Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Yong‐Xian Cheng"'
Autor:
Tian-Shu Kang, Yong-Ming Yan, Yuan Tian, Jun Zhang, Minghui Zhang, Yuxin Shu, Jinbo Huang, Jing He, Cheng-Tian Tao, Qian Zhu, Jinke Gu, Xiaopeng Lu, Yong-Xian Cheng, Wei-Guo Zhu
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110014- (2024)
Summary: The NAD+-dependent deacetylase SIRT7 is a pivotal regulator of DNA damage response (DDR) and a promising drug target for developing cancer therapeutics. However, limited progress has been made in SIRT7 modulator discovery. Here, we applied p
Externí odkaz:
https://doaj.org/article/713a4c4ce50a4b0a81c7306164ca42ef
Publikováno v:
Molecules, Vol 29, Iss 15, p 3491 (2024)
Three pairs of enantiomers and one achiral molecule that are new ethylated derivatives of sulfur and nitrogen-containing compounds named mantidisamides E–H (1–4), along with twenty known ones (5–24), were derived from the ethanol extract of Ten
Externí odkaz:
https://doaj.org/article/8cfda9b6166d454cbaf0d4c87367182b
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 789-799 (2023)
Six new compounds, including a tetralone 1, two xanthones 2 and 3, a flavan derivative 4, and two nor-diterpenoids 7 and 8, accompanied by two known flavan derivatives 5 and 6 and a known olefine acid (9) were isolated from whole bodies of Kronopolit
Externí odkaz:
https://doaj.org/article/12c370a61c3543348e5ae8e883f516ed
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 998-1007 (2023)
Five new eudesmane-type sesquiterpenoids (aquisinenoids F–J (1–5)) and five known compounds (6–10) were isolated from the agarwood of Aquilaria sinensis. Their structures, including absolute configurations, were identified by comprehensive spec
Externí odkaz:
https://doaj.org/article/db83f11ed7b2490ea246628d20337387
Publikováno v:
Molecules, Vol 29, Iss 5, p 1149 (2024)
Ganoderma lucidum, known as the “herb of spiritual potency”, is used for the treatment and prevention of various diseases, but the responsible constituents for its therapeutic effects are largely unknown. For the purpose of obtaining insight into
Externí odkaz:
https://doaj.org/article/6af9dce9be5a4debacfd6bdc8e475f97
Autor:
Yong-Ming Yan, Xin Shen, Yan-Peng Li, Yong-Kai Cao, Jiao-Jiao Zhang, Yan Wang, Yong-Xian Cheng
Publikováno v:
Medicinal Plant Biology, Vol 2, Iss 1, Pp 1-5 (2023)
The 2019 novel coronavirus (2019-nCoV) causes novel coronavirus pneumonia (NCP). Given that approved drug repurposing becomes a common strategy to quickly find antiviral treatments, a collection of FDA-approved drugs can be powerful resources for new
Externí odkaz:
https://doaj.org/article/2f2813a14886410899485b639825e93c
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1370-1371 (2023)
Externí odkaz:
https://doaj.org/article/ae9cbea13204499e83b3ba74e31d99ee
Autor:
Xiaolong Tang, Lizhi Cheng, Guo Li, Yong-Ming Yan, Fengting Su, Dan-Ling Huang, Shuping Zhang, Zuojun Liu, Minxian Qian, Ji Li, Yong-Xian Cheng, Baohua Liu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Tang et al. propose the use of a small molecule compound D6 to treat EGFRTKI resistant tumors. The authors demonstrate potent and selective inhibition of NSCLC with T790M-mediated EGFR-TKI resistance through inhibiting HSP90-mediated protein–protei
Externí odkaz:
https://doaj.org/article/560053fe438d4044929a4cd263e14187
Publikováno v:
Molecules, Vol 28, Iss 6, p 2822 (2023)
Five new monoterpenoids including three 1-hydroxymethyl-2-methyl cantharimide-type derivatives (1, 2, and 5) and two 1,2-dimethyl cantharimide-type derivatives (3 and 4), together with three known compounds (6–8) were isolated from the insect Mylab
Externí odkaz:
https://doaj.org/article/a5d968b62d08440b8636827ab5bfa3cd
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
(±)-Dimercochlearlactones A−J (1–10), ten pairs of novel meroterpenoid dimers and one known spirocochlealactone A (11), were isolated from Ganoderma mushrooms. The structural elucidation of new compounds, including their absolute configurations,
Externí odkaz:
https://doaj.org/article/9f160da063e842e585fe116db4037ac8