Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Yong-Chen Lu"'
Autor:
Anna Pasetto, Yong-Chen Lu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/2459e15df3e94d3bbd012f4bfec582d2
Autor:
Lu Dai, Yong-Chen Lu, Jungang Chen, Karlie Plaisance-Bonstaff, Shengyu Mu, J. Craig Forrest, Denise Whitby, Steven R. Post, Zhiqiang Qin
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Kaposi’s Sarcoma (KS) caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) continues to be the most common AIDS-associated tumor. Involvement of the oral cavity represents one of the most common clinical manifestations of this tumor. Numerous
Externí odkaz:
https://doaj.org/article/1bc13e3b4ab649889fbd95362bab20d8
Autor:
Takeo Shibata, Sumit Shah, Teresa Evans, Hannah Coleman, Benjamin J. Lieblong, Horace J. Spencer, Charles M. Quick, Toshiyuki Sasagawa, Owen W. Stephens, Erich Peterson, Donald Johann, Yong-Chen Lu, Mayumi Nakagawa
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Advances in high-throughput sequencing have revolutionized the manner with which we can study T cell responses. We describe a woman who received a human papillomavirus (HPV) therapeutic vaccine called PepCan, and experienced complete resolution of he
Externí odkaz:
https://doaj.org/article/29abd501a0764a94bfe5b6d0ff3879b8
Autor:
Steven A Rosenberg, Paul F Robbins, Zhili Zheng, Todd D Prickett, Jared J Gartner, Yong-Chen Lu, Frank J Lowery
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Recognition of neoantigens by T cells plays a major role in cancer immunotherapy. Identification of neoantigen-specific T-cell receptors (TCRs) has become a critical research tool for studying T cell-mediated responses after immunotherapy.
Externí odkaz:
https://doaj.org/article/f63bc5db04c54d5d82a8bb69ef9cf4c3
Autor:
Anna Pasetto, Yong-Chen Lu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cells have been known to be the driving force for immune response and cancer immunotherapy. Recent advances on single-cell sequencing techniques have empowered scientists to discover new biology at the single-cell level. Here, we review the single-
Externí odkaz:
https://doaj.org/article/6c5cf338d89246f1bdc01a44cd6a7e59
Autor:
Gal Cafri, Rami Yossef, Anna Pasetto, Drew C. Deniger, Yong-Chen Lu, Maria Parkhurst, Jared J. Gartner, Li Jia, Satyajit Ray, Lien T. Ngo, Mohammad Jafferji, Abraham Sachs, Todd Prickett, Paul F. Robbins, Steven A. Rosenberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Adoptive cell therapy (ACT) using neoantigen-specific T cells can lead to tumor regression. Here the authors use an in vitro stimulation approach to isolate tumor specific memory T cells from peripheral blood of metastatic epithelial cancer patients
Externí odkaz:
https://doaj.org/article/4abe5b00b67f409c95fdd11f690fc2b9
Publikováno v:
Cancers, Vol 13, Iss 23, p 6061 (2021)
Patients with metastatic cutaneous melanoma have experienced significant clinical responses after checkpoint blockade immunotherapy or adoptive cell therapy. Neoantigens are mutated proteins that arise from tumor-specific mutations. It is hypothesize
Externí odkaz:
https://doaj.org/article/2267696d852f41b6ba45a89587cf3ec2
Autor:
Panagiota Maravelia, Daniela Nascimento Silva, Giulia Rovesti, Michael Chrobok, Per Stål, Yong-Chen Lu, Anna Pasetto
Publikováno v:
Cancers, Vol 13, Iss 17, p 4334 (2021)
Hepatocellular carcinoma (HCC) is one of the deadliest cancer types worldwide. HCC is often diagnosed at a late stage when the therapeutic options are very limited. However, even at the earlier stages, the best treatment is liver transplantation, sur
Externí odkaz:
https://doaj.org/article/7ce9ee365e0a4ba2abc4ccc2b6de2413
Autor:
Sanghyun P. Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger, Frank J. Lowery, Maria R. Parkhurst, Lien T. Ngo, Satyajit Ray, Yong F. Li, Victoria Hill, Maria Florentin, Robert V. Masi, Biman C. Paria, Noam Levin, Alakesh Bera, Elizabeth A. Hedges, Agnes Choi, Praveen D. Chatani, Anup Y. Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D. Prickett, Li Jia, Jonathan M. Hernandez, Chuong D. Hoang, Paul F. Robbins, Stephanie L. Goff, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
Publikováno v:
Cancer Immunology Research. 10:932-946
Adoptive cellular therapy (ACT) targeting neoantigens can achieve durable clinical responses in patients with cancer. Most neoantigens arise from patient-specific mutations, requiring highly individualized treatments. To broaden the applicability of
Autor:
Ching-Cheng Lin, Ti-Yung Chang, Yong-Chen Lu, Yun-Syuan Wu, Wei Huang, Wei-Chi Lo, Guan-Fu Liu, Wei-Chan Hsu, Pamela S. Ohashi, Tak W. Mak, Jong-Ling Fuh, Hui-Chen Chen, Der-Cherng Tarng, Nien-Jung Chen
Publikováno v:
Journal of Molecular Medicine. 100:917-931
Chronic kidney disease (CKD) is a global public health issue. CKD is caused by the infiltration of various myeloid cell types into renal tissue, resulting in renal fibrosis and tubular atrophy. Unilateral ureteral obstruction (UUO) surgery in mice is