Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yong Xian Hu"'
Publikováno v:
ImmunoMedicine, Vol 2, Iss 1, Pp n/a-n/a (2022)
Abstract Chimeric antigen receptors (CAR) T‐cell therapy is one of the most effective treatments in curing hematologic malignancies. Besides the four CD19 CAR T‐cells therapy recently approved by the US Food and Drug Administration (FDA), CD20 CA
Externí odkaz:
https://doaj.org/article/32939fc747924d238e8275448fc36a1f
Autor:
Ting-Ting Yang, Ye Meng, De-Lin Kong, Guo-Qing Wei, Ming-Ming Zhang, Wen-Jun Wu, Ji-Min Shi, Yi Luo, Yan-Min Zhao, Jian Yu, Rui-Rui Jing, Meng-Yu Zhao, Hou-Li Zhao, He Huang, Yong-Xian Hu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionChimeric antigen receptor (CAR) T-cell (CAR-T) therapy followed by haploidentical hematopoietic stem cell transplantation (haplo-HSCT) markedly improves the long-term survival of patients with refractory/relapsed (R/R) B-cell acute lympho
Externí odkaz:
https://doaj.org/article/d2dade5d80084fd29b673875840c94b1
Autor:
Shu-Yi Ding, Yin Cheng, Yi-Jie Huang, Xin Gao, Jia-Li Yan, Lin-Qin Wang, Hou-Li Zhao, Rui Wang, Sang-Sang Chen, Tian-Li Teng, Nian Liu, Ming-Ming Zhang, Ai-Yun Jin, Yong-Xian Hu
Purpose To ascertain the risk factors and prevalence of non-infectious diarrhea among participants with multiple myeloma who treated with chimeric antigen receptor T-cell immunotherapy. Methods This study enrolled 88 patients with multiple myeloma wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13b60fcf5b0d4af1a53442c0e7be9b9
https://doi.org/10.21203/rs.3.rs-2528277/v1
https://doi.org/10.21203/rs.3.rs-2528277/v1
Publikováno v:
Current Medical Science. 41:420-430
Chimeric antigen receptor T (CAR-T) cell therapy is the novel treatment strategy for hematological malignancies such as acute lymphoblastic leukemia (ALL), lymphoma and multiple myeloma. However, treatment-related toxicities such as cytokine release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e5c9823eaf3ba67b21f0ad1645e9aa
https://doi.org/10.1007/s11596-021-2391-5
https://doi.org/10.1007/s11596-021-2391-5
Publikováno v:
Journal of Zhejiang University-SCIENCE B. 21:29-41
Multiple myeloma (MM), considered an incurable hematological malignancy, is characterized by its clonal evolution of malignant plasma cells. Although the application of autologous stem cell transplantation (ASCT) and the introduction of novel agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe24c920d358b900cb17ae21f240375a
https://doi.org/10.1631/jzus.b1900351
https://doi.org/10.1631/jzus.b1900351
Autor:
Ting-Ting Yang, Ye Meng, De-Lin Kong, Guo-Qing Wei, Ming-Ming Zhang, Wen-Jun Wu, Ji-Min Shi, Yi Luo, Yan-Min Zhao, Jian Yu, Rui-Rui Jing, Meng-Yu Zhao, Hou-Li Zhao, He Huang, Yong-Xian Hu
Publikováno v:
Frontiers in Immunology; 8/30/2022, Vol. 13, p1-13, 13p
Autor:
Kang Ni Wu, Hua Rui Fu, Yu Lin Xu, Li Zhen Liu, He Huang, Ji Min Shi, Yi Luo, Ya Min Tan, Li Fei Zhang, Hao Wen Xiao, Zhen Cai, Yong Xian Hu, Xiaohong Yu, Li Xia Sheng
Publikováno v:
Stem Cells and Development. 21:177-180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e364f9578b05b65678d8a68b852a5a1
https://doi.org/10.1089/scd.2011.0308
https://doi.org/10.1089/scd.2011.0308
Autor:
Kang Yu, Bin Liang, Song-Fu Jiang, Yinxia Tan, Zhi-jian Shen, Yong-Xian Hu, Hong-Lan Qian, Da-Ming Shan
Publikováno v:
Leukemia & Lymphoma. 49:1368-1373
One of the approaches to make anti-CD20 antibody more efficient is to express this antibody on the surface of T cells. scFv from anti-CD20 antibody has been expressed on T cell surface to bind to CD20 positive cells and CD3zeta has been expressed as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4fe48517b642c0c5e4dddbfe9bbaf7
https://doi.org/10.1080/10428190802064958
https://doi.org/10.1080/10428190802064958
Autor:
Hong-Lan, Qian, Kang, Yu, Zhi-Jian, Shen, Bin, Liang, Sheng, Luo, Chong-Yun, Xing, Yong-Xian, Hu
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 26(4)
To construct anti-CD20scFv/CD80/CD28/zeta recombinant gene modified T cells, test its effectiveness of eradicating CD20 positive primary chronic lymphocytic leukemia (CLL) cells and provide a promising tool for tumor adoptive immunotherapy.The recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b27648188c46d02f754847bcdd7a454f
https://pubmed.ncbi.nlm.nih.gov/21328981
https://pubmed.ncbi.nlm.nih.gov/21328981
Autor:
Yong-Xian, Hu, Kang, Yu, Ying-Xia, Tan, Zhi-Jian, Shen, Hong-Lan, Qian, Bin, Liang, Da-Ming, Shan
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 24(3)
To construct recombinant retroviruses expressing anti-CD20 scFv/CD80/CD28/zeta gene and detect its expression in Jurkat cells.CD28-zetacDNA were amplified from plasmids pBULLET and inserted into pLNCX vector that contained anti-CD20 scFv/CD80 gene. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5193c3b6c770180031b623a8df942e23
https://pubmed.ncbi.nlm.nih.gov/21141599
https://pubmed.ncbi.nlm.nih.gov/21141599