Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Yong-Chul Jeong"'
Autor:
Yong-Chul Jeong, Mark G. Moloney
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 3582-3627 (2015)
The synthesis, tautomerism and antibacterial activity of novel barbiturates is reported. In particular, 3-acyl and 3-carboxamidobarbiturates exhibited antibacterial activity, against susceptible and some resistant Gram-positive strains of particular
Externí odkaz:
https://doaj.org/article/99ac297b688b49c48a832a4feff1e2a7
Autor:
Yong-Chul Jeong, Mark G. Moloney
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1899-1906 (2013)
A chemical library of carboxamide-substituted tetramates designed by analogy with antibacterial natural products, a method for their rapid construction, and the evaluation of their antibacterial activity is reported.
Externí odkaz:
https://doaj.org/article/2ef6d2da9eee4d9bb81e3d2e5c37265e
Autor:
Hyo-Rim Lee, Sung-Chan Lee, Ji-Eun Lee, Seon-Mi Seo, Yong-Chul Jeong, Chan-Sik Jung, Mark G. Moloney, Il-Kwon Park
Publikováno v:
Molecules, Vol 22, Iss 9, p 1568 (2017)
Among 98 3-acyltetramic acid analogues, compounds 1c, 2c, 2f and 2g, showed >90% nematicidal activity against the pine wood nematode Bursaphelenchus xylophilus at a 10 μg/mL concentration. The nematicidal activities of compounds 1d, 1h, and 2k were
Externí odkaz:
https://doaj.org/article/b8bd48d6cece405aac26bda5a5aa4c2a
Autor:
Seon-Mi Seo, Hyo-Rim Lee, Ji-Eun Lee, Yong-Chul Jeong, Hyung-Wook Kwon, Joon-Kwan Moon, Mark G. Moloney, Il-Kwon Park
Publikováno v:
Molecules, Vol 22, Iss 7, p 1196 (2017)
Widespread concern for the occurrence of resistant strains, along with the avoidance of the use of highly toxic insecticides and their wide environmental dispersal, highlights the need for the development of new and safer pest control agents. Natural
Externí odkaz:
https://doaj.org/article/46af60147c304ec19db19366fee944fa
Autor:
Seon-Mi Seo, Yong-Chul Jeong, Il-Kwon Park, Ji-Eun Lee, Hyo-Rim Lee, Sung-Chan Lee, Mark G. Moloney, Chan-Sik Jung
Publikováno v:
Molecules, Vol 22, Iss 9, p 1568 (2017)
Molecules; Volume 22; Issue 9; Pages: 1568
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 9; Pages: 1568
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Among 98 3-acyltetramic acid analogues, compounds 1c, 2c, 2f and 2g, showed >90% nematicidal activity against the pine wood nematode Bursaphelenchus xylophilus at a 10 μg/mL concentration. The nematicidal activities of compounds 1d, 1h, and 2k were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9129c13e5a547cf9e88eca3536f764ec
https://doi.org/10.3390/molecules22091568
https://doi.org/10.3390/molecules22091568
Autor:
Yong-Chul Jeong, Mark G. Moloney, Hyo-Rim Lee, Hyung Wook Kwon, Il-Kwon Park, Seon-Mi Seo, Joon-Kwan Moon, Ji-Eun Lee
Publikováno v:
Molecules, Vol 22, Iss 7, p 1196 (2017)
Molecules; Volume 22; Issue 7; Pages: 1196
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 7; Pages: 1196
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Widespread concern for the occurrence of resistant strains, along with the avoidance of the use of highly toxic insecticides and their wide environmental dispersal, highlights the need for the development of new and safer pest control agents. Natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ec60e1597018ebf02309cb0d308fdd
https://doi.org/10.3390/molecules22071196
https://doi.org/10.3390/molecules22071196
Publikováno v:
Chem. Sci.. 4:1008-1015
The application of natural product inspired synthesis has identified novel antibacterial tetramic acids which exhibit wide ranging antibacterial activity, and which provide potential lead structures for antibacterial drug discovery. Their phenotypic
Inspired by the core fragment of antibacterial natural products such as streptolydigin, 3-acyltetramic acids and 3-acylpiperidine-2,4-diones have been synthesised from the core heterocycle by direct acylation with the substituted carboxylic acids usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3909b920dc987a04240061197c2ed1
https://doi.org/10.1002/cmdc.201402093
https://doi.org/10.1002/cmdc.201402093
Autor:
Mark G. Moloney, Christopher J. Matthews, Chloe A. Holloway, Muhammad Yaqoob, Christine F. Roberts, Yong-Chul Jeong
Publikováno v:
Chemical Biology & Drug Design. 78:229-235
Modification of the ring nucleus of tetramic acids derived from serine gives chiral heterocyclic libraries that exhibit antibacterial activity, and correlation with various physicochemical parameters indicates that chiral tetramic acids may provide a
Publikováno v:
Bulletin of the Korean Chemical Society. 32:1063-1066
For example, the biological activitiesof sulfoxide containing drugs such as omeprazole arestrongly related to the chirality of the sulfoxide group; forthis reason, esomeprazole, the enantiomerically pure form ofomeprazole, was later developed. There