Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Yong‐Wei Sun"'
Autor:
Yu-Heng Zhu, Qin-Yuan Jia, Hong-Fei Yao, Zong-Hao Duan, Xue-Shi-Yu Ma, Jia-Hao Zheng, Yi-Fan Yin, Wei Liu, Jun-Feng Zhang, Rong Hua, Ding Ma, Yong-Wei Sun, Jian-Yu Yang, De-Jun Liu, Yan-Miao Huo
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background This study investigated the molecular mechanism of long intergenic non-protein coding RNA 1605 (LINC01605) in the process of tumor growth and liver metastasis of pancreatic ductal adenocarcinoma (PDAC). Methods LINC01605 was filte
Externí odkaz:
https://doaj.org/article/1bacd5c3238b402e9c0a00fb055ea2ff
Autor:
Jia-Hao Zheng, Yu-Heng Zhu, Jian Yang, Pei-Xuan Ji, Rui-Kang Zhao, Zong-Hao Duan, Hong-Fei Yao, Qin-Yuan Jia, Yi-Fan Yin, Li-Peng Hu, Qing Li, Shu-Heng Jiang, Yan-Miao Huo, Wei Liu, Yong-Wei Sun, De-Jun Liu
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114633- (2024)
Summary: Pancreatic ductal adenocarcinoma (PDAC) features substantial matrix stiffening and reprogrammed glucose metabolism, particularly the Warburg effect. However, the complex interplay between these traits and their impact on tumor advancement re
Externí odkaz:
https://doaj.org/article/3e191bdb041148d8ad4a43c8690cab09
Autor:
Jun-Zhe Zhang, Chuan-Xin Yang, Si Gao, Jun-Feng Bu, Qin-Qin Li, Hao-Lu Wang, Kai-Ni Yang, Shan-Shi Tong, Li-Jun Qian, Jin Zhang, Rong Hua, Yong-Wei Sun, Jia-Yan Yan, Wei Chen
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background As digital medicine has exerted profound influences upon diagnosis and treatment of hepatobiliary diseases, our study aims to investigate the accuracy of three-dimensional visualization and evaluation (3DVE) system in assessing th
Externí odkaz:
https://doaj.org/article/a56150f979164144aa160447470efa99
Autor:
Qing Li, Xiao-Xin Zhang, Li-Peng Hu, Bo Ni, Dong-Xue Li, Xu Wang, Shu-Heng Jiang, Hui Li, Min-Wei Yang, Yong-Sheng Jiang, Chun-Jie Xu, Xue-Li Zhang, Yan-Li Zhang, Pei-Qi Huang, Qin Yang, Yang Zhou, Jian-ren Gu, Gary Gui-Shan Xiao, Yong-wei Sun, Jun Li, Zhi-Gang Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Pancreatic ductal adenocarcinoma (PDAC) cells can utilise the tumour microenvironment to metastasise to the liver. Here the authors show that hepatoctyes overexpress SLIT2 to enable premetastatic niche formation for ROBO1-positive PDAC cells to suppo
Externí odkaz:
https://doaj.org/article/c0db6eed419d4fa68ab125432f399435
Autor:
Jian‐Yu Yang, Yan‐Miao Huo, Min‐Wei Yang, Yang Shen, De‐Jun Liu, Xue‐Liang Fu, Ling‐Ye Tao, Rui‐Zhe He, Jun‐Feng Zhang, Rong Hua, Shu‐Heng Jiang, Yong‐Wei Sun, Wei Liu
Publikováno v:
Molecular Oncology, Vol 15, Iss 11, Pp 3076-3090 (2021)
Hot spot gene mutations in splicing factor 3b subunit 1 (SF3B1) are observed in many types of cancer and create abundant aberrant mRNA splicing, which is profoundly implicated in tumorigenesis. Here, we identified that the SF3B1 K700E (SF3B1K700E) mu
Externí odkaz:
https://doaj.org/article/a9c8f091e2da47fb82b13e91b61dc03a
Autor:
Shu-Heng Jiang, Dejun Liu, Li-Peng Hu, Shan Zhang, Yanqiu Yu, Yong-Wei Sun, Jianguang Ji, Zhi-Gang Zhang
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104050- (2022)
Summary: Background: Cancer elicits a complex adaptive response in an organism. Limited information is available for the body-wide effects induced by cancer. Here, we evaluated multiorgan changes in mouse models of pancreatic ductal adenocarcinoma (P
Externí odkaz:
https://doaj.org/article/78a28158243e4b64bca89e839dd3acf5
Autor:
Xu Wang, Li-Peng Hu, Wei-Ting Qin, Qin Yang, De-Yu Chen, Qing Li, Kai-Xia Zhou, Pei-Qi Huang, Chun-Jie Xu, Jun Li, Lin-Li Yao, Ya-Hui Wang, Guang-Ang Tian, Jian-Yu Yang, Min-Wei Yang, De-Jun Liu, Yong-Wei Sun, Shu-Heng Jiang, Xue-Li Zhang, Zhi-Gang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive metastatic disease characterized by an immunosuppressive microenvironment. Here the authors show that a subset of P2RX1-negative neutrophils with immunosuppressive properties accumulate i
Externí odkaz:
https://doaj.org/article/e5c9f48dd02248afa64c33593ecd5868
Autor:
Jia-Hao Zheng, Hong-Fei Yao, Zong-Hao Duan, Pei-Xuan Ji, Jian Yang, Yu-Heng Zhu, Qin-Yuan Jia, Jian-Yu Yang, De-Jun Liu, Yong-Wei Sun, Peng-Cheng Chen, Pei-Dong Shi, Li Chen
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1336 (2022)
Pancreatic adenocarcinoma (PAAD), one of the most malignant tumors, not only has abundant mesenchymal components, but is also characterized by an extremely high metastatic risk. The purpose of this study was to construct a model of stroma- and metast
Externí odkaz:
https://doaj.org/article/980608430c6143848ce14c867014d020
Autor:
Rui-Zhe, He, Jia-Hao, Zheng, Hong-Fei, Yao, Da-Peng, Xu, Min-Wei, Yang, De-Jun, Liu, Yong-Wei, Sun, Yan-Miao, Huo
Publikováno v:
Hepatobiliary & Pancreatic Diseases International. 22:169-178
ADAMTS (a disintegrin and metalloproteinase with thrombospondin-like motifs) family, a group of extracellular multifunctional enzymes, has been proven to play a pivotal role in the tumor. In pancreatic cancer, the role and mechanism of this family re
Autor:
Yu-Heng, Zhu, Jia-Hao, Zheng, Qin-Yuan, Jia, Zong-Hao, Duan, Hong-Fei, Yao, Jian, Yang, Yong-Wei, Sun, Shu-Heng, Jiang, De-Jun, Liu, Yan-Miao, Huo
Publikováno v:
Cellular Oncology. 46:17-48
Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, is characterized by poor treatment response and low survival time. The current clinical treatment for advanced PDAC is still not effective. In recent years, the resea