Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Yong jiang Hei"'
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Akademický článek
Challenges in developing a validated biomarker for angiogenesis inhibitors: the motesanib experience.
Autor: Michael B Bass, Bin Yao, Yong-Jiang Hei, Yining Ye, Gerard J Davis, Michael T Davis, Barbara A Kaesdorf, Sabrina S Chan, Scott D Patterson
Publikováno v: PLoS ONE, Vol 9, Iss 10, p e108048 (2014)
We sought to develop placental growth factor as a predictive pharmacodynamic biomarker for motesanib efficacy as first-line therapy in patients with advanced nonsquamous non-small-cell lung cancer.Placental growth factor was evaluated at baseline and
Externí odkaz: https://doaj.org/article/d3ebf97e97f0499b9c74773db40ee917
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3
Predictive Value of Bone Resorption and Formation Markers in Cancer Patients With Bone Metastases Receiving the Bisphosphonate Zoledronic Acid
Autor: Janet E. Brown, Matthew Smith, Richard J. Cook, John W. Seaman, Pierre Major, Ker Ai Lee, Ming Zheng, F. Saad, Robert E. Coleman, Allan Lipton, Yong Jiang Hei
Publikováno v: Journal of Clinical Oncology. 23:4925-4935
Purpose Three large, randomized trials of patients with bone metastases recently demonstrated that zoledronic acid reduces the risk of skeletal-related events. These trials provide an opportunity for investigating the correlation between bone metabol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4941b2c1873ae0e2e9eaa59074c36b3
https://doi.org/10.1200/jco.2005.06.091
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6
[Untitled]
Autor: John H. McNeill, Xunsheng Chen, Sepehr Farahbakhshian, Yong-jiang Hei, Mary L. Battell
Publikováno v: Molecular and Cellular Biochemistry. 178:367-375
To explore the mechanism underlying the insulin-mimetic actions of vanadium and selenium we examined their effects on the mitogen activated protein/myelin basic protein kinases (MAPK) and ribosomal S6 protein kinases, which are among the best charact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::042dc659069bda10267cc56adc066427
https://doi.org/10.1023/a:1006819906820
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Skeletal Muscle Mitogen-Activated Protein Kinases and Ribosomal S6 Kinases: Suppression in Chronic Diabetic Rats and Reversal by Vanadium
Autor: Yong-jiang Hei, Steven L. Pelech, Xunsheng Chen, Jack Diamond, John H. McNeill
Publikováno v: Diabetes. 44:1147-1155
The mitogen-activated protein (MAP) kinases and ribosomal S6 protein kinases in the skeletal muscle of insulin-resistant long-term (2 and 6 months' duration) diabetic rats were investigated to understand further the changes in insulin intracellular s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385b670750b8c7de842d271065fc0159
https://doi.org/10.2337/diab.44.10.1147
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Outcomes by hypomagnesemia (hypomag) in the randomized phase III ASPECCT trial of patients (pts) with chemofractory wild-type (WT) KRAS exon 2 metastatic colorectal cancer (mCRC)
Autor: Sergei Tjulandin, Anne Thomas, Tae Won Kim, Stefano Cascinu, Xuesong Guan, Timothy J. Price, Yong Jiang Hei, Marc Peeters, Tien Hoang, Attili Venkatasatya Suresh, Jin Li, Paul Ruff
Publikováno v: ResearcherID
507 Background: ASPECCT demonstrated that panitumumab (pmab) was noninferior to cetuximab (cmab) for overall survival (OS). Ad hoc analyses from ASPECCT suggested that hypomag was associated with better outcomes for pmab and cmab (Price 2015). Howeve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5e99625b3a69dee69abeb71d79b6b8
https://doi.org/10.1200/jco.2016.34.4_suppl.507
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Efficacy of panitumumab (pmab) vs. cetuximab (cmab) in patients (pts) with wild-type (WT) KRAS exon 2 metastatic colorectal cancer (mCRC) treated with prior bevacizumab (bev): Results from ASPECCT
Autor: Yong Jiang Hei, Xuesong Guan, Jin Li, Attili Venkatasatya Suresh, Sergei Tjulandin, Paul Ruff, Tae Won Kim, Anne Thomas, Stefano Cascinu, Tien Hoang, Marc Peeters, Timothy J. Price
Publikováno v: Journal of Clinical Oncology. 34:519-519
519 Background: The phase 3 ASPECCT trial of pts with chemorefractory WT KRAS exon 2 mCRC demonstrated that pmab was noninferior to cmab for overall survival (OS). A previous subgroup analysis of hazard ratios (HRs) suggested that pts who had receive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87d1aa9a534e4ee32749364f47217bb6
https://doi.org/10.1200/jco.2016.34.4_suppl.519
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10
Purification and characterization of a novel ribosomal S6 kinase from skeletal muscle of insulin-treated rats
Autor: Steven L. Pelech, Jack Diamond, John H. McNeill, Yong-jiang Hei, Xunsheng Chen
Publikováno v: Journal of Biological Chemistry. 269:7816-7823
The predominant 40 S ribosomal protein S6 kinase in skeletal muscle extracts from insulin-treated rats was purified over 10,000-fold to near homogeneity with approximately 4.5% recovery of starting activity. This S6 kinase was resolved from the catal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a4d6a231d77d9b8b51f5a2c07e83b81
https://doi.org/10.1016/s0021-9258(17)37359-3
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