaj.org/article/bc45ee38288b424ea35e7732734553f2
Autor:
Ebere Sonoiki, Caroline L. Ng, Marcus C. S. Lee, Denghui Guo, Yong-Kang Zhang, Yasheen Zhou, M. R. K. Alley, Vida Ahyong, Laura M. Sanz, Maria Jose Lafuente-Monasterio, Chen Dong, Patrick G. Schupp, Jiri Gut, Jenny Legac, Roland A. Cooper, Francisco-Javier Gamo, Joseph DeRisi, Yvonne R. Freund, David A. Fidock, Philip J. Rosenthal
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Benzoxaboroles have been shown to be active against different pathogens. Here, the authors show that the benzoxaborole AN3661 inhibitsPlasmodium falciparum in vitroand in mouse models, and identify a homologue of a mammalian cleavage and polyadenylat
Externí odkaz:
https://doaj.org/article/0a61f14362894ce98b395b6ccf63a199
Autor:
Ning Zhang, Martin Zoltner, Ka-Fai Leung, Paul Scullion, Sebastian Hutchinson, Ricardo C Del Pino, Isabel M Vincent, Yong-Kang Zhang, Yvonne R Freund, Michael R K Alley, Robert T Jacobs, Kevin D Read, Michael P Barrett, David Horn, Mark C Field
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006850 (2018)
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However
Externí odkaz:
https://doaj.org/article/15b9266be10f461686b0efc0aad70326
Publikováno v:
Guoji Yanke Zazhi, Vol 14, Iss 9, Pp 1659-1662 (2014)
AIM: To investigate the characteristics of scale cataract operations and the effects and experiences of small incision extracapsular cataract extraction with intraocular lens(IOL)implantation in large-scale vision recovery action. METHODS: Four thous
Externí odkaz:
https://doaj.org/article/0f038c09843a47248e08d0d9e7341768
Publikováno v:
Materials, Vol 10, Iss 3, p 292 (2017)
Effects of laser shock processing (LSP) on the cavitation erosion resistance of laser weldments were investigated by optical microscope (OM), scanning electron microscope (SEM) observations, roughness tester, micro hardness tester, and X-ray diffract
Externí odkaz:
https://doaj.org/article/cccda65057214e06bdc47014c174f1a7
Publikováno v:
IEEE Photonics Journal, Vol 5, Iss 6, Pp 7101410-7101410 (2013)
We propose the design of a low-loss suspended core terahertz fiber with rectangular-shaped dielectric strips in the fiber cross section. The finite element method is used to analyze the characteristics of the suspended core terahertz fiber. Terahertz
Externí odkaz:
https://doaj.org/article/826e070746194c41a4eadc78deca0d15
Selected, peer reviewed papers of the 6th China-Japan International Conference on Mechatronics (CJCM 2010), Sept.10-12 2010, Zhenjiang, Jiangsu, China
Publikováno v:
The Journal of Organic Chemistry. 88:4942-4964
Carbon dioxide (CO
Autor:
Sang Hu Kim, Luke Steere, Yong-Kang Zhang, Cari McGregor, Chris Hahne, Yasheen Zhou, Chunliang Liu, Yan Cai, Haibo Zhou, Xuefei Chen, Emily Puumala, Dustin Duncan, Gerard D. Wright, C. Tony Liu, Luke Whitesell, Leah E. Cowen
Publikováno v:
ACS Chemical Biology. 17:1343-1350
With resistance to current agricultural fungicides rising, a great need has emerged for new antifungals with unexploited targets. In response, we report a novel series of diazaborines with potent activity against representative fungal plant pathogens