Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yong-Chul Pyo"'
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 272 (2019)
The purpose of this study was to develop an oral proliposomal powder of protein using poly-l-arginine-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) (DSPE-PEG) (PLD) for enhancing cellular association upon reconstitu
Externí odkaz:
https://doaj.org/article/a7dfdbc09f014feeb8a76d4dee1e67e8
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 132 (2019)
Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic drugs (monoclonal antibodies) and small molecule drugs (nonbiologic ant
Externí odkaz:
https://doaj.org/article/ffaebd4d56734f728a0fabe0566016d5
Publikováno v:
International Journal of Pharmaceutics. 564:263-272
The purpose of this study was to improve solubility and oral bioavailability of fenofibrate via solid dispersion (SD) using a supercritical anti-solvent (SAS) process with amphipathic polymers P407 and TPGS. Solid dispersion techniques have been wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bb699217bf0ca9dff50fce3509ac4d
https://doi.org/10.1016/j.ijpharm.2019.04.051
https://doi.org/10.1016/j.ijpharm.2019.04.051
Publikováno v:
Journal of Pharmaceutical Investigation. 50:17-27
Cyclodextrins (CDs) have been used in many pharmaceutical formulations as their constitution and inherent shape present advantages for drugs with poor aqueous solubility and low bioavailability. Because CDs can act as drug carriers by forming inclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab65b52058bf33f4ad2bb7fe44893f8
https://doi.org/10.1007/s40005-019-00434-2
https://doi.org/10.1007/s40005-019-00434-2
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 196
Fenofibrate is frequently used to lower cholesterol levels in cardiovascular disease. Owing to its poor solubility and high gastrointestinal permeability, it is classified as a Biopharmaceutics Classification System class II compound. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d2d480f9bbd858a7023fb491f4dc90
https://pubmed.ncbi.nlm.nih.gov/32906001
https://pubmed.ncbi.nlm.nih.gov/32906001
Autor:
Hyun-Wook Huh, Yong-Chul Pyo, Sung-Jin Kim, Miao Wang, Hye Jin Lee, Young-Guk Na, Ki-Hyun Bang, Ji-Ho Lim, Hong-Ki Lee, Cheong-Weon Cho
Publikováno v:
Journal of Pharmaceutical Investigation. 49:271-278
Gemcitabine is used in the treatment of several solid tumors as one of anticancer nucleoside analogues and is necessary to administer high doses to achieve the desired therapeutic response. However, this treatment may be related to severe side effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df3fee357414db74a9692c50d56e602
https://doi.org/10.1007/s40005-018-0402-8
https://doi.org/10.1007/s40005-018-0402-8
Publikováno v:
Pharmaceutics
Volume 11
Issue 6
Pharmaceutics, Vol 11, Iss 6, p 272 (2019)
Volume 11
Issue 6
Pharmaceutics, Vol 11, Iss 6, p 272 (2019)
The purpose of this study was to develop an oral proliposomal powder of protein using poly-l-arginine-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) (DSPE-PEG) (PLD) for enhancing cellular association upon reconstitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acacb6185e637308c05cc4b4a35c97e
Publikováno v:
Journal of Drug Delivery Science and Technology. 57:101672
The purpose of this study was to develop oral proliposomal granules incorporating CaCl2 in order to enhance the encapsulation efficiency (EE) of protein model drug after reconstitution. Proliposomal granules were prepared by a granulation process wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a251bd1e7d8c337c092dd49b55e4e2e2
https://doi.org/10.1016/j.jddst.2020.101672
https://doi.org/10.1016/j.jddst.2020.101672
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 11, Iss 3, p 132 (2019)
Pharmaceutics, Vol 11, Iss 3, p 132 (2019)
Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic drugs (monoclonal antibodies) and small molecule drugs (nonbiologic ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a531cf19fbcc1c3bcfbbe4347489c55e
https://doi.org/10.3390/pharmaceutics11030132
https://doi.org/10.3390/pharmaceutics11030132