Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Yong-Fen Qi"'
Autor:
Jie Zhao, Ling Han, Ya-Rong Zhang, Shi-Meng Liu, Deng-Ren Ji, Rui Wang, Yan-Rong Yu, Mo-Zhi Jia, San-Bao Chai, Hui-Fang Tang, Wei Huang, Yong-Fen Qi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1204 (2024)
Diabetic cardiomyopathy (DCM), one of the most serious long-term consequences of diabetes, is closely associated with myocardial fatty acid metabolism. Carnitine palmitoyltransferase-1β (CPT-1β) is the rate-limiting enzyme responsible for β-oxidat
Externí odkaz:
https://doaj.org/article/af05f2519bd44e70ac2b0e7b41409612
Autor:
Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Shi-Meng Liu, Yan-Rong Yu, Mo-Zhi Jia, Chao-Shu Tang, Yong-Fen Qi, Wei-Wei Lu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-16 (2021)
Abstract Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has be
Externí odkaz:
https://doaj.org/article/5faf1c4b58a7429b90e5f15a4d23d640
Autor:
Shi-Meng Liu, Ya-Rong Zhang, Yao Chen, Deng-Ren Ji, Jie Zhao, Su Fu, Mo-Zhi Jia, Yan-Rong Yu, Chao-Shu Tang, Wei Huang, Ye-Bo Zhou, Yong-Fen Qi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1224 (2022)
Vascular calcification (VC) is a common pathophysiological process of chronic kidney disease (CKD). Sirtuin 3 (Sirt3), a major NAD+-dependent protein deacetylase predominantly in mitochondria, is involved in the pathogenesis of VC. We previously repo
Externí odkaz:
https://doaj.org/article/44bd70917fcc4d85835e54342c9f4aa1
Publikováno v:
Annals of Hepatology, Vol 21, Iss , Pp 100224- (2021)
Janus protein tyrosine kinase (JAK) has the ability to activate signal transducer and activator of transcription (STAT). STAT3 is a valued member of the JAK/STAT signaling pathway. In recent years, several studies have documented that STAT3 is closel
Externí odkaz:
https://doaj.org/article/9a5b161479674603b4584ff46cae0d4d
Autor:
Yu-Chen Shi, Wei-Wei Lu, Yue-Long Hou, Kun Fu, Feng Gan, Shu-Juan Cheng, Shao-Ping Wang, Yong-Fen Qi, Jing-Hua Liu
Publikováno v:
Chinese Medical Journal, Vol 131, Iss 5, Pp 532-538 (2018)
Background: Chronic kidney disease (CKD) is closely related to the cardiovascular events in vascular calcification (VC). However, little has known about the characteristics of kidney injury caused by VC. Fibroblast growth factor 21 (FGF21) is an endo
Externí odkaz:
https://doaj.org/article/e3a327ab0fc945589b68bcff46793ead
Autor:
Wen-Jia Chen, Yue Liu, Yu-Bin Sui, Hong-Tao Yang, Jin-Rui Chang, Chao-Shu Tang, Yong-Fen Qi, Jing Zhang, Xin-Hua Yin
Publikováno v:
Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background Musclin is a novel skeletal muscle-derived secretory factor considered to be a potent regulator of the glucose metabolism and therefore may contribute to the pathogenesis of obesity and insulin resistance (IR). Methods To test thi
Externí odkaz:
https://doaj.org/article/45ed00f36e044651b502f09b0035103a
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 1, Pp 35-43 (2016)
In schistosomiasis, egg-induced hepatic granuloma formation is a cytokine-mediated, predominantly CD4+ Th2 immune response that can give rise to hepatic fibrosis. Hepatic fibrosis is the main cause of increased morbidity and mortality in humans with
Externí odkaz:
https://doaj.org/article/2b2a495e2938482299af62c4b1f389ce
Autor:
Tao-Tao Li, Xiao-Yan Li, Li-Xin Jia, Jing Zhang, Wen-Mei Zhang, Yu-Lin Li, Yong-Fen Qi, Jie Du
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 2, Pp 670-682 (2016)
Background/Aims: Hypertension plays a critical role in the cardiac inflammation and injury. However, the mechanism of how hypertension causes the cardiac injury at a molecular level remains to be elucidated. Methods: RNA-Seq has been demonstrated to
Externí odkaz:
https://doaj.org/article/e90568dd2ddd453c883016f2a425b741
Publikováno v:
Chinese Medical Journal, Vol 128, Iss 23, Pp 3247-3250 (2015)
Externí odkaz:
https://doaj.org/article/c9e599aaab674ebcb794a9812589d3a5
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62001 (2013)
OBJECTIVE: Delayed or impaired reendothelialization is a major cause of stent thrombosis in the interventional treatment of coronary heart disease. T cells are involved in neointima formation of injured arteries. However, the regulated mechanism of r
Externí odkaz:
https://doaj.org/article/598c4c17c0464b1889ef0febb77d4530