Zobrazeno 1 - 10
of 673
pro vyhledávání: '"Yong Ryu"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2116-2121 (2024)
De novo drug design aims to rationally discover novel and potent compounds while reducing experimental costs during the drug development stage. Despite the numerous generative models that have been developed, few successful cases of drug design utili
Externí odkaz:
https://doaj.org/article/e0bb1cfa200c4e0386225c6c609b19fe
Autor:
Suhyun Hwangbo, Gahee Kim, Yongwook Choi, Yong Kwang Park, Songmee Bae, Jae Yong Ryu, Wonhee Hur
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Chronic hepatitis B virus (HBV) infection affects around 250 million people worldwide, causing approximately 887,000 deaths annually, primarily owing to cirrhosis and hepatocellular carcinoma (HCC). The current approved treatments
Externí odkaz:
https://doaj.org/article/53455c747cfc461dbb5003e01f5a7052
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 287, Iss , Pp 117307- (2024)
Ivermectin (IVM) is a widely used anthelmintic in human and veterinary medicine. However, the increasing use of IVM raises concerns about its potential harm against non-targeted organisms. This study demonstrates a novel mechanism where IVM triggers
Externí odkaz:
https://doaj.org/article/5bb2faa92d3e4879bbf59994c663b307
Autor:
Seok-Man Kim, Yong-Hee Kim, Gil Un Han, Seul Gi Kim, Bang-Jin Kim, Sung-Hwan Moon, Seung Hee Shin, Buom-Yong Ryu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Phthalate esters (PAEs) are primary plasticizers and endocrine-disrupting chemicals (EDCs) that are extensively used in numerous everyday consumer products. Although the adverse effects of single PAEs have been studied, our understanding of the effec
Externí odkaz:
https://doaj.org/article/066d4312ccc547c0a87e40d97a1276ed
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116544- (2024)
Benzyl butyl phthalate (BBP) is a widely used plasticizer that poses various potential health hazards. Although BBP has been extensively studied, the direct mechanism underlying its toxicity in male germ cells remains unclear. Therefore, we investiga
Externí odkaz:
https://doaj.org/article/1e5b5e5517d74a7997c989daf19fc22f
Autor:
Seungjin Lee, Jinseop Ahn, Seok-Man Kim, Daehan Kim, Jiun Yeom, Jeongmok Kim, Joong Yull Park, Buom-Yong Ryu
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-13 (2023)
Abstract Microfluidic devices have emerged as powerful tools for cell-based experiments, offering a controlled microenvironment that mimic the conditions within the body. Numerous cell experiment studies have successfully utilized microfluidic channe
Externí odkaz:
https://doaj.org/article/542d5e8eaeb043f296cbe2e3b01e9628
Autor:
Jae Sung Cho, Dongsoo Yang, Cindy Pricilia Surya Prabowo, Mohammad Rifqi Ghiffary, Taehee Han, Kyeong Rok Choi, Cheon Woo Moon, Hengrui Zhou, Jae Yong Ryu, Hyun Uk Kim, Sang Yup Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Synthetic sRNAs allow knockdown of target genes at translational level, but have been restricted to a limited number of bacteria. Here, we report the development of a broad-host-range synthetic sRNA (BHR-sRNA) platform employing the RoxS sca
Externí odkaz:
https://doaj.org/article/58c38c14a34843a0ad24871a58b655c2
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Acute oral toxicity of drug candidates can lead to drug development failure; thus, predicting the acute oral toxicity of small compounds is important for successful drug development. However, evaluation of the acute oral toxicity
Externí odkaz:
https://doaj.org/article/d6b8684c9bcc40b2b0d82f4b6c54077e
Autor:
Sang-Eun Jung1,2, Buom-Yong Ryu1 byryu@cau.ac.kr
Publikováno v:
Clinical & Experimental Reproductive Medicine. Dec2023, Vol. 50 Issue 4, p213-222. 10p.
Publikováno v:
Animal, Vol 17, Iss 4, Pp 100750- (2023)
The regulation of adipose deposition in broiler chickens is an important factor for production efficiency to poultry producers and health concerns to customers. Although vitamin A and its metabolite [all-trans retinoic acid (atRA)] have been used for
Externí odkaz:
https://doaj.org/article/29dc4e74f97a4b6085983d4b81f0d23d