Zobrazeno 1 - 10
of 1 929
pro vyhledávání: '"Yong Y. He"'
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 881-889 (2005)
Growing evidence suggests that cells undergo apoptosis after spinal cord injury (SCI). However, little is known about the early events that trigger apoptosis in the contused cord. The BH3-only subfamily of pro-apoptotic regulators (e.g., bim, bad, an
Externí odkaz:
https://doaj.org/article/094f665aa7da4fb88ed9771069a48282
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 881-889 (2005)
Growing evidence suggests that cells undergo apoptosis after spinal cord injury (SCI). However, little is known about the early events that trigger apoptosis in the contused cord. The BH3-only subfamily of pro-apoptotic regulators (e.g., bim, bad, an
Formalin fixation alters water diffusion coefficient magnitude but not anisotropy in infarcted brain
Autor:
Sheng-Kwei Song, Jeffrey J. Neil, Yong Y. He, Robert E. Schmidt, Chung Y. Hsu, Shu-Wei Sun, Hsiao Fang Liang
Publikováno v:
Magnetic Resonance in Medicine. 53:1447-1451
This study was designed to determine whether formalin fixation alters diffusion parameters in the infarcted brain. Diffusion tensor images were obtained from anesthetized mice 1 hr after middle cerebral artery occlusion and repeated after formalin fi
Autor:
Albert Y. Sun, Yong Y. He, Wai Mui Cheung, Grace Y. Sun, Chung Y. Hsu, Qun Wang, Jean Ju Chen, Teng-Nan Lin, Agnes Simonyi, Jan Xu
Publikováno v:
Journal of Neurochemistry. 90:637-645
Although mRNA expression of group IIA secretory phospholipase A2 (sPLA2-IIA) has been implicated in responses to injury in the CNS, information on protein expression remains unclear. In this study, we investigated temporal and spatial expression of s
Publikováno v:
Journal of Neurochemistry. 73:2218-2221
Mutation in the Nurr1 gene, a member of the nuclear receptor superfamily, causes selective agenesis of dopaminergic neurons in the midbrain of null mice. Homozygous Nurr1 knockout mice (Nurr1-/-) die 1 day after birth, but heterozygous mice (Nurr1 +/
Autor:
Kilichan Gurleyik, Richard P. Paczynski, Ramesh Venkatesan, Chung Y. Hsu, Weili Lin, William J. Powers, Yong Y. He
Publikováno v:
Magnetic Resonance in Medicine. 43:146-150
Using a magnetic resonance (MR) imaging method, absolute measurements of in vivo brain water content were obtained in 15 male Long Evans rats that underwent a 90-min focal cerebral ischemia. A strong linear relationship (r = 0.80) with a slope of 1 w
Publikováno v:
Annals of Neurology. 43:664-669
The diazoxide derivative IDRA 21 and other positive modulators of (AMPA)-type glutamate receptors are considered potential memory-enhancing agents. However, AMPA receptor activation contributes to CA1 hippocampal neuron damage from global ischemia in
Publikováno v:
Stroke. 28:1437-1444
Background and Purpose Repeated use of mannitol in the setting of ischemic infarction is a controversial and poorly defined therapeutic intervention. The purpose of this study was to examine the effects of repeated mannitol infusions on brain water c
Publikováno v:
Science. 272:1013-1016
Zinc is present in presynaptic nerve terminals throughout the mammalian central nervous system and likely serves as an endogenous signaling substance. However, excessive exposure to extracellular zinc can damage central neurons. After transient foreb
Publikováno v:
Scopus-Elsevier
Infarct volume is one of the common indexes for assessing the extent of ischemic brain injury following focal cerebral ischemia. Accuracy in the measurement of infarct volume is compounded by postischemic brain edema that may increase brain volume in