Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Yong-Chuan Wong"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51108 (2012)
The ATM/ATR DNA damage checkpoint functions in the maintenance of genetic stability and some missense variants of the ATM gene have been shown to confer a moderate increased risk of prostate cancer. However, whether inactivation of this checkpoint co
Externí odkaz:
https://doaj.org/article/c050eb3dacc44517a1e56d2625096186
Autor:
Sze-Ue Luk, Terence Kin-Wah Lee, Ji Liu, Davy Tak-Wing Lee, Yung-Tuen Chiu, Stephanie Ma, Irene Oi-Lin Ng, Yong-Chuan Wong, Franky Leung Chan, Ming-Tat Ling
Publikováno v:
PLoS ONE, Vol 6, Iss 6 (2011)
Externí odkaz:
https://doaj.org/article/a2133b58113a44bea96cfb4e6d060ee5
Autor:
Sze-Ue Luk, Terence Kin-Wah Lee, Ji Liu, Davy Tak-Wing Lee, Yung-Tuen Chiu, Stephanie Ma, Irene Oi-Lin Ng, Yong-Chuan Wong, Franky Leung Chan, Ming-Tat Ling
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19804 (2011)
Recent evidence suggested that prostate cancer stem/progenitor cells (CSC) are responsible for cancer initiation as well as disease progression. Unfortunately, conventional therapies are only effective in targeting the more differentiated cancer cell
Externí odkaz:
https://doaj.org/article/5ef2290c5c0348ea9bb63341bc6696d1
Autor:
Yong-Chuan Wong, Ming-Tat Ling, Xianghong Wang, Kwan Man, Kwok-Wah Chan, Hiu-Fung Yuen, Yung-Tuen Chiu, Chee-Wai Chua
Purpose: Previously, FTY720 was found to possess potent anticancer effects on various types of cancer. In the present study, we aimed to first verify the role of Runx2 in prostate cancer progression and metastasis, and, subsequently, assessed if FTY7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aec801540839e5382bbe44e1abd0b4
https://doi.org/10.1158/1078-0432.c.6517725.v1
https://doi.org/10.1158/1078-0432.c.6517725.v1
Autor:
Yong-Chuan Wong, Ming-Tat Ling, Xianghong Wang, Kwan Man, Kwok-Wah Chan, Hiu-Fung Yuen, Yung-Tuen Chiu, Chee-Wai Chua
Supplementary Data from Suppression of Androgen-Independent Prostate Cancer Cell Aggressiveness by FTY720: Validating Runx2 as a Potential Antimetastatic Drug Screening Platform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d352e7435d0415c77ea5bee180c400
https://doi.org/10.1158/1078-0432.22440390.v1
https://doi.org/10.1158/1078-0432.22440390.v1
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Rev7p has been suggested to play an important role in regulating DNA damage response in yeast, and recently, the human homologue (i.e., MAD2B) has been identified, which shares significant homology to the mitotic checkpoint protein MAD2. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620d50eb49190cd30b811c107961499f
https://doi.org/10.1158/0008-5472.c.6494960.v1
https://doi.org/10.1158/0008-5472.c.6494960.v1
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Supplementary Figure 1 from Inactivation of Human MAD2B in Nasopharyngeal Carcinoma Cells Leads to Chemosensitization to DNA-Damaging Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae2cc0bbea718a5727a4254c59ecaec
https://doi.org/10.1158/0008-5472.22366031
https://doi.org/10.1158/0008-5472.22366031
Autor:
Xianghong Wang, Dong-Yan Jin, Sai Wah Tsao, Yong Chuan Wong, Ming-Tat Ling, John M. Nicholls, Xin-Yuan Guan, Liang Hu, Wen Deng, Qi Wang, Abel C.S. Chun, Hiu Wing Cheung
Supplementary Figure Legend from Inactivation of Human MAD2B in Nasopharyngeal Carcinoma Cells Leads to Chemosensitization to DNA-Damaging Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355951bba749d67b3024e8b397b367b6
https://doi.org/10.1158/0008-5472.22366028
https://doi.org/10.1158/0008-5472.22366028
Autor:
Xianghong Wang, Yong-Chuan Wong, Carlotta Glackin, Franky L. Chan, Kwok W. Chan, Chee Wai Chua, Xiaomeng Zhang, Chun Zhou, Tracy C.M. Lau, Tak-Wing Lee, Ming-Tat Ling, Wai Kei Kwok
Supplementary Figure S1 from Up-Regulation of TWIST in Prostate Cancer and Its Implication as a Therapeutic Target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd35918b8d0f23a083259dd7af464dba
https://doi.org/10.1158/0008-5472.22363665.v1
https://doi.org/10.1158/0008-5472.22363665.v1
Autor:
Xianghong Wang, Yong-Chuan Wong, Carlotta Glackin, Franky L. Chan, Kwok W. Chan, Chee Wai Chua, Xiaomeng Zhang, Chun Zhou, Tracy C.M. Lau, Tak-Wing Lee, Ming-Tat Ling, Wai Kei Kwok
Androgen-independent metastatic prostate cancer is the main obstacle in the treatment of this cancer. Unlike a majority of solid cancers, prostate cancer usually shows poor response to chemotherapeutic drugs. In this study, we have shown a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02adbdbd7215ed34dd7a990abb960ae3
https://doi.org/10.1158/0008-5472.c.6493827
https://doi.org/10.1158/0008-5472.c.6493827