Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Yong Tae Kwon"'
Autor:
Jihoon Lee, Ki Woon Sung, Eun-Jin Bae, Dabin Yoon, Dasarang Kim, Jin Saem Lee, Da-ha Park, Daniel Youngjae Park, Su Ran Mun, Soon Chul Kwon, Hye Yeon Kim, Joo-Ok Min, Seung-Jae Lee, Young Ho Suh, Yong Tae Kwon
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-21 (2023)
Abstract Background There are currently no disease-modifying therapeutics for Parkinson’s disease (PD). Although extensive efforts were undertaken to develop therapeutic approaches to delay the symptoms of PD, untreated α-synuclein (α-syn) aggreg
Externí odkaz:
https://doaj.org/article/63f416f66800494bb59e84f43141648f
Autor:
Prashanta Silwal, Young Jae Kim, Yoon Jee Lee, In Soo Kim, Sang Min Jeon, Taylor Roh, Jin Kyung Kim, Min Joung Lee, Jun Young Heo, Doo Sin Jo, Sang-Hee Lee, Dong-Hyung Cho, Jin Man Kim, Yong Tae Kwon, Eun-Kyeong Jo
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 2, Pp 333-346 (2023)
Sepsis: chemical modulation of selective autophagy alleviates systemic inflammation Sepsis is a life-threatening condition that occurs when the body’s response to infection damages its own organs. Autophagy protects the body by degrading harmful ma
Externí odkaz:
https://doaj.org/article/d50e91f648ef4a7099705e8a8cceed43
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 70-74 (2022)
Cell survival depends on dynamic interactions among the signaling pathways that control the endoplasmic reticulum (ER) stress response, macroautophagy/autophagy and apoptotic cell death. Our recent study reported an association of cytoplasmic SQSTM1/
Externí odkaz:
https://doaj.org/article/b24781601f794a34b35d35b8c3222a3a
Autor:
Jihoon Lee, Ki Woon Sung, Eun-Jin Bae, Dabin Yoon, Dasarang Kim, Jin Saem Lee, Da-ha Park, Daniel Youngjae Park, Su Ran Mun, Soon Chul Kwon, Hye Yeon Kim, Joo-Ok Min, Seung-Jae Lee, Young Ho Suh, Yong Tae Kwon
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0f49e7ee9cb9412588f7f04d9182eeec
Autor:
Chang Hoon Ji, Hee Yeon Kim, Min Ju Lee, Ah Jung Heo, Daniel Youngjae Park, Sungsu Lim, Seulgi Shin, Woo Seung Yang, Chang An Jung, Kun Young Kim, Eun Hye Jeong, Sun Ho Park, Su Bin Kim, Su Jin Lee, Jeong Eun Na, Ji In Kang, Hyung Min Chi, Hyun Tae Kim, Yun Kyung Kim, Bo Yeon Kim, Yong Tae Kwon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Targeted protein degradation is a promising approach for basic research and therapeutic applications. Here, the authors develop a targeted protein degradation platform called AUTOTAC to degrade oncoproteins and neurodegeneration-associated proteins v
Externí odkaz:
https://doaj.org/article/b40a23bb612c4deeb02c237334426aad
Publikováno v:
Bio-Protocol, Vol 13, Iss 2 (2023)
Targeted protein degradation (TPD) facilitates the selective elimination of unwanted and pathological cellular cargoes via the proteasome or the lysosome, ranging from proteins to organelles and pathogens, both within and outside the cell. Currently,
Externí odkaz:
https://doaj.org/article/4760170ab5b9425f8839fdfe45ea5208
Autor:
Su Hyun Lee, Won Jin Cho, Abdo J. Najy, Allen-Dexter Saliganan, Tri Pham, Joseph Rakowski, Brian Loughery, Chang Hoon Ji, Wael Sakr, Seongho Kim, Ikuko Kato, Weon Kuu Chung, Harold E. Kim, Yong Tae Kwon, Hyeong-Reh C. Kim
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Abstract The autophagy–lysosome pathway and apoptosis constitute vital determinants of cell fate and engage in a complex interplay in both physiological and pathological conditions. Central to this interplay is the archetypal autophagic cargo adapt
Externí odkaz:
https://doaj.org/article/e89bcaa470b548bd85c6df68854a1dd1
Autor:
Yo Sep Hwang, Hee Jun Cho, Eun Sun Park, Jeewon Lim, Hyang Ran Yoon, Jong-Tae Kim, Suk Ran Yoon, Haiyoung Jung, Yong-Kyung Choe, Yong-Hoon Kim, Chul-Ho Lee, Yong Tae Kwon, Bo Yeon Kim, Hee Gu Lee
Publikováno v:
Cells, Vol 11, Iss 24, p 4101 (2022)
Kallikrein-related peptidase (KLK)6 is associated with inflammatory diseases and neoplastic progression. KLK6 is aberrantly expressed in several solid tumors and regulates cancer development, metastatic progression, and drug resistance. However, the
Externí odkaz:
https://doaj.org/article/1af1ee17fb2842c29dbef30351045c9d
Autor:
Nak-Kyun Soung, Hye-Min Kim, Yukihiro Asami, Dong Hyun Kim, Yangrae Cho, Ravi Naik, Yerin Jang, Kusic Jang, Ho Jin Han, Srinivas Rao Ganipisetti, Hyunjoo Cha-Molstad, Joonsung Hwang, Kyung Ho Lee, Sung-Kyun Ko, Jae-Hyuk Jang, In-Ja Ryoo, Yong Tae Kwon, Kyung Sang Lee, Hiroyuki Osada, Kyeong Lee, Bo Yeon Kim, Jong Seog Ahn
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-14 (2019)
Cancer: How a plant metabolite analog suppresses tumor growth A synthetic analog of a chemical found in fruit suppresses tumor growth by targeting an RNA-binding protein (hnRNPA2B1) and preventing the production of a pro-cancer regulatory factor. Nak
Externí odkaz:
https://doaj.org/article/590b138997084a14a74110e5433070ff
Autor:
Chang Hoon Ji, Hee Yeon Kim, Min Ju Lee, Ah Jung Heo, Daniel Youngjae Park, Sungsu Lim, Seulgi Shin, Srinivasrao Ganipisetti, Woo Seung Yang, Chang An Jung, Kun Young Kim, Eun Hye Jeong, Sun Ho Park, Su Bin Kim, Su Jin Lee, Jeong Eun Na, Ji In Kang, Hyung Min Chi, Hyun Tae Kim, Yun Kyung Kim, Bo Yeon Kim, Yong Tae Kwon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/21b691d9004c4b9f97ea92429f17feb7