Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-13 (2020)
Abstract Background Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggr
Externí odkaz:
https://doaj.org/article/3cea977c93ed4b929f91cf219f252bbf
Publikováno v:
Cancer Medicine, Vol 9, Iss 5, Pp 1753-1767 (2020)
Abstract Molecular‐targeted therapies have demonstrated disappointing results against most advanced solid cancers. This may largey be attributed to irrational drug use against unselected cancers. We investigated the efficacy of dual MEK‐PI3K drug
Externí odkaz:
https://doaj.org/article/12a75ad4899c4fccac51f4dc6ad15f41
Autor:
Weilin Liu, Hongqi Chen, Zhi Zhu, Zuqiang Liu, Congrong Ma, Yong J. Lee, David L. Bartlett, Zong-Sheng Guo
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1425 (2022)
Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides. In this study, we explore the combination of a ferroptosis activator with an oncolytic vaccinia virus in tumor models. Erastin
Externí odkaz:
https://doaj.org/article/845fcbfbe9d346f2adef10925b7e5237
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 1, Pp 102-111 (2011)
During the immune response, neutrophils display localized mechanical events by interacting with their environment through the micro-vascular transit, trans-endothelial, and trans-epithelial migration. Nano-mechanical studies of human neutrophils on l
Externí odkaz:
https://doaj.org/article/4c14f18edfd04e0dabbe2aca3a9323c2
Autor:
Jin Hong Kim, Abdo J. Najy, Jian Li, Xu Luo, Hyeong‐Reh C. Kim, Mohammad Haroon Asif Choudry, Yong J. Lee
Publikováno v:
Journal of Cellular Physiology. 237:4180-4196
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor-mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3-interacting domain death agonist) plays an important role in TRAIL-induced apoptosis. Ferr
Autor:
Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Per Basse, Lisa M. Bailey, William T. Kwon, Se-Hoon Hong, Xinxin Song
Supplementary Figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f626a92fc7f8c3078f386ac295d97e
https://doi.org/10.1158/1535-7163.22507654.v1
https://doi.org/10.1158/1535-7163.22507654.v1
Autor:
Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Per Basse, Lisa M. Bailey, William T. Kwon, Se-Hoon Hong, Xinxin Song
Apoptotic activity of secretory TRAIL-armed NK cells in a contacting culture system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44df87e91e1fb52ea20e4e7601cb806e
https://doi.org/10.1158/1535-7163.22507660.v1
https://doi.org/10.1158/1535-7163.22507660.v1
Autor:
Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Per Basse, Lisa M. Bailey, William T. Kwon, Se-Hoon Hong, Xinxin Song
Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major dra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e538265efd7bb1be3b93988362c98246
https://doi.org/10.1158/1535-7163.c.6538753.v1
https://doi.org/10.1158/1535-7163.c.6538753.v1
Autor:
Yong Seok Park, Kalishwaralal Kalimuthu, Yong J. Lee, Ja Lok Ku, Jin Hong Kim, Xu Luo, Lin Zhang, M. Haroon A. Choudry
Publikováno v:
Journal of Cellular Physiology. 236:6666-6677
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions. We previously reported that glu
Autor:
Kalishwaralal Kalimuthu, Chenicheri K. Keerthana, Manikandan Mohan, Jaison Arivalagan, Johnson Retnaraj Samuel Selvan Christyraj, Michael A. Firer, Mohammad Haroon Asif Choudry, Ruby John Anto, Yong J. Lee
Publikováno v:
J Cell Biochem
Selenium is incorporated into the body via the selenocysteine biosynthesis pathway, which is critical in the synthesis of selenoproteins such as glutathione peroxidases and thioredoxin reductases. Selenoproteins, which play a key role in several biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf9fd8fbcf1fd7c7a0d17649480dfd3
https://europepmc.org/articles/PMC8940641/
https://europepmc.org/articles/PMC8940641/