Zobrazeno 1 - 10
of 610
pro vyhledávání: '"Yong Tang Zheng"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121666 (2015)
TRIMCyp is a fusion protein consisting of the TRIM5 gene product and retrotransposed Cyclophilin A (CypA). Two primate TRIMCyp fusion proteins with varying anti-HIV-1 activities independently evolved in owl monkeys and Old World monkeys. In addition,
Externí odkaz:
https://doaj.org/article/f1469be542084d9aa8636461acb1f064
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103233- (2024)
Externí odkaz:
https://doaj.org/article/fdb788afa3ee425da4db8686a332518d
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199313- (2024)
Human immunodeficiency virus-1 (HIV-1) infection can cause chronic activation, exhaustion, and anergy of the immune system. Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint molecule, which plays an important role in immune
Externí odkaz:
https://doaj.org/article/ef8b8c05ebb84418812a7f57a9f69e05
Autor:
Ying Lu, Fan Shen, Wen-Qiang He, An-Qi Li, Ming-Hua Li, Xiao-Li Feng, Yong-Tang Zheng, Wei Pang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3339-3351 (2023)
The continuously emerging SARS-CoV-2 variants pose a great challenge to the efficacy of current drugs, this necessitates the development of broad-spectrum antiviral drugs. In the previous study, we designed a recombinant protein, heptad repeat (HR) 1
Externí odkaz:
https://doaj.org/article/87c99dfaaec643baae6ab94320202fd5
Autor:
Rufei Duan, Hongping Zhang, Jing Yu, Sisi Deng, Haijun Yang, Yong-Tang Zheng, Yunchao Huang, Fanghui Zhao, Hongying Yang
Publikováno v:
BMC Women's Health, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Gynecological cancer will become a more important public health problem in future years but limited evidence on gynecological cancer burden in China. Methods We extracted age-specific rate of cancer cases and deaths during 2007–
Externí odkaz:
https://doaj.org/article/91d68785b36246dcae8c1033da086e0e
Autor:
Sunil K. Ahuja, Muthu Saravanan Manoharan, Grace C. Lee, Lyle R. McKinnon, Justin A. Meunier, Maristella Steri, Nathan Harper, Edoardo Fiorillo, Alisha M. Smith, Marcos I. Restrepo, Anne P. Branum, Matthew J. Bottomley, Valeria Orrù, Fabio Jimenez, Andrew Carrillo, Lavanya Pandranki, Caitlyn A. Winter, Lauryn A. Winter, Alvaro A. Gaitan, Alvaro G. Moreira, Elizabeth A. Walter, Guido Silvestri, Christopher L. King, Yong-Tang Zheng, Hong-Yi Zheng, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Keith R. Fowke, Paul N. Harden, Kathryn J. Wood, Martin T. Ferris, Jennifer M. Lund, Mark T. Heise, Nigel Garrett, Kristen R. Canady, Salim S. Abdool Karim, Susan J. Little, Sara Gianella, Davey M. Smith, Scott Letendre, Douglas D. Richman, Francesco Cucca, Hanh Trinh, Sandra Sanchez-Reilly, Joan M. Hecht, Jose A. Cadena Zuluaga, Antonio Anzueto, Jacqueline A. Pugh, South Texas Veterans Health Care System COVID-19 team, Brian K. Agan, Robert Root-Bernstein, Robert A. Clark, Jason F. Okulicz, Weijing He
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-31 (2023)
Abstract Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined as the capacity to preserve and/
Externí odkaz:
https://doaj.org/article/2d05c47c46834fc38503fbfb37c7eb1f
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Tripartite motif-containing protein 5α (TRIM5α) is generally known to block the postentry events of HIV-1. Here, we report an uncharacterized role for TRIM5α in the maintenance of viral latency. Knockdown of TRIM5α potentiates the transc
Externí odkaz:
https://doaj.org/article/46e1520c060a49c399947f0fb7761cb5
Autor:
Hui Han, Rong-Hua Luo, Xin-Yan Long, Li-Qiong Wang, Qian Zhu, Xin-Yue Tang, Rui Zhu, Yi-Cheng Ma, Yong-Tang Zheng, Cheng-Gang Zou
Publikováno v:
eLife, Vol 13 (2024)
Angiotensin-converting enzyme 2 (ACE2) is a major cell entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The induction of ACE2 expression may serve as a strategy by SARS-CoV-2 to facilitate its propagation. However, the
Externí odkaz:
https://doaj.org/article/850dd6a83bc34e6188c2142e3e835bad
Autor:
Yanpeng Li, Peng Zhang, Mei Ye, Ren-Rong Tian, Na Li, Le Cao, Yingying Ma, Feng-Liang Liu, Yong-Tang Zheng, Chiyu Zhang
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 5, Pp 1015-1019 (2023)
We identified a novel circovirus (human-associated circovirus 2 [HuCV2]) from the blood of 2 intravenous drug users in China who were infected with HIV-1, hepatitis C virus, or both. HuCV2 is most closely related to porcine circovirus 3. Our findings
Externí odkaz:
https://doaj.org/article/1d853e434fa34a309c3571b721b51fb4
Autor:
Wei Yang, Li-Bo Liu, Feng-Liang Liu, Yan-Hua Wu, Zi-Da Zhen, Dong-Ying Fan, Zi-Yang Sheng, Zheng-Ran Song, Jia-Tong Chang, Yong-Tang Zheng, Jing An, Pei-Gang Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Zika virus (ZIKV) is a potential threat to male reproductive health but the mechanisms underlying its influence on testes during ZIKV infection remain obscure. To address this question, we perform single-cell RNA sequencing using testes from
Externí odkaz:
https://doaj.org/article/3c4f912680a4472e8b5f20a294f85fab